Identification of MMP1 as a novel risk factor for intracranial aneurysms in ADPKD using iPSC models
暂无分享,去创建一个
K. Nakao | T. Ichisaka | S. Yamanaka | D. Taura | M. Sone | Kazutoshi Takahashi | Y. Mori | Y. Ubara | T. Nakahata | K. Osafune | A. Koizumi | Yasuhiro Yamada | Masahiro Nakamura | A. Watanabe | I. Asaka | T. Numata | A. Fukatsu | Yasunori Sato | T. Araoka | T. Yasuno | E. Muso | Hatasu Kobayashi | Taro Toyoda | Naoya Kondo | Tomonaga Ameku | Fumihiko Shiota | Naoki Amano | Shin-ichi Mae | S. Inoue | S. Matsui | N. Matsuura | Sayaka Arai | Takuya Yamamoto | Fumiyo Kitaoka | Takuya Yamamoto
[1] M. Delgado-Rodríguez,et al. Systematic review and meta-analysis. , 2017, Medicina intensiva.
[2] T. Yokoo,et al. A comprehensive search for mutations in the PKD1 and PKD2 in Japanese subjects with autosomal dominant polycystic kidney disease , 2015, Clinical genetics.
[3] Tetsushi Sakuma,et al. Precise Correction of the Dystrophin Gene in Duchenne Muscular Dystrophy Patient Induced Pluripotent Stem Cells by TALEN and CRISPR-Cas9 , 2014, Stem cell reports.
[4] R. Serra,et al. The role of matrix metalloproteinases and neutrophil gelatinase-associated lipocalin in central and peripheral arterial aneurysms. , 2015, Surgery.
[5] P. Stather,et al. Meta‐analysis and meta‐regression analysis of biomarkers for abdominal aortic aneurysm , 2014, The British journal of surgery.
[6] Ajay V. Srivastava,et al. Autosomal dominant polycystic kidney disease. , 2014, American family physician.
[7] T. Ichisaka,et al. Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells , 2013, Proceedings of the National Academy of Sciences.
[8] C. Férec,et al. Type of PKD1 mutation influences renal outcome in ADPKD. , 2013, Journal of the American Society of Nephrology : JASN.
[9] P. Harris,et al. The genetics of vascular complications in autosomal dominant polycystic kidney disease (ADPKD). , 2013, Current hypertension reviews.
[10] H. Rennert,et al. A novel long-range PCR sequencing method for genetic analysis of the entire PKD1 gene. , 2012, The Journal of molecular diagnostics : JMD.
[11] Lin Zou,et al. Identification of novel mutations in Chinese Hans with autosomal dominant polycystic kidney disease , 2011, BMC Medical Genetics.
[12] M. Sone,et al. Simple and Highly Efficient Method for Production of Endothelial Cells from Human Embryonic Stem Cells , 2011, Cell transplantation.
[13] A. Algra,et al. Prevalence of unruptured intracranial aneurysms, with emphasis on sex, age, comorbidity, country, and time period: a systematic review and meta-analysis , 2011, The Lancet Neurology.
[14] Robert D. Brown,et al. Extended follow-up of unruptured intracranial aneurysms detected by presymptomatic screening in patients with autosomal dominant polycystic kidney disease. , 2011, Clinical journal of the American Society of Nephrology : CJASN.
[15] Xibao Liu,et al. Local Ca2+ Entry Via Orai1 Regulates Plasma Membrane Recruitment of TRPC1 and Controls Cytosolic Ca2+ Signals Required for Specific Cell Functions , 2011, PLoS biology.
[16] C. Mei,et al. Screening for Intracranial Aneurysm in 355 Patients With Autosomal-Dominant Polycystic Kidney Disease , 2011, Stroke.
[17] K. Nakao,et al. Sirt1 plays an important role in mediating greater functionality of human ES/iPS-derived vascular endothelial cells. , 2010, Atherosclerosis.
[18] I. Drummond,et al. The ADPKD genes pkd1a/b and pkd2 regulate extracellular matrix formation , 2010, Disease Models & Mechanisms.
[19] M. DeRuiter,et al. Pkd1-inactivation in vascular smooth muscle cells and adaptation to hypertension , 2010, Laboratory Investigation.
[20] S. Suhr,et al. Telomere Dynamics in Human Cells Reprogrammed to Pluripotency , 2009, PloS one.
[21] F. Sachs,et al. Polycystin-1 and -2 Dosage Regulates Pressure Sensing , 2009, Cell.
[22] S. Nauli,et al. Ciliary Polycystin-2 Is a Mechanosensitive Calcium Channel Involved in Nitric Oxide Signaling Cascades , 2009, Circulation research.
[23] J. Balligand,et al. PKD1 haploinsufficiency is associated with altered vascular reactivity and abnormal calcium signaling in the mouse aorta , 2009, Pflügers Archiv - European Journal of Physiology.
[24] Jing Zhou,et al. Endothelial Cilia Are Fluid Shear Sensors That Regulate Calcium Signaling and Nitric Oxide Production Through Polycystin-1 , 2008, Circulation.
[25] Takashi Aoi,et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts , 2008, Nature Biotechnology.
[26] T. Ichisaka,et al. Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors , 2007, Cell.
[27] T. Graf. Faculty Opinions recommendation of Induction of pluripotent stem cells from adult human fibroblasts by defined factors. , 2007 .
[28] S. Nishikawa,et al. Pathway for Differentiation of Human Embryonic Stem Cells to Vascular Cell Components and Their Potential for Vascular Regeneration , 2007, Arteriosclerosis, thrombosis, and vascular biology.
[29] M. DeRuiter,et al. Pathogenic Sequence for Dissecting Aneurysm Formation in a Hypomorphic Polycystic Kidney Disease 1 Mouse Model , 2007, Arteriosclerosis, thrombosis, and vascular biology.
[30] K. Nozaki,et al. Role of TIMP-1 and TIMP-2 in the Progression of Cerebral Aneurysms , 2007, Stroke.
[31] S. Nielsen,et al. PKD1 haploinsufficiency causes a syndrome of inappropriate antidiuresis in mice. , 2007, Journal of the American Society of Nephrology : JASN.
[32] Fredrik Lanner,et al. Functional Arterial and Venous Fate Is Determined by Graded VEGF Signaling and Notch Status During Embryonic Stem Cell Differentiation , 2007, Arteriosclerosis, thrombosis, and vascular biology.
[33] Angela Wandinger-Ness,et al. Human ADPKD primary cyst epithelial cells with a novel, single codon deletion in the PKD1 gene exhibit defective ciliary polycystin localization and loss of flow-induced Ca2+ signaling. , 2007, American journal of physiology. Renal physiology.
[34] M. Riera,et al. Transcriptome analysis of a rat PKD model: Importance of genes involved in extracellular matrix metabolism. , 2006, Kidney international.
[35] D. Wallace,et al. Calcium restores a normal proliferation phenotype in human polycystic kidney disease epithelial cells. , 2005, Journal of the American Society of Nephrology : JASN.
[36] S. Somlo,et al. [Ca2+]i Reduction Increases Cellular Proliferation and Apoptosis in Vascular Smooth Muscle Cells: Relevance to the ADPKD Phenotype , 2005, Circulation research.
[37] Martijn H Breuning,et al. Lowering of Pkd1 expression is sufficient to cause polycystic kidney disease. , 2004, Human molecular genetics.
[38] M. DeRuiter,et al. Lowering of Pkd 1 expression is sufficient to cause polycystic kidney disease , 2004 .
[39] S. Somlo,et al. Pkd2 haploinsufficiency alters intracellular calcium regulation in vascular smooth muscle cells. , 2003, Human molecular genetics.
[40] Jeffrey M Slezak,et al. Association of mutation position in polycystic kidney disease 1 (PKD1) gene and development of a vascular phenotype , 2003, The Lancet.
[41] Yuichiro Yamada,et al. Mutation analysis in PKD1 of Japanese autosomal dominant polycystic kidney disease patients , 2002, Human mutation.
[42] S. Somlo,et al. Polycystin-2 is an intracellular calcium release channel , 2002, Nature Cell Biology.
[43] V. Torres,et al. Management of cerebral aneurysms in autosomal dominant polycystic kidney disease. , 2002, Journal of the American Society of Nephrology : JASN.
[44] M. Berridge,et al. The organisation and functions of local Ca(2+) signals. , 2001, Journal of cell science.
[45] E. Brown,et al. Polycystin-2 is a novel cation channel implicated in defective intracellular Ca(2+) homeostasis in polycystic kidney disease. , 2001, Biochemical and biophysical research communications.
[46] N. Gretz,et al. A possible role for metalloproteinases in renal cyst development. , 2001, American journal of physiology. Renal physiology.
[47] X. Chen,et al. Vascular expression of polycystin-2. , 1997, Journal of the American Society of Nephrology : JASN.
[48] A. Bakkaloğlu,et al. Mutation analysis of the entire PKD1 gene: genetic and diagnostic implications. , 2001, American journal of human genetics.
[49] G. Germino,et al. Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents , 2000, Nature.
[50] Jun Yamashita,et al. Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors , 2000, Nature.
[51] K. Klinger,et al. Polycystin 1 is required for the structural integrity of blood vessels. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[52] I. Ebihara,et al. Elevation of Serum Levels of Metalloproteinase-1, Tissue Inhibitor of Metalloproteinase-1 and Type IV Collagen, and Plasma Levels of Metalloproteinase-9 in Polycystic Kidney Disease , 2000, American Journal of Nephrology.
[53] Lin Geng,et al. Cardiac defects and renal failure in mice with targeted mutations in Pkd2 , 2000, Nature Genetics.
[54] Ann M. Johnson,et al. Mutation detection of PKD1 identifies a novel mutation common to three families with aneurysms and/or very-early-onset disease. , 1999, American journal of human genetics.
[55] S. Somlo,et al. Identification and Characterization of Polycystin-2, the PKD2 Gene Product* , 1999, The Journal of Biological Chemistry.
[56] R. Sandford,et al. Identification of mutations in the repeated part of the autosomal dominant polycystic kidney disease type 1 gene, PKD1, by long-range PCR. , 1999, American journal of human genetics.
[57] J. Calvet,et al. Matrix metalloproteinase-2 in a murine model of infantile-type polycystic kidney disease. , 1999, Journal of the American Society of Nephrology : JASN.
[58] J. Thomson,et al. Embryonic stem cell lines derived from human blastocysts. , 1998, Science.
[59] D. Chyatte,et al. Vascular extracellular matrix remodeling in cerebral aneurysms. , 1998, Journal of neurosurgery.
[60] G. Germino,et al. An unusual pattern of mutation in the duplicated portion of PKD1 is revealed by use of a novel strategy for mutation detection. , 1997, Human molecular genetics.
[61] G. Germino,et al. PKD1 interacts with PKD2 through a probable coiled-coil domain , 1997, Nature Genetics.
[62] V. Torres,et al. Vascular expression of polycystin. , 1997, Journal of the American Society of Nephrology : JASN.
[63] L Kruglyak,et al. Parametric and nonparametric linkage analysis: a unified multipoint approach. , 1996, American journal of human genetics.
[64] Patricia A. Gabow,et al. PKD2, a Gene for Polycystic Kidney Disease That Encodes an Integral Membrane Protein , 1996, Science.
[65] F Matzkies,et al. Tubular gelatinase A (MMP-2) and its tissue inhibitors in polycystic kidney disease in the Han:SPRD rat. , 1996, Kidney international.
[66] R. Perrone,et al. Matrix metalloproteinase activity in human intrahepatic biliary epithelial cell lines from patients with autosomal dominant polycystic kidney disease. , 1996, Connective tissue research.
[67] J. Hughes,et al. The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains , 1995, Nature Genetics.
[68] P. Bork,et al. Polycystic kidney disease: The complete structure of the PKD1 gene and its protein , 1995, Cell.
[69] Polycystic kidney disease: the complete structure of the PKD1 gene and its protein. The International Polycystic Kidney Disease Consortium. , 1995, Cell.
[70] B. Sobel. Extrarenal manifestations of autosomal dominant polycystic kidney disease. , 1992, Seminars in Nephrology.
[71] W. D. Kaehny,et al. Extrarenal manifestations of autosomal dominant polycystic kidney disease. , 1991, Seminars in nephrology.
[72] Andrew P. McMahon,et al. The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain , 1990, Cell.