Statistical and cross-correlation structure of Jones-matrix images of polycrystalline films of biological fluids

The paper presents the results of Jones-matrix mapping of optically thin, non-depolarizing biological fluids with different polycrystalline structure – bile and cerebrospinal fluid (liquor). The Jones matrix model of manifestations of polarizing mechanisms of phase anisotropy of such layers is presented. The technique of experimental measurement of coordinate distributions of the modulus and phase values of Jones matrix elements is suggested. Within the statistical and cross-correlation approaches the modulus and phase maps of Jones matrix images of optically thin layers of polycrystalline films of plasma and cerebrospinal fluid are analyzed. A set of objective parameters (statistical and generalized correlation moments), which are the most sensitive to changes in the phase of anisotropy, associated with the features of polycrystalline structure of films of biological fluids of various organs are determined.

[1]  Angelo Pierangelo,et al.  Mueller matrix imaging of human colon tissue for cancer diagnostics: how Monte Carlo modeling can help in the interpretation of experimental data. , 2010, Optics express.

[2]  O V Angelsky,et al.  Measurement of small light absorption in microparticles by means of optically induced rotation. , 2015, Optics express.

[3]  A. G. Ushenko,et al.  Scattering of laser radiation by multifractal biological structures , 2000 .

[4]  V P Lukin,et al.  Optical correlation algorithm for reconstructing phase skeleton of complex optical fields for solving the phase problem. , 2014, Optics express.

[5]  Asima Pradhan,et al.  Mueller decomposition images for cervical tissue: potential for discriminating normal and dysplastic states. , 2009, Optics express.

[6]  David A. Boas,et al.  "Handbook of biomedical optics", edited by David A. Boas, Constantinos Pitris, and Nimmi Ramanujam , 2012, BioMedical Engineering OnLine.

[7]  Michael I. Mishchenko Tissue Optics: Light Scattering Methods and Instruments for Medical Diagnostics, 2nd ed, V. Tuchin. SPIE Press, Bellingham, WA (2007), Hardbound, ISBN 0-8194-6433-3, xl+841pp , 2009 .

[8]  Dinh Tuan Vo Biomedical photonics handbook , 2003 .

[9]  Steen G Hanson,et al.  Optical correlation diagnostics of rough surfaces with large surface inhomogeneities. , 2006, Optics express.

[10]  Nirmalya Ghosh,et al.  Tissue polarimetry: concepts, challenges, applications, and outlook. , 2011, Journal of biomedical optics.

[11]  Lihong V. Wang,et al.  Biomedical Optics: Principles and Imaging , 2007 .

[12]  Oleg V. Angelsky,et al.  New feasibilities for characterizing rough surfaces by optical correlation techniques , 2003, Saratov Fall Meeting.

[13]  A. G. Ushenko The vector structure of laser biospeckle fields and polarization diagnostics of collagen skin structures , 2000 .

[14]  O V Angelsky,et al.  Investigation of the correlation structure of biological tissue polarization images during the diagnostics of their oncological changes , 2005, Physics in medicine and biology.

[15]  Hui Ma,et al.  Mueller matrix polarimetry for differentiating characteristic features of cancerous tissues , 2014, Journal of biomedical optics.

[16]  Shaoqun Zeng,et al.  Characterization of backscattering Mueller matrix patterns of highly scattering media with triple scattering assumption. , 2007, Optics express.

[17]  G. Müller,et al.  Medical Optical Tomography: Functional Imaging and Monitoring , 1993 .

[18]  A. Thetford Introduction to Matrix Methods in Optics , 1976 .

[19]  Paul J. Wu,et al.  Stokes polarimetry imaging of rat tail tissue in a turbid medium: degree of linear polarization image maps using incident linearly polarized light. , 2006, Journal of biomedical optics.

[20]  V. O. Ushenko Spatial-frequency polarization phasometry of biological polycrystalline networks , 2013, Optical Memory and Neural Networks.

[21]  Gang Yao,et al.  Mueller matrix decomposition of diffuse reflectance imaging in skeletal muscle. , 2009, Applied optics.

[22]  A. V. Dubolazov,et al.  Wavelet-analysis of polarization maps of human blood plasma , 2012 .

[23]  Alexander G. Ushenko Polarization structure of laser scattering field , 1995 .

[24]  Angelo Pierangelo,et al.  Multispectral Mueller polarimetric imaging detecting residual cancer and cancer regression after neoadjuvant treatment for colorectal carcinomas , 2013, Journal of biomedical optics.