Single-cell RNA sequencing reveals the dynamics of hepatic non-parenchymal cells in autoprotection against acetaminophen-induced hepatotoxicity

[1]  R. Vernal,et al.  Neutrophil N1 and N2 Subsets and Their Possible Association with Periodontitis: A Scoping Review , 2022, International journal of molecular sciences.

[2]  A. Bell,et al.  Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b , 2022, Cell reports. Medicine.

[3]  Zuolin Wang,et al.  A novel lineage of osteoprogenitor cells with dual epithelial and mesenchymal properties govern maxillofacial bone homeostasis and regeneration after MSFL , 2022, Cell Research.

[4]  Aleksandra A. Kolodziejczyk,et al.  The spatiotemporal program of zonal liver regeneration following acute injury. , 2022, Cell stem cell.

[5]  P. Song,et al.  Notch-Regulated c-Kit–Positive Liver Sinusoidal Endothelial Cells Contribute to Liver Zonation and Regeneration , 2022, Cellular and molecular gastroenterology and hepatology.

[6]  Y. Tao,et al.  Pharmacotherapies for Drug-Induced Liver Injury: A Current Literature Review , 2022, Frontiers in Pharmacology.

[7]  E. Ballestar,et al.  Tolerogenic Dendritic Cells in Autoimmunity and Inflammatory Diseases. , 2020, Trends in immunology.

[8]  T. Horng,et al.  Lipid Metabolism in Regulation of Macrophage Functions. , 2020, Trends in cell biology.

[9]  Gaofeng Wang,et al.  Neutrophil extracellular traps impair regeneration , 2020, bioRxiv.

[10]  S. Möller,et al.  An Attempt to Polarize Human Neutrophils Toward N1 and N2 Phenotypes in vitro , 2020, Frontiers in Immunology.

[11]  W. Goessling,et al.  Functional compensation precedes recovery of tissue mass following acute liver injury , 2020, Nature Communications.

[12]  Jiandie D. Lin,et al.  Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis. , 2019, Molecular cell.

[13]  R. Andrade,et al.  Endoplasmic Reticulum Stress-induced Upregulation of STARD1 Promotes Acetaminophen-induced Acute Liver Failure. , 2019, Gastroenterology.

[14]  D. Sancho,et al.  Metabolic Control of Dendritic Cell Functions: Digesting Information , 2019, Front. Immunol..

[15]  H. Gröne,et al.  The Atypical Chemokine Receptor 2 Limits Progressive Fibrosis after Acute Ischemic Kidney Injury. , 2019, The American journal of pathology.

[16]  Michael J. T. Stubbington,et al.  Single-cell reconstruction of the early maternal–fetal interface in humans , 2018, Nature.

[17]  T. Iwanaga,et al.  Intestinal Lymphatic Endothelial Cells Produce R-Spondin3 , 2018, Scientific Reports.

[18]  Ana E. Paiva,et al.  Macrophage‐derived GPNMB accelerates skin healing , 2018, Experimental dermatology.

[19]  F. Bazer,et al.  C-C motif chemokine ligand 2 induces proliferation and prevents lipopolysaccharide-induced inflammatory responses in bovine mammary epithelial cells. , 2018, Journal of dairy science.

[20]  H. Bi,et al.  p53 attenuates acetaminophen-induced hepatotoxicity by regulating drug-metabolizing enzymes and transporter expression , 2018, Cell Death & Disease.

[21]  T. Yoshimura The chemokine MCP-1 (CCL2) in the host interaction with cancer: a foe or ally? , 2018, Cellular & Molecular Immunology.

[22]  Radika Soysa,et al.  Dendritic cells in hepatitis and liver transplantation , 2017, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

[23]  Michael J. T. Stubbington,et al.  Single-cell transcriptomics to explore the immune system in health and disease , 2017, Science.

[24]  T. Yoshimura The production of monocyte chemoattractant protein-1 (MCP-1)/CCL2 in tumor microenvironments. , 2017, Cytokine.

[25]  Hannah A. Pliner,et al.  Reversed graph embedding resolves complex single-cell trajectories , 2017, Nature Methods.

[26]  Cheng Huang,et al.  Macrophage Phenotype in Liver Injury and Repair , 2017, Scandinavian journal of immunology.

[27]  E. Morrisey,et al.  Neutrophils promote alveolar epithelial regeneration by enhancing type II pneumocyte proliferation in a model of acid-induced acute lung injury. , 2016, American journal of physiology. Lung cellular and molecular physiology.

[28]  G. Sutter,et al.  CCL2 expression is mediated by type I IFN receptor and recruits NK and T cells to the lung during MVA infection , 2016, Journal of leukocyte biology.

[29]  Courtney A Cates,et al.  Temporal neutrophil polarization following myocardial infarction. , 2016, Cardiovascular research.

[30]  Yujing Chi,et al.  Gut‐derived lymphocyte recruitment to liver and induce liver injury in non‐alcoholic fatty liver disease mouse model , 2016, Journal of gastroenterology and hepatology.

[31]  J. Connolly,et al.  Metabolism Is Central to Tolerogenic Dendritic Cell Function , 2016, Mediators of inflammation.

[32]  H. Augustin,et al.  Endothelial RSPO3 Controls Vascular Stability and Pruning through Non-canonical WNT/Ca(2+)/NFAT Signaling. , 2016, Developmental cell.

[33]  E. Pearce,et al.  Immunometabolism governs dendritic cell and macrophage function , 2016, The Journal of experimental medicine.

[34]  H. Okamoto,et al.  The Angiocrine Factor Rspondin3 Is a Key Determinant of Liver Zonation. , 2015, Cell reports.

[35]  Guozhong Tao,et al.  Augmented Wnt signaling as a therapeutic tool to prevent ischemia/reperfusion injury in liver: Preclinical studies in a mouse model , 2015, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

[36]  N. Kitteringham,et al.  Adaptation to acetaminophen exposure elicits major changes in expression and distribution of the hepatic proteome , 2015, Scientific Reports.

[37]  Xiang Gao,et al.  Natural Killer Cells-Produced IFN-γ Improves Bone Marrow-Derived Hepatocytes Regeneration in Murine Liver Failure Model , 2015, Scientific Reports.

[38]  Michael D. Schneider,et al.  Monocyte/Macrophage-derived IGF-1 Orchestrates Murine Skeletal Muscle Regeneration and Modulates Autocrine Polarization. , 2015, Molecular therapy : the journal of the American Society of Gene Therapy.

[39]  S. Tian,et al.  Macrophage polarization in kidney diseases. , 2015, Macrophage.

[40]  R. Sun,et al.  TIGIT safeguards liver regeneration through regulating natural killer cell‐hepatocyte crosstalk , 2014, Hepatology.

[41]  Ronald N Hines,et al.  Tolerance to acetaminophen hepatotoxicity in the mouse model of autoprotection is associated with induction of flavin-containing monooxygenase-3 (FMO3) in hepatocytes. , 2014, Toxicological sciences : an official journal of the Society of Toxicology.

[42]  Y. Cho,et al.  Characteristics of liver injury in drug-induced systemic hypersensitivity reactions. , 2013, Journal of the American Academy of Dermatology.

[43]  L. DeLeve,et al.  Liver sinusoidal endothelial cells and liver regeneration. , 2013, The Journal of clinical investigation.

[44]  G. Graham,et al.  Regulation of the immune and inflammatory responses by the 'atypical' chemokine receptor D6 , 2013, The Journal of pathology.

[45]  Christopher D. Conrady,et al.  IFN-α-driven CCL2 Production Recruits Inflammatory Monocytes to Infection Site in Mice , 2012, Mucosal Immunology.

[46]  Guangchuang Yu,et al.  clusterProfiler: an R package for comparing biological themes among gene clusters. , 2012, Omics : a journal of integrative biology.

[47]  A. Malhotra,et al.  Dendritic cell depletion exacerbates acetaminophen hepatotoxicity , 2011, Hepatology.

[48]  Jinghang Zhang,et al.  CCL2 recruits inflammatory monocytes to facilitate breast tumor metastasis , 2011, Nature.

[49]  N. Rooijen,et al.  NK cells suppress experimental cholestatic liver injury by an interleukin-6-mediated, Kupffer cell-dependent mechanism. , 2011, Journal of hepatology.

[50]  B. Cieply,et al.  Beta-catenin activation promotes liver regeneration after acetaminophen-induced injury. , 2009, The American journal of pathology.

[51]  M. L. Ruiz,et al.  Effect of repeated administration with subtoxic doses of acetaminophen to rats on enterohepatic recirculation of a subsequent toxic dose. , 2009, Biochemical Pharmacology.

[52]  H. Augustin,et al.  The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development , 2008, Development.

[53]  A. Ben-Baruch,et al.  The inflammatory chemokines CCL2 and CCL5 in breast cancer. , 2008, Cancer letters.

[54]  J. Manautou,et al.  Acquired resistance to acetaminophen hepatotoxicity is associated with induction of multidrug resistance-associated protein 4 (Mrp4) in proliferating hepatocytes. , 2008, Toxicological sciences : an official journal of the Society of Toxicology.

[55]  S. Nagata,et al.  Identification of Tim4 as a phosphatidylserine receptor , 2007, Nature.

[56]  A. Dolganiuc,et al.  Innate immune response and hepatic inflammation. , 2007, Seminars in liver disease.

[57]  W. Jeong,et al.  Activation of natural killer cells inhibits liver fibrosis: a novel strategy to treat liver fibrosis , 2007, Expert review of gastroenterology & hepatology.

[58]  S. Sozzani,et al.  Dendritic cell-endothelial cell cross-talk in angiogenesis. , 2007, Trends in immunology.

[59]  A. P. Holt,et al.  Attenuated liver fibrosis in the absence of B cells , 2006, Hepatology.

[60]  M. Miyazaki,et al.  Vascular endothelial growth factor and angiopoietins regulate sinusoidal regeneration and remodeling after partial hepatectomy in rats. , 2005, World journal of gastroenterology.

[61]  S. Thorgeirsson,et al.  Progenitor cells in liver regeneration: molecular responses controlling their activation and expansion , 2005, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[62]  R. Sun,et al.  Negative regulation of liver regeneration by innate immunity (natural killer cells/interferon-gamma). , 2004, Gastroenterology.

[63]  R. DeMatteo,et al.  Liver Dendritic Cells Are Less Immunogenic Than Spleen Dendritic Cells because of Differences in Subtype Composition1 , 2004, The Journal of Immunology.

[64]  H. Young,et al.  Expression of IFN-γ Upon Triggering of Activating Ly49D NK Receptors In Vitro and In Vivo: Costimulation with IL-12 or IL-18 Overrides Inhibitory Receptors 1 , 2003, The Journal of Immunology.

[65]  T. Sato,et al.  Sinusoidal endothelial cell proliferation and expression of angiopoietin/Tie family in regenerating rat liver. , 2001, Journal of hepatology.

[66]  N. Tygstrup,et al.  Autoprotection in acetaminophen intoxication in rats: the role of liver regeneration. , 2001, Pharmacology & toxicology.

[67]  S. Govindarajan,et al.  NK Cells Cause Liver Injury and Facilitate the Induction of T Cell-Mediated Immunity to a Viral Liver Infection1 , 2000, The Journal of Immunology.

[68]  J. Waltenberger,et al.  Regulation der Endothelfunktion und der Angiogenese durch den Vaskulären Endothelialen Wachstumsfaktor-A (VEGF-A) , 2000, Zeitschrift für Kardiologie.

[69]  H. Okamura,et al.  Regulation of interferon-γ production by IL-12 and IL-18 , 1998 .

[70]  H. Mehendale,et al.  Hepatocellular regeneration: key to thioacetamide autoprotection. , 1995, Pharmacology & toxicology.

[71]  Harihara M. Mehendale,et al.  Role of Hepatocellular Regeneration in CCl4 Autoprotection , 1991, Toxicologic pathology.

[72]  W. Anderson,et al.  Modification of ribosomal proteins during liver regeneration. , 1975, Biochemical and biophysical research communications.

[73]  T. E. Webb,et al.  Regulation of ribosome formation in regenerating rat liver. , 1972, European journal of biochemistry.

[74]  Ahmed Enayetallah,et al.  Analysis of changes in hepatic gene expression in a murine model of tolerance to acetaminophen hepatotoxicity (autoprotection). , 2014, Toxicology and applied pharmacology.

[75]  H. Mehendale,et al.  2-Butoxyethanol autoprotection is due to resiliance of newly formed erythrocytes to hemolysis , 2009, Archives of Toxicology.

[76]  D. Brenner,et al.  NK and NKT cells in liver injury and fibrosis. , 2009, Clinical immunology.

[77]  A. Larson Acetaminophen hepatotoxicity. , 2007, Clinics in liver disease.

[78]  William M. Lee,et al.  LIVER FAILURE AND LIVER DISEASE LIVER FAILURE Acetaminophen-Induced Acute Liver Failure: Results of a United States Multicenter, Prospective Study , 2005 .

[79]  H. Wild [Conflict-centered group discussion in the industrial outpatient clinic]. , 1973, Zeitschrift fur arztliche Fortbildung.