Age- and diet-dependent requirement of DJ-1 for glucose homeostasis in mice with implications for human type 2 diabetes.
暂无分享,去创建一个
M. Bugliani | P. Marchetti | L. Piemonti | D. Eberhard | E. Lammert | J. Eglinger | D. Jain | Ruchi Jain
[1] T. Foltynie,et al. Parkinson's disease, insulin resistance and novel agents of neuroprotection. , 2013, Brain : a journal of neurology.
[2] M. Cookson,et al. Mitochondrial quality control and dynamics in Parkinson's disease. , 2012 .
[3] D. Surmeier,et al. The role of calcium and mitochondrial oxidant stress in the loss of substantia nigra pars compacta dopaminergic neurons in Parkinson's disease , 2011, Neuroscience.
[4] X. Wang,et al. ROS acts as a double-edged sword in the pathogenesis of type 2 diabetes mellitus: is Nrf2 a potential target for the treatment? , 2011, Mini reviews in medicinal chemistry.
[5] R. Aebersold,et al. Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass. , 2011, Cell metabolism.
[6] T. Nazarenus,et al. A Plant DJ-1 Homolog Is Essential for Arabidopsis thaliana Chloroplast Development , 2011, PloS one.
[7] Y. Kitamura,et al. Neuroprotective effect of a new DJ-1-binding compound against neurodegeneration in Parkinson's disease and stroke model rats , 2011, Molecular Neurodegeneration.
[8] Yiming Li,et al. GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes , 2011, Proceedings of the National Academy of Sciences.
[9] H. Adami,et al. Epidemiology and etiology of Parkinson’s disease: a review of the evidence , 2011, European Journal of Epidemiology.
[10] Mary T. Brinkoetter,et al. A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis , 2011, Nature Medicine.
[11] Xuemei Huang,et al. Diabetes and Risk of Parkinson’s Disease , 2011, Diabetes Care.
[12] Wenbo Zhou,et al. Phenylbutyrate Up-regulates the DJ-1 Protein and Protects Neurons in Cell Culture and in Animal Models of Parkinson Disease* , 2011, The Journal of Biological Chemistry.
[13] G. Lewis,et al. Sodium Phenylbutyrate, a Drug With Known Capacity to Reduce Endoplasmic Reticulum Stress, Partially Alleviates Lipid-Induced Insulin Resistance and β-Cell Dysfunction in Humans , 2011, Diabetes.
[14] O. Riess,et al. Localization of sequence variations in PGC-1α influence their modifying effect in Huntington disease , 2011, Molecular Neurodegeneration.
[15] L. Groop,et al. Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA1c levels in human pancreatic islets , 2010, Diabetologia.
[16] Paul T. Schumacker,et al. Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1 , 2010, Nature.
[17] H. Heimberg,et al. Pancreatic beta-cells: from generation to regeneration. , 2010, Seminars in cell & developmental biology.
[18] T. Dick,et al. Fluorescent protein-based redox probes. , 2010, Antioxidants & redox signaling.
[19] K. Wanic,et al. The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells. , 2010, The Journal of clinical investigation.
[20] M. Linial,et al. Protection of Pancreatic β-Cells from Various Stress Conditions Is Mediated by DJ-1* , 2010, The Journal of Biological Chemistry.
[21] M. Palassini,et al. Derepression of Polycomb targets during pancreatic organogenesis allows insulin-producing beta-cells to adopt a neural gene activity program. , 2010, Genome research.
[22] X. Xu,et al. The Arabidopsis DJ-1a protein confers stress protection through cytosolic SOD activation , 2010, Journal of Cell Science.
[23] N. Bonini,et al. DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function , 2010, Proceedings of the National Academy of Sciences.
[24] J. Bereiter-Hahn,et al. Decreased expression of Drp1 and Fis1 mediates mitochondrial elongation in senescent cells and enhances resistance to oxidative stress through PINK1 , 2010, Journal of Cell Science.
[25] Aneeka M Hancock,et al. DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease. , 2010, Brain : a journal of neurology.
[26] P. Herrera,et al. Conversion of Adult Pancreatic α-cells to β-cells After Extreme β-cell Loss , 2010, Nature.
[27] K. Takahashi-Niki,et al. DJ-1 binds to mitochondrial complex I and maintains its activity. , 2009, Biochemical and biophysical research communications.
[28] L. F. Waanders,et al. Quantitative proteomic analysis of single pancreatic islets , 2009, Proceedings of the National Academy of Sciences.
[29] David N. Groff,et al. Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress , 2009, Proceedings of the National Academy of Sciences.
[30] Mihaela Zavolan,et al. miR-375 maintains normal pancreatic α- and β-cell mass , 2009, Proceedings of the National Academy of Sciences.
[31] P. Marchetti,et al. Selective Actions of Mitochondrial Fission/Fusion Genes on Metabolism-Secretion Coupling in Insulin-releasing Cells*♦ , 2008, Journal of Biological Chemistry.
[32] S. Lenzen. Oxidative stress: the vulnerable beta-cell. , 2008, Biochemical Society transactions.
[33] K. Maedler. Beta cells in type 2 diabetes – a crucial contribution to pathogenesis , 2008, Diabetes, obesity & metabolism.
[34] L. Groop,et al. Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion , 2008, Diabetologia.
[35] Min Wu,et al. Fission and selective fusion govern mitochondrial segregation and elimination by autophagy , 2008, The EMBO journal.
[36] T. Dawson,et al. DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase , 2007, Proceedings of the National Academy of Sciences.
[37] V. Tang. Faculty Opinions recommendation of EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets. , 2007 .
[38] W. Wurst,et al. EphA-Ephrin-A-Mediated β Cell Communication Regulates Insulin Secretion from Pancreatic Islets , 2007, Cell.
[39] T. Mak,et al. DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2 , 2006, Proceedings of the National Academy of Sciences.
[40] E. Yilmaz,et al. Chemical Chaperones Reduce ER Stress and Restore Glucose Homeostasis in a Mouse Model of Type 2 Diabetes , 2006, Science.
[41] R. Robertson,et al. Diabetes, glucose toxicity, and oxidative stress: A case of double jeopardy for the pancreatic islet beta cell. , 2006, Free radical biology & medicine.
[42] A. Wiederkehr,et al. Minireview: implication of mitochondria in insulin secretion and action. , 2006, Endocrinology.
[43] Min Zhang,et al. Total insulin and IGF-I resistance in pancreatic β cells causes overt diabetes , 2006, Nature Genetics.
[44] E. Ding,et al. Sex differences of endogenous sex hormones and risk of type 2 diabetes: a systematic review and meta-analysis. , 2006, JAMA.
[45] D. Melton,et al. The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation. , 2006, Developmental cell.
[46] F. Ashcroft. ATP-sensitive potassium channelopathies: focus on insulin secretion. , 2005, The Journal of clinical investigation.
[47] K. Petersen,et al. Mitochondrial dysfunction and type 2 diabetes , 2005, Current diabetes reports.
[48] P. Calabresi,et al. Nigrostriatal Dopaminergic Deficits and Hypokinesia Caused by Inactivation of the Familial Parkinsonism-Linked Gene DJ-1 , 2005, Neuron.
[49] P. Rorsman,et al. Insulin Secretion , 2004, The Journal of general physiology.
[50] R. Robertson. Chronic Oxidative Stress as a Central Mechanism for Glucose Toxicity in Pancreatic Islet Beta Cells in Diabetes* , 2004, Journal of Biological Chemistry.
[51] R. P. Maguire,et al. PET neuroimaging and mutations in the DJ-1 gene , 2004, Journal of Neural Transmission.
[52] Mark A. Wilson,et al. The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[53] Devin Oglesbee,et al. Investigating Mitochondrial Redox Potential with Redox-sensitive Green Fluorescent Protein Indicators* , 2004, Journal of Biological Chemistry.
[54] G. Nijpels,et al. Mitochondrial diabetes: molecular mechanisms and clinical presentation. , 2004, Diabetes.
[55] T. Dawson,et al. Molecular Pathways of Neurodegeneration in Parkinson's Disease , 2003, Science.
[56] T. Niki,et al. DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex. , 2003, Molecular cancer research : MCR.
[57] Patrizia Rizzu,et al. Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism , 2002, Science.
[58] C. Graff,et al. Impaired insulin secretion and β-cell loss in tissue-specific knockout mice with mitochondrial diabetes , 2000, Nature Genetics.
[59] Y. Matsuzawa,et al. Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity. , 1999, Diabetes.
[60] R. Robertson,et al. Prevention of glucose toxicity in HIT-T15 cells and Zucker diabetic fatty rats by antioxidants. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[61] S. Toyokuni,et al. Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes. , 1999, Diabetes.
[62] S. Lenzen,et al. Relation Between Antioxidant Enzyme Gene Expression and Antioxidative Defense Status of Insulin-Producing Cells , 1997, Diabetes.
[63] J. Miyazaki,et al. Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms. , 1990, Endocrinology.
[64] K. Takata,et al. Protection against dopaminergic neurodegeneration in Parkinson's disease-model animals by a modulator of the oxidized form of DJ-1, a wild-type of familial Parkinson's disease-linked PARK7. , 2011, Journal of pharmacological sciences.
[65] Per-Olof Berggren,et al. Sirt1: a metabolic master switch that modulates lifespan , 2006, Nature Medicine.
[66] Min Zhang,et al. Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes. , 2006, Nature genetics.
[67] C. Wollheim,et al. Mitochondrial function in normal and diabetic beta-cells. , 2001, Nature.
[68] S. Lenzen,et al. Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues. , 1996, Free radical biology & medicine.