Longevity extension in Drosophila through gut-brain communication

[1]  S. Prakash,et al.  A polyphenol-rich prebiotic in combination with a novel probiotic formulation alleviates markers of obesity and diabetes in Drosophila , 2018, Journal of Functional Foods.

[2]  S. Prakash,et al.  A novel polyphenolic prebiotic and probiotic formulation have synergistic effects on the gut microbiota influencing Drosophila melanogaster physiology , 2018, Artificial cells, nanomedicine, and biotechnology.

[3]  I. A. de Medeiros,et al.  Aging: Molecular Pathways and Implications on the Cardiovascular System , 2017, Oxidative medicine and cellular longevity.

[4]  T. Buford.  (Dis)Trust your gut: the gut microbiome in age-related inflammation, health, and disease , 2017, Microbiome.

[5]  P. Sivaramakrishnan,et al.  Microbial Genetic Composition Tunes Host Longevity , 2017, Cell.

[6]  T. Dinan,et al.  Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration , 2017, The Journal of physiology.

[7]  J-J Jeong,et al.  Anti-inflammaging effects of Lactobacillus brevis OW38 in aged mice. , 2016, Beneficial microbes.

[8]  Y. Li,et al.  Gut microbiota signatures of longevity , 2016, Current Biology.

[9]  M. A. Saad,et al.  Linking Gut Microbiota and Inflammation to Obesity and Insulin Resistance. , 2016, Physiology.

[10]  S. Rampelli,et al.  Gut Microbiota and Extreme Longevity , 2016, Current Biology.

[11]  V. Krut’ko,et al.  Early thymus involution – Manifestation of an aging program or a program of development? , 2015, Biochemistry (Moscow).

[12]  D. Ingram,et al.  Improving healthspan via changes in gut microbiota and fermentation , 2015, AGE.

[13]  M. Pellegrini,et al.  Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality. , 2015, Cell reports.

[14]  Partho Sen,et al.  Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome. , 2015, Cell metabolism.

[15]  S. Turroni,et al.  Impact of personalized diet and probiotic supplementation on inflammation, nutritional parameters and intestinal microbiota - The "RISTOMED project": Randomized controlled trial in healthy older people. , 2015, Clinical nutrition.

[16]  J. Tower.  Mitochondrial maintenance failure in aging and role of sexual dimorphism. , 2015, Archives of biochemistry and biophysics.

[17]  A. Yashin,et al.  GxE interactions between FOXO genotypes and drinking tea are significantly associated with prevention of cognitive decline in advanced age in China. , 2015, The journals of gerontology. Series A, Biological sciences and medical sciences.

[18]  B. Morris,et al.  FOXO3: A Major Gene for Human Longevity - A Mini-Review , 2015, Gerontology.

[19]  C. Huh,et al.  Comparative analysis of gut microbiota in elderly people of urbanized towns and longevity villages , 2015, BMC Microbiology.

[20]  P. D’Aquila,et al.  Mitochondria in health, aging and diseases: the epigenetic perspective , 2015, Biogerontology.

[21]  D. Govindaraju,et al.  Genetics, lifestyle and longevity: Lessons from centenarians , 2015, Applied & translational genomics.

[22]  C. Janani,et al.  PPAR gamma gene--a review. , 2015, Diabetes & metabolic syndrome.

[23]  T. Dinan,et al.  Microbiota regulation of the Mammalian gut-brain axis. , 2015, Advances in applied microbiology.

[24]  R. Kapila,et al.  Dietary supplementation of milk fermented with probiotic Lactobacillus fermentum enhances systemic immune response and antioxidant capacity in aging mice. , 2014, Nutrition research.

[25]  S. Tacconelli,et al.  Gut Microbiota, Host Gene Expression, and Aging , 2014, Journal of clinical gastroenterology.

[26]  A. Koliada,et al.  Effect of dietary restriction during development on the level of expression of longevity-associated genes in Drosophila melanogaster , 2014, Advances in Gerontology.

[27]  E. Levy,et al.  A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. population in the gut microbiota of mice , 2014, Gut.

[28]  Brian E. Vestal,et al.  Contribution of Intestinal Barrier Damage, Microbial Translocation and HIV-1 Infection Status to an Inflammaging Signature , 2014, PloS one.

[29]  M. Rämet,et al.  The Drosophila Imd Signaling Pathway , 2014, The Journal of Immunology.

[30]  Hideyuki Suzuki,et al.  Upregulation of colonic luminal polyamines produced by intestinal microbiota delays senescence in mice , 2014, Scientific Reports.

[31]  Y. Li,et al.  The phytochemical, EGCG, extends lifespan by reducing liver and kidney function damage and improving age‐associated inflammation and oxidative stress in healthy rats , 2013, Aging cell.

[32]  H. Jasper,et al.  Intestinal inflammation and stem cell homeostasis in aging Drosophila melanogaster , 2013, Front. Cell. Infect. Microbiol..

[33]  V. Anisimov,et al.  The key role of growth hormone-insulin-IGF-1 signaling in aging and cancer. , 2013, Critical reviews in oncology/hematology.

[34]  Seung Geun Yeo,et al.  Aging , 2013, Korean journal of audiology.

[35]  Y. Ulrich‐Lai,et al.  PPARγ and stress: Implications for aging , 2013, Experimental Gerontology.

[36]  E. Lyon,et al.  Probiotics, Prebiotics and Immunomodulation of Gut Mucosal Defences: Homeostasis and Immunopathology , 2013, Nutrients.

[37]  Ravikumar Hosamani.  Acute exposure of Drosophila melanogaster to paraquat causes oxidative stress and mitochondrial dysfunction. , 2013, Archives of insect biochemistry and physiology.

[38]  J. M. Suh,et al.  PPARγ signaling and metabolism: the good, the bad and the future , 2013, Nature Medicine.

[39]  F. Ren,et al.  Lactobacillus salivarius strain FDB89 induced longevity in Caenorhabditis elegans by dietary restriction , 2013, Journal of Microbiology.

[40]  O. Shirihai,et al.  Mitochondrial dynamics in the regulation of nutrient utilization and energy expenditure. , 2013, Cell metabolism.

[41]  W. Lowe,et al.  Short chain fatty acids and their receptors: new metabolic targets. , 2013, Translational research : the journal of laboratory and clinical medicine.

[42]  A. Bratić,et al.  The role of mitochondria in aging. , 2013, The Journal of clinical investigation.

[43]  P. Rabinovitch,et al.  mTOR is a key modulator of ageing and age-related disease , 2013, Nature.

[44]  B. Foligné,et al.  Anti-Inflammatory Lactobacillus rhamnosus CNCM I-3690 Strain Protects against Oxidative Stress and Increases Lifespan in Caenorhabditis elegans , 2012, PloS one.

[45]  D. Walker,et al.  Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila , 2012, Proceedings of the National Academy of Sciences.

[46]  D. Sinderen,et al.  Gut microbiota composition correlates with diet and health in the elderly , 2012, Nature.

[47]  I. Eleftherianos,et al.  Molecular Mechanisms of Aging and Immune System Regulation in Drosophila , 2012, International journal of molecular sciences.

[48]  V. Pertegato,et al.  Assessment of mitochondrial respiratory chain enzymatic activities on tissues and cultured cells , 2012, Nature Protocols.

[49]  Patrice D Cani,et al.  Involvement of gut microbiota in the development of low-grade inflammation and type 2 diabetes associated with obesity , 2012, Gut microbes.

[50]  Kira Glover-Cutter,et al.  TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO. , 2012, Cell metabolism.

[51]  R. de Cabo,et al.  The effect of resveratrol on lifespan depends on both gender and dietary nutrient composition in Drosophila melanogaster , 2011, AGE.

[52]  D. Walker,et al.  Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog. , 2011, Cell metabolism.

[53]  L. Santambrogio,et al.  Oxidative stress, inflamm-aging and immunosenescence. , 2011, Journal of proteomics.

[54]  Y. Benno,et al.  Longevity in Mice Is Promoted by Probiotic-Induced Suppression of Colonic Senescence Dependent on Upregulation of Gut Bacterial Polyamine Production , 2011, PloS one.

[55]  Sejong Oh,et al.  Evaluation of probiotic characteristics of newly isolated Lactobacillus spp.: immune modulation and longevity. , 2011, International journal of food microbiology.

[56]  T. Wenz.  Mitochondria and PGC-1α in Aging and Age-Associated Diseases , 2011, Journal of aging research.

[57]  David W. Walker,et al.  The Role of Mitochondria in Drosophila Aging , 2011, Experimental Gerontology.

[58]  K. Honda,et al.  Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species , 2011, Science.

[59]  N. Silverman,et al.  NF-κB/Rel proteins and the humoral immune responses of Drosophila melanogaster. , 2011, Current topics in microbiology and immunology.

[60]  Marcus J. Claesson,et al.  Composition, variability, and temporal stability of the intestinal microbiota of the elderly , 2010, Proceedings of the National Academy of Sciences.

[61]  P. Brigidi,et al.  Correction: Through Ageing, and Beyond: Gut Microbiota and Inflammatory Status in Seniors and Centenarians , 2010, PLoS ONE.

[62]  P. Brigidi,et al.  Through Ageing, and Beyond: Gut Microbiota and Inflammatory Status in Seniors and Centenarians , 2010, PloS one.

[63]  Linda Partridge,et al.  Extending Healthy Life Span—From Yeast to Humans , 2010, Science.

[64]  C. Kenyon.  The genetics of ageing , 2010, Nature.

[65]  T. Andrews,et al.  Molecular Evolution and Functional Characterization of Drosophila Insulin-Like Peptides , 2010, PLoS genetics.

[66]  M. Hoch,et al.  FOXO-dependent regulation of innate immune homeostasis , 2010, Nature.

[67]  L. Partridge,et al.  Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster , 2010, Cell metabolism.

[68]  J. Cullen,et al.  Measurement of superoxide dismutase, catalase and glutathione peroxidase in cultured cells and tissue , 2010, Nature Protocols.

[69]  A. Navarro,et al.  Brain mitochondrial dysfunction and oxidative damage in Parkinson’s disease , 2009, Journal of bioenergetics and biomembranes.

[70]  Marco Pahor,et al.  Rapamycin fed late in life extends lifespan in genetically heterogeneous mice , 2009, Nature.

[71]  Claudio R. Santos,et al.  SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth , 2008, Cell metabolism.

[72]  N. Gharavi,et al.  Inflammation and metabolic disorders , 2008, Current opinion in clinical nutrition and metabolic care.

[73]  Kyung-Jin Min,et al.  Drosophila lifespan control by dietary restriction independent of insulin-like signaling , 2008, Aging cell.

[74]  A. Sanz,et al.  The mitochondrial free radical theory of aging: a critical view. , 2008, Current aging science.

[75]  S. Gygi,et al.  An AMPK-FOXO Pathway Mediates Longevity Induced by a Novel Method of Dietary Restriction in C. elegans , 2007, Current Biology.

[76]  S. Murakami.  Stress resistance in long-lived mouse models , 2006, Experimental Gerontology.

[77]  Matt Kaeberlein,et al.  Extension of chronological life span in yeast by decreased TOR pathway signaling. , 2006, Genes & development.

[78]  Hanna Uvell.  Signaling and transcriptional regulation of antimicrobial peptide genes in Drosophila melanogaster. , 2006 .

[79]  D. Wallace.  A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine , 2005, Annual review of genetics.

[80]  P. Reddy,et al.  Time‐course of mitochondrial gene expressions in mice brains: implications for mitochondrial dysfunction, oxidative damage, and cytochrome c in aging , 2005, Journal of neurochemistry.

[81]  B. Pettmann,et al.  Foxo3a induces motoneuron death through the Fas pathway in cooperation with JNK , 2004, BMC Neuroscience.

[82]  E. Hafen,et al.  Long-Lived Drosophila with Overexpressed dFOXO in Adult Fat Body , 2004, Science.

[83]  C. Franceschi,et al.  Gender specific association of genetic variation in peroxisome proliferator-activated receptor (PPAR)γ-2 with longevity , 2004, Experimental Gerontology.

[84]  Simon Tavaré,et al.  Similar gene expression patterns characterize aging and oxidative stress in Drosophila melanogaster. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[85]  D. Praticò,et al.  Lipid peroxidation and oxidative imbalance: early functional events in Alzheimer's disease. , 2004, Journal of Alzheimer's disease : JAD.

[86]  B. Weinert,et al.  Invited review: Theories of aging. , 2003, Journal of applied physiology.

[87]  Matthias Blüher,et al.  Extended Longevity in Mice Lacking the Insulin Receptor in Adipose Tissue , 2003, Science.

[88]  B. Troen,et al.  The biology of aging. , 2003, The Mount Sinai journal of medicine, New York.

[89]  R. S. Sohal,et al.  Biochemical assay of superoxide dismutase activity in Drosophila. , 2002, Methods in enzymology.

[90]  H. Chung,et al.  Role of xanthine dehydrogenase and aging on the innate immune response of Drosophila , 2001, Journal of the American Aging Association.

[91]  I. Erdelmeier,et al.  Reactions of 1-methyl-2-phenylindole with malondialdehyde and 4-hydroxyalkenals. Analytical applications to a colorimetric assay of lipid peroxidation. , 1998, Chemical research in toxicology.