A Perspective on the Neurobiology of Language

This paper provides a perspective on current issues and challenges in the investigation of the neurobiology of language. It is proposed that the speech/language deficits of aphasic patients reflect impairments in the processing components involved in accessing language. More specifically, it is hypothesized that many of these deficits result from changes in the activation level of word candidates in the lexicon. Because word recognition and lexical access processes are crucially involved in virtually all aspects of language processing, such an impairment has repercussions throughout the components of the linguistic grammar. It is suggested that the intersection of such language behaviors with the identification of underlying neural systems will define future research directions. Methodological and technological issues are discussed as they impact on current and future research.

[1]  S. Petersen,et al.  Impaired non-motor learning and error detection associated with cerebellar damage. A single case study. , 1992, Brain : a journal of neurology.

[2]  Harold Goodglass,et al.  1 – Is Agrammatism a Unitary Phenomenon?* , 1985 .

[3]  M. Gazzaniga Handbook of Cognitive Neuroscience , 1984, Springer US.

[4]  S. E. Blumstein,et al.  Processing of lexical ambiguities in aphasia , 1987, Brain and Language.

[5]  R. S. Waldstein,et al.  The Role of Lexical Status on the Phonetic Categorization of Speech in Aphasia , 1994, Brain and Language.

[6]  Brian MacWhinney,et al.  Cross-linguistic research in aphasia: An overview , 1991, Brain and Language.

[7]  Hanna Damasio,et al.  3 – Neuroanatomical Correlates of the Aphasias , 1998 .

[8]  S. Blumstein,et al.  Phonological processing and lexical access in aphasia , 1988, Brain and Language.

[9]  Alfonso Caramazza,et al.  The logic of neuropsychological research and the problem of patient classification in aphasia , 1984, Brain and Language.

[10]  D. Swinney,et al.  The Effects of Focal Brain Damage on Sentence Processing: an examination of the neurological organization of a mental module , 1989, Journal of Cognitive Neuroscience.

[11]  Sheila E. Blumstein,et al.  Semantic processing in aphasia: Evidence from an auditory lexical decision task , 1982, Brain and Language.

[12]  S. Blumstein A Phonological Investigation of Aphasic Speech , 1973 .

[13]  N. Geschwind Disconnexion syndromes in animals and man. I. , 1965, Brain : a journal of neurology.

[14]  Edgar Zurif,et al.  Slowed lexical access in nonfluent aphasia: A case study , 1992, Brain and Language.

[15]  S. Blumstein,et al.  Lexical decision and aphasia: Evidence for semantic processing , 1981, Brain and Language.

[16]  D. Caplan,et al.  Syntactic determinants of sentence comprehension in aphasia , 1985, Cognition.

[17]  Myrna F. Schwartz,et al.  What the classical aphasia categories can't do for us, and why , 1984, Brain and Language.

[18]  Harold Goodglass,et al.  Phonological factors in auditory comprehension in aphasia , 1977, Neuropsychologia.

[19]  Sheila E Blumstein,et al.  Temporal dimensions of consonant and vowel production: An acoustic and CT scan analysis of aphasic speech , 1990, Brain and Language.

[20]  William F. Katz,et al.  An investigation of lexical ambiguity in Broca's aphasics using an auditory lexical priming technique , 1988, Neuropsychologia.

[21]  J. Schmahmann An emerging concept. The cerebellar contribution to higher function. , 1991, Archives of neurology.

[22]  S. Blumstein,et al.  The reliability of ear advantage in dichotic listening , 1975, Brain and Language.

[23]  Tim Shallice,et al.  Case study approach in neuropsychological research , 1979 .

[24]  Sheldon Rosenberg,et al.  Developments in Applied Psycholinguistics Research. , 1968 .

[25]  S. Blumstein,et al.  Semantic Facutation in Aphasia: Effects of Time and Expectancy , 1995, Journal of Cognitive Neuroscience.

[26]  B. Murdoch,et al.  Automatic and volitional semantic processing in aphasia , 1990, Brain and Language.

[27]  A. Caramazza On drawing inferences about the structure of normal cognitive systems from the analysis of patterns of impaired performance: The case for single-patient studies , 1986, Brain and Cognition.

[28]  S. Blumstein The neurobiology of the sound structure of language. , 1995 .