Monoclonal immunoglobulin and its related abnormalities in cases of plasma cell dyscrasia.

One hundred and twenty four cases of plasma cell dyscrasia (PCD) were investigated in terms of monoclonal protein and its related abnonnalities. Seventy nine cases of myeloma were compared with 45 cases of PCD without osteolytic myeloma. Low levels of background immunoglobulins and high proportions of marrow plasma cells were seen in myeloma cases. Among myeloma cases, G-myeloma or A-myeloma had high levels of total serum proteins and monoclonal proteins, in contrast to data of D-myeloma or myeloma with Bence Jones protein only.

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