mGluR5 protect astrocytes from ischemic damage in postnatal CNS white matter

[1]  Richard J. Edwards,et al.  Metabotropic Glutamate Receptors , 2015, The Journal of Biological Chemistry.

[2]  P. Stys,et al.  White matter injury: Ischemic and nonischemic , 2014, Glia.

[3]  R. Fern,et al.  Neurotransmitter signaling in white matter , 2014, Glia.

[4]  A. Butt,et al.  TASK-1 channels in oligodendrocytes: A role in ischemia mediated disruption , 2013, Neurobiology of Disease.

[5]  Todd A. Fiacco,et al.  Astrocytic group I mGluR-dependent potentiation of astrocytic glutamate and potassium uptake. , 2013, Journal of neurophysiology.

[6]  J. Guadagno,et al.  Role of metabotropic glutamate receptor 5 signaling and homer in oxygen glucose deprivation-mediated astrocyte apoptosis , 2013, Molecular Brain.

[7]  Qi Dong,et al.  mGluR1,5 activation protects cortical astrocytes and GABAergic neurons from ischemia-induced impairment , 2013, Neuroscience Research.

[8]  Chun-hua Liu,et al.  Up‐regulated GLT‐1 Resists Glutamate Toxicity and Attenuates Glutamate‐induced Calcium Loading in Cultured Neurocytes , 2013, Basic & clinical pharmacology & toxicology.

[9]  W. Huo,et al.  A sequential impairment of cortical astrocytes and GABAergic neurons during ischemia is improved by mGluR1,5 activation , 2013, Neurological Sciences.

[10]  Anil Kumar,et al.  Involvement of metabotropic glutamate receptor 5, AKT/PI3K Signaling and NF-κB pathway in methamphetamine-mediated increase in IL-6 and IL-8 expression in astrocytes , 2012, Journal of Neuroinflammation.

[11]  Z. Fei,et al.  The selective mGluR5 agonist CHPG protects against traumatic brain injury in vitro and in vivo via ERK and Akt pathway , 2011, International journal of molecular medicine.

[12]  F. Jensen,et al.  Developmental regulation of group I metabotropic glutamate receptors in the premature brain and their protective role in a rodent model of periventricular leukomalacia. , 2010, Neuron glia biology.

[13]  N. Hamilton,et al.  Axons and astrocytes release ATP and glutamate to evoke calcium signals in NG2‐glia , 2010, Glia.

[14]  Frank Kirchhoff,et al.  Mechanisms of ATP‐ and glutamate‐mediated calcium signaling in white matter astrocytes , 2008, Glia.

[15]  M. Salter,et al.  The Mechanisms of Acute Ischemic Injury in the Cell Processes of Developing White Matter Astrocytes , 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[16]  D. Rossi,et al.  Astrocyte metabolism and signaling during brain ischemia , 2007, Nature Neuroscience.

[17]  C. Shannon,et al.  GFP imaging of live astrocytes: regional differences in the effects of ischaemia upon astrocytes , 2007, Journal of anatomy.

[18]  J. Deitmer,et al.  The role of metabotropic glutamate receptors for the generation of calcium oscillations in rat hippocampal astrocytes in situ. , 2006, Cerebral cortex.

[19]  I. Bayazitov,et al.  Group I metabotropic glutamate receptors reduce excitotoxic injury and may facilitate neurogenesis , 2005, Neuropharmacology.

[20]  D. Attwell,et al.  NMDA receptors are expressed in oligodendrocytes and activated in ischaemia , 2005, Nature.

[21]  M. Salter,et al.  NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury , 2005, Nature.

[22]  R. Swanson,et al.  Ischemia‐induced programmed cell death in astrocytes , 2005, Glia.

[23]  M. Chesler,et al.  Role of Na+‐H+ and Na+‐Ca2+ exchange in hypoxia‐related acute astrocyte death , 2005, Glia.

[24]  A. Butt,et al.  Functions of optic nerve glia: axoglial signalling in physiology and pathology , 2004, Eye.

[25]  D. Kintner,et al.  Na-K-Cl Cotransporter-Mediated Intracellular Na+ Accumulation Affects Ca2+ Signaling in Astrocytes in an In Vitro Ischemic Model , 2004, The Journal of Neuroscience.

[26]  Natalie S. Allcock,et al.  Acute Ischemic Injury of Astrocytes Is Mediated by Na‐K‐Cl Cotransport and not Ca2+ Influx at a Key Point in White Matter Development , 2004, Journal of neuropathology and experimental neurology.

[27]  Eric Klann,et al.  Activation of the Phosphoinositide 3-kinase–akt–mammalian Target of Rapamycin Signaling Pathway Is Required for Metabotropic Glutamate Receptor-dependent Long-term Depression , 2022 .

[28]  P. Stys White matter injury mechanisms. , 2004, Current molecular medicine.

[29]  A. Butt,et al.  Evidence that perinatal and adult NG2-glia are not conventional oligodendrocyte progenitors and do not depend on axons for their survival , 2003, Molecular and Cellular Neuroscience.

[30]  J. Geurts,et al.  Altered expression patterns of group I and II metabotropic glutamate receptors in multiple sclerosis. , 2003, Brain : a journal of neurology.

[31]  F. Jensen,et al.  Calcium-permeable AMPA/kainate receptors mediate toxicity and preconditioning by oxygen-glucose deprivation in oligodendrocyte precursors , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[32]  R. Swanson,et al.  Astrocytes and Brain Injury , 2003, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[33]  A. El Manira,et al.  Signaling Mechanisms of Metabotropic Glutamate Receptor 5 Subtype and Its Endogenous Role in a Locomotor Network , 2002, The Journal of Neuroscience.

[34]  A. Butt,et al.  P2X and P2Y purinoreceptors mediate ATP-evoked calcium signalling in optic nerve glia in situ. , 2001, Cell calcium.

[35]  E. Aronica,et al.  Immunohistochemical localization of group I and II metabotropic glutamate receptors in control and amyotrophic lateral sclerosis human spinal cord: upregulation in reactive astrocytes , 2001, Neuroscience.

[36]  R. Sapolsky,et al.  Differential Sensitivity of Murine Astrocytes and Neurons from Different Brain Regions to Injury , 2001, Experimental Neurology.

[37]  M. Chesler,et al.  Calcium dependence of rapid astrocyte death induced by transient hypoxia, acidosis, and extracellular ion shifts , 2001, Glia.

[38]  J. Xuereb,et al.  Activated astrocytes in areas of kainate-induced neuronal injury upregulate the expression of the metabotropic glutamate receptors 2/3 and 5 , 2001, Experimental Brain Research.

[39]  R. Dempsey,et al.  Neuroprotection by group I metabotropic glutamate receptor antagonists in forebrain ischemia of gerbil , 2000, Neuroscience Letters.

[40]  J. Kuo,et al.  Gliotoxic Action of Glutamate on Cultured Astrocytes , 2000, Journal of neurochemistry.

[41]  R. Balázs,et al.  Expression of metabotropic glutamate receptor 5 is increased in astrocytes after kainate‐induced epileptic seizures , 2000, Glia.

[42]  Shuxin Li,et al.  Mechanisms of Ionotropic Glutamate Receptor-Mediated Excitotoxicity in Isolated Spinal Cord White Matter , 2000, The Journal of Neuroscience.

[43]  H. Kimelberg,et al.  Metabotropic glutamate receptors in acutely isolated hippocampal astrocytes: Developmental changes of mGluR5 mRNA and functional expression , 2000, Glia.

[44]  H. Kimelberg,et al.  mGluR3 and mGluR5 are the predominant metabotropic glutamate receptor mRNAs expressed in hippocampal astrocytes acutely isolated from young rats , 1999, Journal of neuroscience research.

[45]  K. McCarthy,et al.  Mature hippocampal astrocytes exhibit functional metabotropic and ionotropic glutamate receptors in situ , 1999, Glia.

[46]  K. Reymann,et al.  Protective effect of group I metabotropic glutamate receptor activation against hypoxic/hypoglycemic injury in rat hippocampal slices: timing and involvement of protein kinase C , 1999, Neuropharmacology.

[47]  G. Silvaa,et al.  Group I and II metabotropic glutamate receptor expression in cultured rat spinal cord astrocytes , 1999 .

[48]  R. Fern Intracellular Calcium and Cell Death during Ischemia in Neonatal Rat White Matter Astrocytes In Situ , 1998, The Journal of Neuroscience.

[49]  D. Watanabe,et al.  Glutamate receptors: brain function and signal transduction 1 Published on the World Wide Web on 21 October 1997. 1 , 1998, Brain Research Reviews.

[50]  Tullio Pozzan,et al.  Prostaglandins stimulate calcium-dependent glutamate release in astrocytes , 1998, Nature.

[51]  S. Nakanishi,et al.  The Metabotropic Glutamate Receptor mGluR5 Induces Calcium Oscillations in Cultured Astrocytes via Protein Kinase C Phosphorylation , 1997, Journal of neurochemistry.

[52]  T. Pozzan,et al.  Intracellular Calcium Oscillations in Astrocytes: A Highly Plastic, Bidirectional Form of Communication between Neurons and Astrocytes In Situ , 1997, The Journal of Neuroscience.

[53]  U. Heinemann,et al.  Cholecystokinin activates CCKB-receptor-mediated Ca-signaling in hippocampal astrocytes. , 1997, Journal of neurophysiology.

[54]  Shigetada Nakanishi,et al.  Control of calcium oscillations by phosphorylation of metabotropic glutamate receptors , 1996, Nature.

[55]  M. Memo,et al.  Activation of Multiple Metabotropic Glutamate Receptor Subtypes Prevents NMDA‐induced Excitotoxicity in Rat Hippocampal Slices , 1996, The European journal of neuroscience.

[56]  V. Gallo,et al.  AMPA receptors shape Ca2+ responses in cortical oligodendrocyte progenitors and CG‐4 cells , 1995, Journal of neuroscience research.

[57]  M. Berry,et al.  Astrocyte associations with nodes of Ranvier: ultrastructural analysis of HRP-filled astrocytes in the mouse optic nerve , 1994, Journal of neurocytology.

[58]  K. McCarthy,et al.  Pharmacologically-distinct subsets of astroglia can be identified by their calcium response to neuroligands , 1991, Neuroscience.

[59]  G H Sato,et al.  Growth of a rat neuroblastoma cell line in serum-free supplemented medium. , 1979, Proceedings of the National Academy of Sciences of the United States of America.