A conditional mouse model of synovial sarcoma: insights into a myogenic origin.

[1]  M. Capecchi,et al.  Motoneurons and oligodendrocytes are sequentially generated from neural stem cells but do not appear to share common lineage-restricted progenitors in vivo , 2006, Development.

[2]  P. Meltzer,et al.  Gene expression profiling of human sarcomas: insights into sarcoma biology. , 2005, Cancer research.

[3]  Neil Sebire,et al.  A molecular map of mesenchymal tumors , 2005, Genome Biology.

[4]  N. Segal,et al.  Analysis of hypoxia-related gene expression in sarcomas and effect of hypoxia on RNA interference of vascular endothelial cell growth factor A. , 2005, Cancer research.

[5]  J. Epstein,et al.  Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivatives. , 2005, Developmental biology.

[6]  J. Mesirov,et al.  An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis , 2005, Nature Genetics.

[7]  C. Chanoine,et al.  Myogenic regulatory factors: Redundant or specific functions? Lessons from Xenopus , 2004, Developmental Dynamics.

[8]  M. Capecchi,et al.  Pax 3 : Fkhr interferes with embryonic Pax 3 and Pax 7 function : implications for alveolar rhabdomyosarcoma cell of origin , 2004 .

[9]  Benjamin R. Arenkiel,et al.  Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function. , 2004, Genes & development.

[10]  T. Braun,et al.  Pax7 directs postnatal renewal and propagation of myogenic satellite cells but not their specification , 2004, The EMBO journal.

[11]  C. Cooper,et al.  Conserved SNH domain of the proto-oncoprotein SYT interacts with components of the human chromatin remodelling complexes, while the QPGY repeat domain forms homo-oligomers , 2003, Oncogene.

[12]  L. Guillou,et al.  Monophasic Fibrous and Poorly Differentiated Synovial Sarcoma: Immunohistochemical Reassessment of 60 t(X;18)(SYT-SSX)-Positive Cases , 2002, The American journal of surgical pathology.

[13]  Andrew P McMahon,et al.  Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. , 2002, Developmental biology.

[14]  D. Botstein,et al.  For Personal Use. Only Reproduce with Permission from the Lancet Publishing Group , 2022 .

[15]  Shi Tang,et al.  A cre/loxP‐deleter transgenic line in mouse strain 129S1/SvImJ , 2002, Genesis.

[16]  R. Scolyer Enzinger and Weiss's Soft Tissue Tumors: Fourth Edition , 2002 .

[17]  C. Emerson,et al.  Myogenic regulatory factors and the specification of muscle progenitors in vertebrate embryos. , 2002, Annual review of cell and developmental biology.

[18]  M. Ladanyi,et al.  Impact of SYT-SSX fusion type on the clinical behavior of synovial sarcoma: a multi-institutional retrospective study of 243 patients. , 2002, Cancer research.

[19]  O. Larsson,et al.  Clinical impact of molecular and cytogenetic findings in synovial sarcoma , 2001, Genes, chromosomes & cancer.

[20]  G. Merkx,et al.  Mapping and characterization of the mouse and human SS 18 genes , two human SS 18-like genes and a mouse Ss 18 pseudogene , 2001 .

[21]  J. Goldblum,et al.  Enzinger and Weiss's Soft Tissue Tumors , 2001 .

[22]  Shankar Srinivas,et al.  Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus , 2001, BMC Developmental Biology.

[23]  H. Sonobe,et al.  Analysis of transforming activity of human synovial sarcoma-associated chimeric protein SYT-SSX1 bound to chromatin remodeling factor hBRM/hSNF2α , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[24]  A. V. van Kessel,et al.  Molecular mechanisms underlying human synovial sarcoma development , 2001, Genes, chromosomes & cancer.

[25]  F. Collin,et al.  Detection of the synovial sarcoma translocation t(X;18) (SYT;SSX) in paraffin-embedded tissues using reverse transcriptase-polymerase chain reaction: a reliable and powerful diagnostic tool for pathologists. A molecular analysis of 221 mesenchymal tumors fixed in different fixatives. , 2001, Human pathology.

[26]  M. Ladanyi,et al.  Contribution of molecular genetic data to the classification of sarcomas. , 2000, Human pathology.

[27]  A. V. van Kessel,et al.  Delineation of the protein domains responsible for SYT, SSX, and SYT-SSX nuclear localization. , 2000, Experimental cell research.

[28]  J. Epstein,et al.  Pax3 and vertebrate development. , 2000, Methods in molecular biology.

[29]  J. Mesirov,et al.  Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. , 1999, Science.

[30]  G. Nilsson,et al.  A novel fusion gene, SYT-SSX4, in synovial sarcoma. , 1999, Journal of the National Cancer Institute.

[31]  D. Brett,et al.  Functional domains of the SYT and SYT-SSX synovial sarcoma translocation proteins and co-localization with the SNF protein BRM in the nucleus. , 1999, Human molecular genetics.

[32]  Philippe Soriano Generalized lacZ expression with the ROSA26 Cre reporter strain , 1999, Nature Genetics.

[33]  F. Lim,et al.  A KRAB-related domain and a novel transcription repression domain in proteins encoded by SSX genes that are disrupted in human sarcomas , 1998, Oncogene.

[34]  K. Nagashima,et al.  Diagnosis of Synovial Sarcoma with the Reverse Transcriptase‐Polymerase Chain Reaction: Analyses of 84 Soft Tissue and Bone Tumors , 1998, Diagnostic molecular pathology : the American journal of surgical pathology, part B.

[35]  M. Ladanyi,et al.  SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma. , 1998, The New England journal of medicine.

[36]  H. Hibshoosh,et al.  Immunohistochemical and molecular genetic approaches to soft tissue tumor diagnosis: a primer. , 1997, Seminars in oncology.

[37]  Özlem Türeci,et al.  SSX: A multigene family with several members transcribed in normal testis and human cancer , 1997, International journal of cancer.

[38]  L A Herzenberg,et al.  Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[39]  U. Zechner,et al.  Isolation and characterization of the mouse homolog of SYT, a gene implicated in the development of human synovial sarcomas. , 1996, Oncogene.

[40]  J. Fletcher,et al.  Detection of chromosome 18 rearrangement in synovial sarcoma by fluorescence in situ hybridization. , 1995, Cancer genetics and cytogenetics.

[41]  B. de Leeuw,et al.  Identification of two alternative fusion genes, SYT-SSX1 and SYT-SSX2, in t(X;18)(p11.2;q11.2)-positive synovial sarcomas. , 1995, Human molecular genetics.

[42]  B. Gusterson,et al.  Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel‐associated box in human synovial sarcoma. , 1995, The EMBO journal.

[43]  C. Fisher,et al.  Synovial sarcomas lack synovial differentiation , 1995, Histopathology.

[44]  Genes, chromosomes & cancer , 1995 .

[45]  P. Cin,et al.  Two categories of synovial sarcoma defined by divergent chromosome translocation breakpoints in Xp11.2, with implications for the histologic sub-classification of synovial sarcoma. , 1995, Cytogenetics and cell genetics.

[46]  C. Cooper,et al.  Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma , 1994, Nature Genetics.

[47]  E. van den Berg,et al.  Distinct Xp11.2 breakpoint regions in synovial sarcoma revealed by metaphase and interphase FISH: relationship to histologic subtypes. , 1994, Cancer genetics and cytogenetics.

[48]  R. Jackson,et al.  The novel mechanism of initiation of picornavirus RNA translation. , 1990, Trends in biochemical sciences.

[49]  P. Gruss,et al.  The murine paired box gene, Pax7, is expressed specifically during the development of the nervous and muscular system , 1990, Mechanisms of Development.

[50]  E. Wimmer,et al.  Cap-independent translation of encephalomyocarditis virus RNA: structural elements of the internal ribosomal entry site and involvement of a cellular 57-kD RNA-binding protein. , 1990, Genes & development.

[51]  B. Reeves,et al.  A consistent chromosome translocation in synovial sarcoma. , 1987, Cancer genetics and cytogenetics.

[52]  C. Fisher Synovial sarcoma: ultrastructural and immunohistochemical features of epithelial differentiation in monophasic and biphasic tumors. , 1986, Human pathology.

[53]  P. Cin,et al.  Translocations involving the X chromosome in solid tumors: presentation of two sarcomas with t(X;18)(q13;p11). , 1986, Cancer genetics and cytogenetics.