LXR-Dependent Gene Expression Is Important for Macrophage Survival and the Innate Immune Response

[1]  Ryan M. O’Connell,et al.  Type I Interferon Production Enhances Susceptibility to Listeria monocytogenes Infection , 2004, The Journal of experimental medicine.

[2]  William A. Boisvert,et al.  Transcriptional Repression of Atherogenic Inflammation: Modulation by PPARδ , 2003, Science.

[3]  G. Cheng,et al.  Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism. , 2003, Molecular cell.

[4]  D. Mangelsdorf,et al.  Liver X receptor signaling pathways in cardiovascular disease. , 2003, Molecular endocrinology.

[5]  G. Núñez,et al.  Cell death and immunity: NODs: intracellular proteins involved in inflammation and apoptosis , 2003, Nature Reviews Immunology.

[6]  Takashi Yamamoto,et al.  AIM inhibits apoptosis of T cells and NKT cells in Corynebacterium-induced granuloma formation in mice. , 2003, The American journal of pathology.

[7]  D. Rader,et al.  Lipolysis of triglyceride-rich lipoproteins generates PPAR ligands: Evidence for an antiinflammatory role for lipoprotein lipase , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[8]  E. Unanue,et al.  MyD88-Dependent but Toll-Like Receptor 2-Independent Innate Immunity to Listeria: No Role for Either in Macrophage Listericidal Activity1 , 2002, The Journal of Immunology.

[9]  Aldons J. Lusis,et al.  Identification of macrophage liver X receptors as inhibitors of atherosclerosis , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[10]  R. Walczak,et al.  Autoregulation of the Human Liver X Receptor α Promoter , 2001, Molecular and Cellular Biology.

[11]  Makio Kobayashi,et al.  Association of AIM, a Novel Apoptosis Inhibitory Factor, with Hepatitis via Supporting Macrophage Survival and Enhancing Phagocytotic Function of Macrophages* , 2001, The Journal of Biological Chemistry.

[12]  Christopher K. Glass,et al.  Atherosclerosis The Road Ahead , 2001, Cell.

[13]  D. Mangelsdorf,et al.  LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes. , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[14]  P. Edwards,et al.  Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[15]  K. Fettucciari,et al.  Group B Streptococcus Induces Apoptosis in Macrophages1 , 2000, The Journal of Immunology.

[16]  D. Mangelsdorf,et al.  Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers. , 2000, Science.

[17]  E. Unanue,et al.  Immunity to Listeria infection. , 2000, Current opinion in immunology.

[18]  T. V. van Berkel,et al.  Hepatic and extrahepatic scavenger receptors: function in relation to disease. , 2000, Arteriosclerosis, thrombosis, and vascular biology.

[19]  M. Díaz-Guerra,et al.  Inhibition of IκB Kinase and IκB Phosphorylation by 15-Deoxy-Δ12,14-Prostaglandin J2 in Activated Murine Macrophages , 2000, Molecular and Cellular Biology.

[20]  A. Aruffo,et al.  Molecular cloning, genomic organization and cell‐binding characteristicsof mouse Spα , 2000, Immunology.

[21]  M. Naito,et al.  Increased Susceptibility of  Thymocytes to Apoptosis in Mice Lacking AIM, a Novel Murine Macrophage-derived Soluble Factor Belonging to the Scavenger Receptor Cysteine-rich Domain Superfamily , 1999, The Journal of experimental medicine.

[22]  S. Gordon,et al.  Regulation and functional involvement of macrophage scavenger receptor MARCO in clearance of bacteria in vivo. , 1999, Journal of immunology.

[23]  R. Hammer,et al.  Cholesterol and Bile Acid Metabolism Are Impaired in Mice Lacking the Nuclear Oxysterol Receptor LXRα , 1998, Cell.

[24]  R. Evans,et al.  PPARγ Promotes Monocyte/Macrophage Differentiation and Uptake of Oxidized LDL , 1998, Cell.

[25]  Christopher K. Glass,et al.  The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation , 1998, Nature.

[26]  H. Hilbi,et al.  The interleukin 1beta-converting enzyme, caspase 1, is activated during Shigella flexneri-induced apoptosis in human monocyte-derived macrophages , 1997, Infection and immunity.

[27]  J. W. Conlan,et al.  Murine listeriosis as a model of antimicrobial defense , 1997, Immunological reviews.

[28]  G. Puzo,et al.  Differential induction of apoptosis by virulent Mycobacterium tuberculosis in resistant and susceptible murine macrophages: role of nitric oxide and mycobacterial products. , 1997, Journal of immunology.

[29]  Yukiko Kurihara,et al.  A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection , 1997, Nature.

[30]  U. Francke,et al.  Molecular Cloning, Mapping to Human Chromosome 1 q21-q23, and Cell Binding Characteristics of Spα, a New Member of the Scavenger Receptor Cysteine-rich (SRCR) Family of Proteins* , 1997, The Journal of Biological Chemistry.

[31]  Timothy M. Willson,et al.  Activation of the Nuclear Receptor LXR by Oxysterols Defines a New Hormone Response Pathway* , 1997, The Journal of Biological Chemistry.

[32]  D. Mangelsdorf,et al.  An oxysterol signalling pathway mediated by the nuclear receptor LXRα , 1996, Nature.

[33]  K. Timmis,et al.  Apoptosis of mouse dendritic cells is triggered by listeriolysin, the major virulence determinant of Listeria monocytogenes , 1996, Molecular microbiology.

[34]  I. Esparza.  [The function of macrophages]. , 1986, Medicina clinica.

[35]  D. Mangelsdorf,et al.  The role of orphan nuclear receptors in the regulation of cholesterol homeostasis. , 2000, Annual review of cell and developmental biology.