Mannose-6-phosphate regulates destruction of lipid-linked oligosaccharides

Mannose-6-phosphate is a common metabolite in glycoconjugate synthesis. In this study, it is revealed to do double duty as a second messenger-like signaling molecule, in a novel pathway that responds to HSV-1 stress to destroy host lipid–linked oligosaccharides otherwise used by the virus to generate glycoprotein components of its envelope.

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