PLACENTAL TRANSFER OF TUBOCURARINE

SUMMARY A case is reported in which tubocurarine crossed the placental barrier and paralyzed a 28-week foetus. The mother was under treatment for status epilepticus. The authors review the present evidence for the transplacental passage of tubocurarine and suggest that previous work may not represent the situation accurately. Reference is made to a further case which also suggests transplacental passage of tubocurarine, this time in the first trimester of pregnancy.