Blood-Brain Barrier Permeation: Molecular Parameters Governing Passive Diffusion
暂无分享,去创建一个
[1] G. Zaccai,et al. Neutron diffraction studies on selectively deuterated phospholipid bilayers , 1978, Nature.
[2] D. D. Perrin,et al. pKa prediction for organic acids and bases , 1981 .
[3] C. Niemegeers,et al. Domperidone, a novel and safe gastrokinetic anti-nauseant for the treatment of dyspepsia and vomiting. , 1978, Arzneimittel-Forschung.
[4] D. Marsh. Lateral pressure in membranes. , 1996, Biochimica et biophysica acta.
[5] J. Seelig,et al. Lipid conformation in model membranes and biological membranes , 1980, Quarterly Reviews of Biophysics.
[6] A. Seelig. A general pattern for substrate recognition by P-glycoprotein. , 1998, European journal of biochemistry.
[7] A. Seelig,et al. Local anesthetics and pressure: a comparison of dibucaine binding to lipid monolayers and bilayers. , 1987, Biochimica et biophysica acta.
[8] J. Seelig,et al. Cholesterol-induced rod-like motion of fatty acyl chains in lipid bilayers a deuterium magnetic resonance study. , 1976, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.
[9] J. Drewe,et al. Transport of clonidine across cultured brain microvessel endothelial cells. , 1997, The Journal of pharmacology and experimental therapeutics.
[10] D Mackay,et al. A novel method for measuring membrane-water partition coefficients of hydrophobic organic chemicals: comparison with 1-octanol-water partitioning. , 1988, Journal of Pharmacy and Science.
[11] A. Blume,et al. Thermodynamics of Micelle Formation as a Function of Temperature: A High Sensitivity Titration Calorimetry Study , 1995 .
[12] Martindale.,et al. THE EXTRA PHARMACOPOEIA , 1937 .
[13] A. Tsuji,et al. Physicochemical Properties of β-Lactam Antibiotics: Oil-Water Distribution , 1977 .
[14] S. McLaughlin,et al. The electrostatic properties of membranes. , 1989, Annual review of biophysics and biophysical chemistry.
[15] T R Stouch,et al. Solute diffusion in lipid bilayer membranes: an atomic level study by molecular dynamics simulation. , 1993, Biochemistry.
[16] J. Heykants,et al. Loperamide (R 18 553), a novel type of antidiarrheal agent. Part 5: the pharmacokinetics of loperamide in rats and man. , 1974, Arzneimittel-Forschung.
[17] L. Mayer,et al. Influence of ion gradients on the transbilayer distribution of dibucaine in large unilamellar vesicles. , 1988, Biochemistry.
[18] J. Seelig,et al. Nonclassical hydrophobic effect in membrane binding equilibria. , 1991, Biochemistry.
[19] M. J. Rosen. Surfactants and Interfacial Phenomena , 1978 .
[20] J. Seelig,et al. Peptide binding to lipid bilayers. Nonclassical hydrophobic effect and membrane-induced pK shifts. , 1992, Biochemistry.
[21] B. Roelofsen,et al. Relation between various phospholipase actions on human red cell membranes and the interfacial phospholipid pressure in monolayers. , 1975, Biochimica et biophysica acta.
[22] R. Macdonald. THE RELATIONSHIP AND INTERACTIONS BETWEEN LIPID BILAYERS VESICLES AND LIPID MONOLAYERS AT THE AIR/WATER INTERFACE , 1996 .
[23] H. M. Bender,et al. A pharmacological profile of the novel, peripherally‐selective k‐opioid receptor agonist, EMD 61753 , 1994, British journal of pharmacology.
[24] D. Marsh,et al. Phospholipid Bilayers: Physical Principles and Models , 1987 .
[25] R. Laruel,et al. [Research on the benzofuran series. XXXVII. Comparative study of transit and metabolism of amiodarone in different species of animals and humans]. , 1969, Archives internationales de pharmacodynamie et de therapie.
[26] K. Chan,et al. Metabolic disposition of terfenadine in laboratory animals. , 1982, Arzneimittel-Forschung.
[27] Bernard Testa,et al. Lipophilicity and hydrogen-bonding capacity of H1-antihistaminic agents in relation to their central sedative side-effects , 1994 .
[28] G van Meer,et al. Lipid sorting in epithelial cells. , 1988, Biochemistry.
[29] V. Schuermans,et al. Loperamide (R 18 553), a novel type of antidiarrheal agent. Part 6: Clinical pharmacology. Placebo-controlled comparison of the constipating activity and safety of loperamide, diphenoxylate and codeine in normal volunteers. , 1974, Arzneimittel-Forschung.
[30] R. Lewis,et al. Analgesic and mechanistic evaluation of spiradoline, a potent kappa opioid. , 1988, The Journal of pharmacology and experimental therapeutics.
[31] R. Kaliszan. High Performance Liquid Chromatographic Methods and Procedures of Hydrophobicity Determination , 1990 .
[32] A. Sedman,et al. Diuretic Effects, Pharmacokinetics, and Safety of a New Centrally Acting Kappa‐Opioid Agonist (CI‐977) in Humans , 1994, Journal of clinical pharmacology.
[33] S. McLaughlin,et al. Effect of monolayer surface pressure on the activities of phosphoinositide-specific phospholipase C-beta 1, -gamma 1, and -delta 1. , 1994, Biochemistry.
[34] J. Seelig,et al. Deuterium magnetic resonance studies of phospholipid bilayers. , 1974, Biochemical and biophysical research communications.
[35] C. Pidgeon,et al. Immobilized Artificial Membranes — screens for drug membrane interactions , 1997 .
[36] C. Altenbach,et al. Binding of the lipophilic cation tetraphenylphosphonium to phosphatidylcholine , 1985 .
[37] C. Pidgeon,et al. Membrane partition coefficients chromatographically measured using immobilized artificial membrane surfaces. , 1995, Analytical chemistry.
[38] M. Wenk,et al. Octyl-beta-D-glucopyranoside partitioning into lipid bilayers: thermodynamics of binding and structural changes of the bilayer. , 1997, Biophysical journal.
[39] J. Overbeek,et al. Physical chemical studies of short-chain lecithin homologues. 3. Phase separation and light scattering studies on aqueous dioctanoyllecithin solutions. , 1974, Biophysical chemistry.
[40] A. Seelig,et al. A method to determine the ability of drugs to diffuse through the blood-brain barrier. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[41] D. W. Newton,et al. pKa Values of Medicinal Compounds in Pharmacy Practice , 1978 .