Synthesis and activity of 4,5-diarylimidazoles as human CB1 receptor inverse agonists.
暂无分享,去创建一个
J. Chen | L. V. D. van der Ploeg | L. Shearman | G. Doss | T. Fong | X. Tong | S. Mills | C. Plummer | Junying Wang | A. Strack | M. Schaeffer | D. Stribling | P. Finke | J. Lao | Chun-Pyn Shen | Jing Chen | Julie Z. Lao
[1] J. Chen,et al. Synthesis and SAR of 5,6-diarylpyridines as human CB1 inverse agonists. , 2005, Bioorganic & medicinal chemistry letters.
[2] P. Soubrié,et al. Anti-obesity effect of SR141716, a CB1 receptor antagonist, in diet-induced obese mice. , 2003, American journal of physiology. Regulatory, integrative and comparative physiology.
[3] A. Izzo,et al. Cannabinoids for gastrointestinal diseases: potential therapeutic applications , 2003, Expert opinion on investigational drugs.
[4] K. Flegal,et al. Prevalence and trends in obesity among US adults, 1999-2000. , 2002, JAMA.
[5] Á. Pazos,et al. Cannabinoid receptor antagonism and inverse agonism in response to SR141716A on cAMP production in human and rat brain. , 2002, European journal of pharmacology.
[6] William J Welsh,et al. Molecular interaction of the antagonist N-(piperidin-1-yl)-5-(4-chlorophenyl)-1- (2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide with the CB1 cannabinoid receptor. , 2002, Journal of medicinal chemistry.
[7] R. Pertwee. Cannabinoid receptor ligands: clinical and neuropharmacological considerations, relevant to future drug discovery and development , 2000, Expert opinion on investigational drugs.
[8] M. Rinaldi-Carmona,et al. The development of cannabinoid antagonists. , 1999, Current medicinal chemistry.
[9] John C. Lee,et al. Chapter 20. Pharmacology of Cannabinoid Receptor Agonists and Antagonists , 1999 .
[10] P. Casellas,et al. A Selective Inverse Agonist for Central Cannabinoid Receptor Inhibits Mitogen-activated Protein Kinase Activation Stimulated by Insulin or Insulin-like Growth Factor 1 , 1997, The Journal of Biological Chemistry.
[11] R. Pertwee. Pharmacology of cannabinoid CB1 and CB2 receptors. , 1997, Pharmacology & therapeutics.
[12] K. Mackie,et al. Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors. , 1995, Molecular pharmacology.
[13] Chang Kiu Lee,et al. Condensation reactions of aryl acyloins with ureas in ethylene glycol , 1994 .
[14] P. Soubrié,et al. SR141716A, a potent and selective antagonist of the brain cannabinoid receptor , 1994, FEBS letters.
[15] M. Johnson,et al. Enhancement of brain [3H]flunitrazepam binding and analgesic activity of synthetic cannabimimetics. , 1985, European journal of pharmacology.
[16] I. I. Brekhman,et al. Effect of eleutherococcus on alarm-phase of stress. , 1969, Life sciences.
[17] R. Gompper,et al. Formamid‐Reaktionen, XII. Alkylierungs‐ und Acylierungsreaktionen an Formamid: Tris‐formylamino‐methan , 1959 .