Mass Spectrometry in the Home and Garden

AbstractIdentification of active components in a variety of chemical products used directly by consumers is described at both trace and bulk levels using mass spectrometry. The combination of external ambient ionization with a portable mass spectrometer capable of tandem mass spectrometry provides high chemical specificity and sensitivity as well as allowing on-site monitoring. These experiments were done using a custom-built portable ion trap mass spectrometer in combination with the ambient ionization methods of paper spray, leaf spray, and low temperature plasma ionization. Bactericides, garden chemicals, air fresheners, and other products were examined. Herbicide applied to suburban lawns was detected in situ on single leaves 5 d after application. Graphical Abstractᅟ

[1]  Zheng Ouyang,et al.  Mini 12, Miniature Mass Spectrometer for Clinical and Other Applications—Introduction and Characterization , 2014, Analytical chemistry.

[2]  K. Rogers,et al.  Eliminating false positive C4 sugar tests on New Zealand Manuka honey. , 2010, Rapid communications in mass spectrometry : RCM.

[3]  Matthew A Kirleis,et al.  Autonomous in situ analysis and real-time chemical detection using a backpack miniature mass spectrometer: concept, instrumentation development, and performance. , 2014, Analytical chemistry.

[4]  R. Cooks,et al.  Desorption electrospray ionization and other ambient ionization methods: current progress and preview. , 2010, The Analyst.

[5]  V. Wysocki,et al.  Paper spray ionization of noncovalent protein complexes. , 2014, Analytical chemistry.

[6]  R. Cooks,et al.  Analysis of pesticide residues by leaf spray mass spectrometry , 2012 .

[7]  R. Cooks,et al.  Performance of a low voltage ion trap , 2011 .

[8]  C. Simpson,et al.  The Use of MIMS-MS-MS in field locations as an on-line quantitative environmental monitoring technique for trace contaminants in air and water. , 2009, Journal of chromatographic science.

[9]  Ariel R. Muliadi,et al.  Spray mechanism in paper spray ionization , 2012 .

[10]  E. Krogh,et al.  Membrane-introduction mass spectrometry (MIMS) , 2011 .

[11]  L. Hammond,et al.  Re: Knapp DW, Peer WA, Conteh A, Diggs AR, Cooper BR, Glickman NW, et al. detection of herbicides in the urine of pet dogs following home lawn application. Sci Total Env 2013; 456-457: 34-41. , 2014, Science of the Total Environment.

[12]  P. H. Hemberger,et al.  Membrane introduction mass spectrometry: trends and applications. , 2000, Mass spectrometry reviews.

[13]  George T. Tsao,et al.  On-line monitoring with feedback control of bioreactors using a high ethanol tolerance yeast by membrane introduction mass spectrometry , 1995 .

[14]  C. Engelhard,et al.  Characteristics of low-temperature plasma ionization for ambient mass spectrometry compared to electrospray ionization and atmospheric pressure chemical ionization. , 2012, Analytical chemistry.

[15]  A. Lebedev.  Environmental mass spectrometry. , 2013, Annual review of analytical chemistry.

[16]  R. Beiras,et al.  Toxicity of Benzalkonium Chloride on Monoalgal Cultures and Natural Assemblages of Marine Phytoplankton , 2009 .

[17]  Zheng Ouyang,et al.  Low-temperature plasma probe for ambient desorption ionization. , 2008, Analytical chemistry.

[18]  Aleksandar R. Zeradjanin,et al.  Temperature-Dependent Dissolution of Polycrystalline Platinum in Sulfuric Acid Electrolyte , 2014, Electrocatalysis.

[19]  T. V. van Beek,et al.  Rapid analysis of Δ-9-tetrahydrocannabinol in hair using direct analysis in real time ambient ionization orbitrap mass spectrometry. , 2014, Rapid communications in mass spectrometry : RCM.

[20]  A. Boldyrev,et al.  Signal Enhancement in Electrospray Laser Desorption/Ionization Mass Spectrometry by Using a Black Oxide-Coated Metal Target and a Relatively Low Laser Fluence , 2013, European journal of mass spectrometry.

[21]  A. Venter,et al.  Mechanisms of real-time, proximal sample processing during ambient ionization mass spectrometry. , 2014, Analytical chemistry.

[22]  Zheng Ouyang,et al.  Breaking the pumping speed barrier in mass spectrometry: discontinuous atmospheric pressure interface. , 2008, Analytical chemistry.

[23]  M. Schlüter,et al.  Application of membrane inlet mass spectrometry for online and in situ analysis of methane in aquatic environments , 2008, Journal of the American Society for Mass Spectrometry.

[24]  Huanwen Chen,et al.  Direct assessment of phytochemicals inherent in plant tissues using extractive electrospray ionization mass spectrometry. , 2013, Journal of agricultural and food chemistry.

[25]  R. Cooks,et al.  Nucleophilic Addition of Nitrogen to Aryl Cations: Mimicking Titan Chemistry , 2013, Journal of The American Society for Mass Spectrometry.

[26]  Analytical Applications of Membranes , 2013 .

[27]  U. Karst,et al.  Ambient molecular imaging by laser ablation atmospheric pressure chemical ionization mass spectrometry. , 2013, Rapid communications in mass spectrometry : RCM.

[28]  R. Cole,et al.  Atmospheric Pressure Ionization Mass Spectrometry , 2006 .

[29]  R. Cooks,et al.  In vivo mass spectrometric determination of organic compounds in blood with a membrane probe. , 1987, Analytical chemistry.

[30]  Prabha Dwivedi,et al.  Mass spectrometry: recent advances in direct open air surface sampling/ionization. , 2013, Chemical reviews.

[31]  R. Cooks,et al.  Leaf spray: direct chemical analysis of plant material and living plants by mass spectrometry. , 2011, Analytical chemistry.

[32]  A. Murphy,et al.  Detection of herbicides in the urine of pet dogs following home lawn chemical application. , 2013, The Science of the total environment.

[33]  S. Bauer,et al.  Determination of volatile organic compounds at the parts per trillion level in complex aqueous matrices using membrane introduction mass spectrometry , 1994 .

[34]  Nicholas E. Manicke,et al.  Silica coated paper substrate for paper-spray analysis of therapeutic drugs in dried blood spots. , 2012, Analytical chemistry.

[35]  D. I. Carroll,et al.  Atmospheric pressure ionization mass spectrometry. Corona discharge ion source for use in a liquid chromatograph-mass spectrometer-computer analytical system , 1975 .

[36]  R Graham Cooks,et al.  Direct analysis of volatile organic compounds in human breath using a miniaturized cylindrical ion trap mass spectrometer with a membrane inlet. , 2002, Rapid communications in mass spectrometry : RCM.

[37]  R. Cooks,et al.  Mass Spectrometry Sampling Under Ambient Conditions with Desorption Electrospray Ionization , 2004, Science.