The MIP family of integral membrane channel proteins: sequence comparisons, evolutionary relationships, reconstructed pathway of evolution, and proposed functional differentiation of the two repeated halves of the proteins.

AbstractThe major intrinsic protein (MIP) of the bovine lens fiber cell membrane was the first member of the MIP family of proteins to be sequenced and characterized. It is probably a homotetramer with transmembrane channel activity that plays a role in lens biogenesis or maintenance. The polypeptide chain of each subunit may span the membrane six times, and both the N- and C-termini face the cell cytoplasm. Eighteen sequenced or partially sequenced proteins from bacteria, yeast, plants, and animals have now been shown to be members of the MIP family. These proteins appear to function in (1) metazoan development and neurogenesis (MIP and BIB), (2) water transport across the human erythrocyte membrane (ChIP), (3) communication between host plant cells and symbiotic nitrogen-fixing bacteria (NOD), (4) transport across the tonoplast membrane during plant seed development (α-TIP), (5) water stress-induced resistance to desiccation in plants (Wsi-TIP), (6) suppression of a genetic growth defect on fermentable ...

[1]  G. Zampighi,et al.  Properties of channels reconstituted from the major intrinsic protein of lens fiber membranes , 1990, The Journal of general physiology.

[2]  K. Chater,et al.  Structure and regulation of controlling sequences for the Streptomyces coelicolor glycerol operon. , 1988, Journal of molecular biology.

[3]  D. Verma,et al.  Topology and phosphorylation of soybean nodulin-26, an intrinsic protein of the peribacteroid membrane , 1992, The Journal of cell biology.

[4]  P. Lampe,et al.  A lens intercellular junction protein, MP26, is a phosphoprotein , 1986, The Journal of cell biology.

[5]  G. Zampighi,et al.  The structural organization and protein composition of lens fiber junctions , 1989, The Journal of cell biology.

[6]  P. Lampe,et al.  Phosphorylation of lens intrinsic membrane proteins by protein kinase C. , 1986, European journal of biochemistry.

[7]  M H Saier,et al.  Evolution of the MIP family of integral membrane transport proteins , 1991, Molecular microbiology.

[8]  H. Höfte,et al.  An intrinsic tonoplast protein of protein storage vacuoles in seeds is structurally related to a bacterial solute transporter (GIpF). , 1990, The Plant cell.

[9]  D. Bok,et al.  Conformational properties of the main intrinsic polypeptide (MIP26) isolated from lens plasma membranes. , 1987, Biochemistry.

[10]  A. Bairoch.  PROSITE: a dictionary of sites and patterns in proteins. , 1991, Nucleic acids research.

[11]  Douglas W. Smith.  A complete, yet flexible, system for DNA/protein sequence analysis using VAX/VMS computers , 1988, Comput. Appl. Biosci..

[12]  M. Chrispeels,et al.  Tonoplast-bound protein kinase phosphorylates tonoplast intrinsic protein. , 1992, Plant physiology.

[13]  N. A. Kent,et al.  Nucleotide and derived amino-acid sequence of the major intrinsic protein of rat eye-lens. , 1990, Nucleic acids research.

[14]  R. Doolittle,et al.  A simple method for displaying the hydropathic character of a protein. , 1982, Journal of molecular biology.

[15]  A. Verkman,et al.  Functional reconstitution of the isolated erythrocyte water channel CHIP28. , 1992, The Journal of biological chemistry.

[16]  M. Saier.  Evolution of permease diversity and energy-coupling mechanisms: an introduction. , 1990, Research in microbiology.

[17]  J. Xia,et al.  Hydrodynamic characterization of the major intrinsic protein from the bovine lens fiber membranes. Extraction in n-octyl-beta-D-glucopyranoside and evidence for a tetrameric structure. , 1990, The Journal of biological chemistry.

[18]  N. Sandal,et al.  Soybean nodulin 26 is homologous to the major intrinsic protein of the bovine lens fiber membrane. , 1988, Nucleic acids research.

[19]  M. A. Conkling,et al.  Root-specific genes from tobacco and Arabidopsis homologous to an evolutionarily conserved gene family of membrane channel proteins. , 1990, Nucleic acids research.

[20]  R. Doolittle,et al.  Nearest neighbor procedure for relating progressively aligned amino acid sequences. , 1990, Methods in enzymology.

[21]  T. Mizuno,et al.  Nucleotide sequence of the region encompassing the glpKF operon and its upstream region containing a bent DNA sequence of Escherichia coli. , 1989, Nucleic acids research.

[22]  L. Takemoto,et al.  Antisera to synthetic peptides of MIP26K as probes of changes in opaque vs. transparent regions within the same human cataractous lens. , 1987, Experimental eye research.

[23]  N. Sandal,et al.  Some nodulin and Nod proteins show similarity to specific animal proteins , 1990 .

[24]  G. Stacey,et al.  Calcium-dependent phosphorylation of symbiosome membrane proteins from nitrogen-fixing soybean nodules : evidence for phosphorylation of nodulin-26. , 1991, Plant physiology.

[25]  Peter Agre,et al.  Appearance of Water Channels in Xenopus Oocytes Expressing Red Cell CHIP28 Protein , 1992, Science.

[26]  D. Lipman,et al.  Improved tools for biological sequence comparison. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[27]  L. Takemoto,et al.  Changes in the major intrinsic polypeptide (MIP26K) during opacification of the Emory mouse lens. , 1988, Experimental eye research.

[28]  D. Verma.  Soybean Nodulin-26: A Channel Protein Conserved from Bacteria to Mammals , 1992 .

[29]  M. Pisano,et al.  Genomic cloning, complete nucleotide sequence, and structure of the human gene encoding the major intrinsic protein (MIP) of the lens. , 1991, Genomics.

[30]  P. Henderson.  Sugar transport proteins , 1991 .

[31]  J. Revel,et al.  The major intrinsic protein (MIP) of the bovine lens fiber membrane: Characterization and structure based on cDNA cloning , 1984, Cell.

[32]  D. Day,et al.  Protein phosphorylation stimulates the rate of malate uptake across the peribacteroid membrane of soybean nodules , 1991, FEBS letters.

[33]  P. Agre,et al.  Reconstitution of functional water channels in liposomes containing purified red cell CHIP28 protein. , 1992, Biochemistry.

[34]  R. Doolittle.  Of urfs and orfs : a primer on how to analyze devised amino acid sequences , 1986 .

[35]  M. Maeshima.  Characterization of the major integral protein of vacuolar membrane. , 1992, Plant physiology.

[36]  C. -. Cheng,et al.  Characterization of cis-acting sequences regulating root-specific gene expression in tobacco. , 1991, The Plant cell.

[37]  E. Herman,et al.  Vegetative and Seed-Specific Forms of Tonoplast Intrinsic Protein in the Vacuolar Membrane of Arabidopsis thaliana. , 1992, Plant physiology.

[38]  C. Maurel,et al.  The vacuolar membrane protein gamma‐TIP creates water specific channels in Xenopus oocytes. , 1993, The EMBO journal.

[39]  N. A. Kent,et al.  Homology of MIP26 to Nod26. , 1988, Nucleic acids research.

[40]  M. Maiden,et al.  Homologous sugar transport proteins in Escherichia coli and their relatives in both prokaryotes and eukaryotes. , 1990, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[41]  J. Craig Venter,et al.  Sequence identification of 2,375 human brain genes , 1992, Nature.

[42]  K. Shinozaki,et al.  Molecular Cloning and Characterization of 9 cDNAs for Genes That Are Responsive to Desiccation in Arabidopsis thaliana: SequenceAnalysis of One cDNA Clone That Encodes a Putative Transmembrane Channel Protein , 1992 .

[43]  L. Beijer,et al.  Glycerol catabolism in Bacillus subtilis: nucleotide sequence of the genes encoding glycerol kinase (glpK) and glycerol-3-phosphate dehydrogenase (glpD). , 1990, Journal of general microbiology.

[44]  M. Saier,et al.  A common ancestor for bovine lens fiber major intrinsic protein, soybean nodulin-26 protein, and E. coli glycerol facilitator , 1990, Cell.

[45]  Y. Jan,et al.  Similarity of the product of the Drosophila neurogenic gene big brain to transmembrane channel proteins , 1990, Nature.

[46]  C. Macleod,et al.  Mammalian integral membrane receptors are homologous to facilitators and antiporters of yeast, fungi, and eubacteria , 1993, Protein science : a publication of the Protein Society.

[47]  P. Agre,et al.  Erythrocyte Mr 28,000 transmembrane protein exists as a multisubunit oligomer similar to channel proteins. , 1991, The Journal of biological chemistry.

[48]  R F Doolittle,et al.  Progressive alignment and phylogenetic tree construction of protein sequences. , 1990, Methods in enzymology.

[49]  P. Agre,et al.  Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: member of an ancient channel family. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[50]  M. Saier,et al.  A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport. , 1993, Trends in biochemical sciences.

[51]  D. Ludevid,et al.  The Expression Pattern of the Tonoplast Intrinsic Protein gamma-TIP in Arabidopsis thaliana Is Correlated with Cell Enlargement. , 1992, Plant physiology.

[52]  K. Agata,et al.  Partial amino acid sequence of the major intrinsic protein (MIP) of the chicken lens deduced from the nucleotide sequence of a cDNA clone. , 1990, Experimental eye research.

[53]  C. Slaughter,et al.  Adenylyl cyclase amino acid sequence: possible channel- or transporter-like structure. , 1989, Science.

[54]  James E. Hall,et al.  Does MIP play a role in cell–cell communication? , 1993 .

[55]  Y. Jan,et al.  Tracing the roots of ion channels , 1992, Cell.

[56]  J. Devereux,et al.  A comprehensive set of sequence analysis programs for the VAX , 1984, Nucleic Acids Res..

[57]  P. Maloney.  A consensus structure for membrane transport. , 1990, Research in microbiology.

[58]  G. Heijne.  Membrane protein structure prediction. Hydrophobicity analysis and the positive-inside rule. , 1992, Journal of molecular biology.

[59]  C. Weaver,et al.  Determination of the site of phosphorylation of nodulin 26 by the calcium-dependent protein kinase from soybean nodules. , 1992, Biochemistry.

[60]  E. Lin,et al.  Substrate specificity and transport properties of the glycerol facilitator of Escherichia coli , 1980, Journal of bacteriology.

[61]  M. Saier,et al.  Transport proteins in bacteria: common themes in their design. , 1992, Science.

[62]  I. Paulsen,et al.  Membrane transport proteins: implications of sequence comparisons. , 1992, Current opinion in cell biology.

[63]  T. Mizuno,et al.  Nucleotide sequence of the fabE gene and flanking regions containing a bent DNA sequence of Escherichia coli. , 1989, Nucleic acids research.

[64]  F. Zimmermann,et al.  A yeast homologue of the bovine lens fibre MIP gene family complements the growth defect of a Saccharomyces cerevisiae mutant on fermentable sugars but not its defect in glucose‐induced RAS‐mediated cAMP signalling. , 1991, The EMBO journal.

[65]  L. Takemoto,et al.  Major intrinsic polypeptide (MIP26K) from human lens membrane: characterization of low-molecular-weight forms in the aging human lens. , 1986, Experimental eye research.

[66]  M H Saier,et al.  The mitochondrial carrier family of transport proteins: structural, functional, and evolutionary relationships. , 1993, Critical reviews in biochemistry and molecular biology.

[67]  M. Saier,et al.  Families and superfamilies of transport proteins common to prokaryotes and eukaryotes , 1991 .

[68]  W. Bockelmann,et al.  Molecular cloning and sequence analysis of the X-prolyl dipeptidyl aminopeptidase gene from Lactococcus lactis subsp. cremoris , 1991, Applied and environmental microbiology.

[69]  P. Henderson.  The homologous glucose transport proteins of prokaryotes and eukaryotes. , 1990, Research in microbiology.