NAN-190: an arylpiperazine analog that antagonizes the stimulus effects of the 5-HT1A agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT).

In order to determine whether NAN 190 might serve as a 5-HT 1A antagonist, it was evaluated in rats trained to discriminate 8-OH-DPAT HBr from saline in a 2-lever operant procedure