Control of Polymerization Processes

Automation and advanced control of polymerization reactors constitute problems of paramount importance in the polymerization field, given the inherent complexity of most polymerization processes, allowing for safer and more stable operations, higher process productivities, and more secure environmental performance of these processes. For this reason, the present article provides an overview regarding the main subjects discussed in the literature of polymerization control. Particularly, this study highlights some classical polymerization control problems, describing some of the techniques available to monitor and control polymerization reactions and presenting some examples in each field.

[1]  Christian Fonteix,et al.  Development of New Concepts for the Control of Polymerization Processes: Multiobjective Optimization and Decision Engineering. II. Application of a Choquet Integral to an Emulsion Copolymerization Process , 2011 .

[2]  Mahdi Sharifzadeh,et al.  Integration of process design and control: A review , 2013 .

[3]  Kyoung‐Su Ha,et al.  Optimal reaction conditions for the minimization of energy consumption and by-product formation in a poly(ethylene terephthalate) process , 2002 .

[4]  W. Reed,et al.  Fundamental Measurements in Online Polymerization Reaction Monitoring and Control with a Focus on ACOMP , 2010 .

[5]  William L. Luyben,et al.  Use of dynamic simulation for reactor safety analysis , 2012, Comput. Chem. Eng..

[6]  Krzysztof Matyjaszewski,et al.  Controlled/"living" radical polymerization. atom transfer radical polymerization in the presence of transition-metal complexes , 1995 .

[7]  Zainal Ahmad,et al.  Modelling and control of different types of polymerization processes using neural networks technique: A review , 2010 .

[8]  Luiz Augusto da Cruz Meleiro,et al.  ANN-based soft-sensor for real-time process monitoring and control of an industrial polymerization process , 2009, Comput. Chem. Eng..

[9]  Klavs F. Jensen,et al.  On‐line molecular weight distribution estimation and control in batch polymerization , 1994 .

[10]  W. H. Ray,et al.  The dynamic behavior of continuous solution polymerization reactors. VII: Experimental study of a copolymerization reactor , 1995 .

[11]  J. Leiza,et al.  Control of microstructural properties in emulsion polymerization systems , 2002 .

[12]  Shengbin Jiang,et al.  Seeding as a means of controlling particle size in dispersion polymerization , 2008 .

[13]  P. Swapna Reddy,et al.  Comparative Study of Different Cascade Control Configurations for a Multiproduct Semibatch Polymerization Reactor , 2014 .

[14]  Enrique Luis Lima,et al.  Molecular weight distribution in composition controlled emulsion copolymerization , 2000 .

[15]  E. Lester,et al.  Continuous direct on-line reaction monitoring of a controlled polymerisationvia dielectric measurement , 2011 .

[16]  Anna Wolf,et al.  Polymerization Online Monitoring , 2010 .

[17]  C. Kiparissides,et al.  Comprehensive Dynamic Model for the Calculation of the Molecular Weight and Long Chain Branching Distributions in Metallocene-Catalyzed Ethylene Polymerization Reactors , 2000 .

[18]  Francis J. Doyle,et al.  Regulation of the Emulsion Particle Size Distribution to an Optimal Trajectory Using Partial Least Squares Model-Based Predictive Control , 2004 .

[19]  H. Schuler,et al.  Real-time estimation of the chain length distribution in a polymerization reactor—II. comparison of estimated and measured distribution functions , 1986 .

[20]  R. Arshady,et al.  Suspension, emulsion, and dispersion polymerization: A methodological survey , 1992 .

[21]  Mohd Azlan Hussain,et al.  Hybrid neural network—prior knowledge model in temperature control of a semi-batch polymerization process , 2004 .

[22]  Jong Min Lee,et al.  Progress and challenges in control of chemical processes. , 2014, Annual review of chemical and biomolecular engineering.

[23]  Alexander Penlidis,et al.  ON-LINE SENSORS FOR POLYMERIZATION REACTORS , 1990 .

[24]  Enrique Luis Lima,et al.  Control and design of average particle size in styrene suspension polymerizations using NIRS , 2000 .

[25]  Costas Kiparissides,et al.  Development of a General Mathematical Framework for Modeling Diffusion-Controlled Free-Radical Polymerization Reactions , 1992 .

[26]  Ying Wang,et al.  Feedback controllability assessment and control of particle size distribution in emulsion polymerisation , 2008 .

[27]  Victor M. Zavala,et al.  Dynamic optimization of a semi-batch reactor for polyurethane production , 2005 .

[28]  Yong Kuen Ho,et al.  Control of industrial gas phase propylene polymerization in fluidized bed reactors , 2012 .

[29]  Mohd Azlan Hussain,et al.  Control of polystyrene batch reactors using neural network based model predictive control (NNMPC): An experimental investigation , 2011 .

[30]  José M. Asua,et al.  CONTROL OF EMULSION POLYMERIZATION REACTORS USING A HIERARCHICAL FUZZY LOGIC/MODEL-BASED CONTROLLER , 2001 .

[31]  S. Engell,et al.  Simple Control Scheme for Batch Time Minimization of Exothermic Semibatch Polymerizations , 2013 .

[32]  M. Shahrokhi,et al.  Inferential closed-loop control of particle size distribution for styrene emulsion polymerization , 2008 .

[33]  C. D. Immanuel,et al.  Evolution of multimodal particle size distribution in vinyl acetate/butyl acrylate emulsion copolymerizations , 2003 .

[34]  Lorenz T. Biegler,et al.  Parameter Estimation for a Polymerization Reactor Model with a Composite-Step Trust-Region NLP Algorithm , 2004 .

[35]  Fernando V. Lima,et al.  Nonlinear stochastic modeling to improve state estimation in process monitoring and control , 2011 .

[36]  A. Hui,et al.  Thermal polymerization of styrene at high conversions and temperatures. An experimental study , 1972 .

[37]  Masoud Soroush.  State and parameter estimations and their applications in process control , 1998 .

[38]  Zhang Suzhen,et al.  Real-time estimation of the chain length distribution in a polymerization reactor , 1985 .

[39]  Ignacio E. Grossmann,et al.  Simultaneous design, scheduling, and optimal control of a methyl-methacrylate continuous polymerization reactor , 2008 .

[40]  José M. Asua,et al.  Emulsion polymerization: From fundamental mechanisms to process developments , 2004 .

[41]  D. Witenhafer,et al.  Increasing PVC suspension polymerization productivity by using temperature‐programmed reactions , 2000 .

[42]  Francis J. Doyle,et al.  Batch-to-batch control of characteristic points on the PSD in experimental emulsion polymerization , 2008 .

[43]  J. Farber,et al.  Steady state multiobjective optimization of continuous copolymerization reactors , 1986 .

[44]  Evaristo C. Biscaia,et al.  Optimization of batch solution polymerizations: Simulation studies using an inhibitor and a chain‐transfer agent , 1998 .

[45]  Michael F. Drenski,et al.  Simultaneous continuous, nonchromatographic monitoring and discrete chromatographic monitoring of polymerization reactions , 2009 .

[46]  J. Soares.  Polyolefins with Long Chain Branches Made with Single‐Site Coordination Catalysts: A Review of Mathematical Modeling Techniques for Polymer Microstructure , 2004 .

[47]  Z. Zeybek,et al.  Adaptive heuristic temperature control of a batch polymerisation reactor , 2004 .

[48]  Flávio Vasconcelos da Silva,et al.  Experimental investigations on fuzzy logic for process control , 2007 .

[49]  E. G. Chatzi,et al.  Recent Developments in Hardware Sensors For the On-Line Monitoring of Polymerization Reactions , 1999 .

[50]  A. Penlidis,et al.  Copolymer Composition Control Policies: Characteristics and Applications , 2008 .

[51]  J. Pinto,et al.  Control of Polymerization Reactors , 2008 .

[52]  Marianthi G. Ierapetritou,et al.  Integration of Scheduling and Control with Closed Loop Implementation , 2012 .

[53]  Hale Hapoglu,et al.  Self-tuning PID control of jacketed batch polystyrene reactor using genetic algorithm , 2008 .

[54]  Cláudio Augusto Oller do Nascimento,et al.  Neural network based approach for optimisation applied to an industrial nylon-6,6 polymerisation process , 1998 .

[55]  Wayne F. Reed,et al.  Absolute, On-Line Monitoring of Molar Mass during Polymerization Reactions , 1998 .

[56]  G. Polacco,et al.  Temperature profiles in batch methyl methacrylate polymerization in gelled suspension , 1996 .

[57]  David R. Liu,et al.  Sequence-Controlled Polymers , 2013, Science.

[58]  Jorge R. Vega,et al.  Continuous Emulsion Styrene-Butadiene Rubber (SBR) Process: Computer Simulation Study for Increasing Production and for Reducing Transients between Steady States , 2006 .

[59]  A. Brandolin,et al.  Simultaneous Design and Control of a Semibatch Styrene Polymerization Reactor , 2004 .

[60]  E. Biscaia,et al.  Nonlinear parameter estimation through particle swarm optimization , 2008 .

[61]  J. Leiza,et al.  Safety in Emulsion Polymerization Reactors: An Experimental Study , 2005 .

[62]  J. M. Asua,et al.  Estimation of conversion and copolymer composition in semicontinuous emulsion polymerization using calorimetric data , 1995 .

[63]  J. Pinto,et al.  Living free radical polymerization in tubular reactors. I. Modeling of the complete molecular weight distribution using probability generating functions , 2007 .

[64]  S. A. Sata,et al.  Temperature Control of a Bench‐Scale Batch Polymerization Reactor for Polystyrene Production , 2007 .

[65]  J. Leiza,et al.  On-line calorimetric control of emulsion polymerization reactors , 1996 .

[66]  Shiping Zhu,et al.  Control of gradient copolymer composition in ATRP using semibatch feeding policy , 2007 .

[67]  L. Biegler.  Nonlinear programming strategies for dynamic chemical process optimization , 2014, Theoretical Foundations of Chemical Engineering.

[68]  Deoki N. Saraf,et al.  On-line optimizing control of bulk polymerization of methyl methacrylate: Some experimental results for heater failure , 2002 .

[69]  Wayne F. Reed,et al.  Predictive control and verification of conversion kinetics and polymer molecular weight in semi-batch free radical homopolymer reactions , 2009 .

[70]  Jie Zhang,et al.  A reliable multi-objective control strategy for batch processes based on bootstrap aggregated neural network models , 2008 .

[71]  Feng Yang,et al.  Polymerization control and fast characterization of the stereo-defect distribution of heterogeneous Ziegler–Natta isotactic polypropylene , 2012 .

[72]  José M. Asua,et al.  Monomer addition policies for copolymer composition control in semicontinuous emulsion copolymerization , 1989 .

[73]  J. Asua,et al.  Knowledge-based choice of the initiator type for monomer removal by postpolymerization , 2002 .

[74]  Agustín Urretabizkaia,et al.  Maximizing production rate and scrub resistance of vinyl acetate–VeoVa 10 latexes , 2000 .

[75]  J. C. Cal,et al.  Competitive particle growth: A tool to control the particle size distribution for the synthesis of high solids content low viscosity latexes , 2011 .

[76]  A. B. Poore,et al.  On the dynamic behavior of continuous stirred tank reactors , 1974 .

[77]  Panagiotis D. Christofides,et al.  Control of particulate processes: Recent results and future challenges , 2007 .

[78]  Mehdi Rafizadeh,et al.  SEQUENTIAL LINEARIZATION ADAPTIVE CONTROL OF SOLUTION POLYMERIZATION OF METHYL METHACRYLATE IN A BATCH REACTOR , 2002 .

[79]  Fabiano A.N. Fernandes,et al.  Inverse modeling applications in emulsion polymerization of vinyl acetate , 2004 .

[80]  Rubens Maciel Filho,et al.  Fuzzy Model-Based Predictive Hybrid Control of Polymerization Processes , 2009 .

[81]  J. C. Cal,et al.  Control of particle size distribution for the synthesis of small particle size high solids content latexes , 2010 .

[82]  William R. Cluett,et al.  On‐line nonlinear model‐based estimation and control of a polymer reactor , 1997 .

[83]  Zhiqiang Ge,et al.  A comparative study of just-in-time-learning based methods for online soft sensor modeling , 2010 .

[84]  Rafiqul Gani,et al.  State‐of‐the‐art and progress in the optimization‐based simultaneous design and control for chemical processes , 2012 .

[85]  C. D. Immanuel,et al.  A Sensitivity Approach to Reachability Analysis for Particle Size Distribution in Semibatch Emulsion Polymerization , 2004 .

[86]  G. Xue,et al.  Controlling the Structure and Morphology of Monodisperse Polystyrene/Polyaniline Composite Particles , 2007 .

[87]  J. Pinto,et al.  Acrylic acid/vinyl acetate suspension copolymerizations. 2. Modeling and experimental results , 2004 .

[88]  H. Edwards,et al.  Process monitoring of polymer melts using in-line spectroscopy , 2007 .

[89]  D. Gilmore,et al.  Formulation and process modeling of biopolymer (polyhydroxyalkanoates: PHAs) production from industrial wastes by novel crossed experimental design , 2005 .

[90]  Wolfgang Marquardt,et al.  Optimal process operation for the production of linear polyethylene resins with tailored molecular weight distribution , 2011 .

[91]  Jinsong Zhao,et al.  An overview on controllability analysis of chemical processes , 2011 .

[92]  J. Asua,et al.  On-Line Copolymer Composition Control in the Semicontinuous Emulsion Copolymerization of Ethyl Acrylate and Methyl Methacrylate , 1993 .

[93]  S. Engell,et al.  Time optimal production of a specified particle size distribution in emulsion polymerization , 2007 .

[94]  M. González-Sierra,et al.  Semibatch Aqueous-Solution Polymerization of Acrylic Acid: Simultaneous Control of Molar Masses and Reaction Temperature , 2011 .

[95]  Grégory François,et al.  Dynamic Optimization of Batch Emulsion Polymerization Using MSIMPSA, a Simulated-Annealing-Based Algorithm , 2004 .

[96]  Mazen Alamir,et al.  Multivariable control of the polymer molecular weight in emulsion polymerization processes , 2011 .

[97]  J. Pinto,et al.  Analysis of Near Infrared Spectra during Methyl methacrylate (MMA) Suspension Polymerizations , 2011 .

[98]  Jean-François Lutz,et al.  Sequence control in polymer synthesis. , 2009, Chemical Society reviews.

[99]  W.-D. Hergeth,et al.  On-Line Characterization Methods , 1997 .

[100]  Daniel R. Lewin.  Modelling and control of an industrial PVC suspension polymerization reactor , 1996 .

[101]  Victor M. Zavala,et al.  Optimization-based strategies for the operation of low-density polyethylene tubular reactors: nonlinear model predictive control , 2009, Comput. Chem. Eng..

[102]  Christian Fonteix,et al.  Development of new concepts for the control of polymerization processes: Multiobjective optimization and decision engineering. I. Application to emulsion homopolymerization of styrene , 2003 .

[103]  G. P. Rangaiah,et al.  Multi-objective optimization of the operation of an industrial low-density polyethylene tubular reactor using genetic algorithm and its jumping gene adaptations , 2006 .

[104]  Fernando Aller,et al.  Modelling, simulation and control of an industrial, semi-batch, emulsion-polymerization reactor , 2011, Comput. Chem. Eng..

[105]  E. Lima,et al.  Monitoring and control of styrene solution polymerization using NIR spectroscopy , 2003 .

[106]  Zhihong Yuan,et al.  Phase behavior analysis for industrial polymerization reactors , 2011 .

[107]  M. Soroush.  Nonlinear state-observer design with application to reactors , 1997 .

[108]  Jose A. Romagnoli,et al.  Inferential conversion monitoring and control in emulsion polymerisation through calorimetric measurements , 2002 .

[109]  Ramdhane Dhib,et al.  Unscented Kalman filter based nonlinear model predictive control of a LDPE autoclave reactor , 2011 .

[110]  B. Bequette,et al.  Product property and production rate control of styrene polymerization , 2002 .

[111]  E. Lima,et al.  Closed-Loop Composition and Molecular Weight Control of a Copolymer Latex Using Near-Infrared Spectroscopy , 2002 .

[112]  E. Lima,et al.  Dynamic optimization of semicontinuous emulsion copolymerization reactions: composition and molecular weight distribution , 2001 .

[113]  Enrique Luis Lima,et al.  Detection of monomer droplets in a polymer latex by near-infrared spectroscopy , 2001 .

[114]  Diego Martinez Prata,et al.  In-Line Monitoring of Bulk Polypropylene Reactors Based on Data Reconciliation Procedures , 2008 .

[115]  Panagiotis D. Christofides,et al.  Fault-tolerant control of a polyethylene reactor , 2007 .

[116]  Marcelo Embiruçu,et al.  Fuzzy control of a nylon polymerization semi-batch reactor , 2009, Fuzzy Sets Syst..

[117]  E. Lima,et al.  Dynamic optimization of non-linear emulsion copolymerization systems: Open-loop control of composition and molecular weight distribution , 2002 .

[118]  Ravindra D. Gudi,et al.  Optimal Grade Transition in Polymerization Reactors: A Comparative Case Study† , 2006 .

[119]  J. Asua,et al.  Postpolymerization of vinyl acetate‐containing latexes , 2002 .

[120]  M. Morbidelli,et al.  Densimetry for on‐line conversion monitoring in emulsion homo‐ and copolymerization , 1993 .

[121]  Wolfgang Marquardt,et al.  A two-layer architecture for economically optimal process control and operation , 2011 .

[122]  Argimiro Resende Secchi,et al.  Constrained optimal batch polymerization reactor control , 1990 .

[123]  Lorenz T. Biegler,et al.  Integrated control and process design during optimal polymer grade transition operations , 2008, Comput. Chem. Eng..

[124]  R. Hass,et al.  Photon density wave spectroscopy for dilution-free sizing of highly concentrated nanoparticles during starved-feed polymerization. , 2011, Chemphyschem : a European journal of chemical physics and physical chemistry.

[125]  Marcelo Embiruçu,et al.  Modeling of end-use properties of poly(propylene/ethylene) resins , 2001 .

[126]  G. Maschio,et al.  Reaction Inhibition as a Method for Preventing Thermal Runaway in Industrial Processes , 2007 .

[127]  Jie Zhang,et al.  A Reliable Neural Network Model Based Optimal Control Strategy for a Batch Polymerization Reactor , 2004 .

[128]  E. Lima,et al.  Data Reconciliation and Control in Styrene-Butadiene Emulsion Polymerizations , 2011 .

[129]  Liulin Cao,et al.  Control and modeling of temperature distribution in a tubular polymerization process , 2007, Comput. Chem. Eng..

[130]  Brian Roffel,et al.  Non-linear model based control of a propylene polymerization reactor , 2007 .

[131]  Sachin C. Patwardhan,et al.  Data-Driven Model Based Control of a Multi-Product Semi-Batch Polymerization Reactor , 2007 .

[132]  Vincent G. Gomes,et al.  Optimal operating strategies for emulsion terpolymerisation , 2008 .

[133]  Yuan Tian,et al.  Dynamic On‐Line Reoptimization Control of a Batch MMA Polymerization Reactor Using Hybrid Neural Network Models , 2004 .

[134]  D. Manca,et al.  Dynamic Modeling of a Poly(ethylene terephthalate) Solid-State Polymerization Reactor II: Model Predictive Control , 2004 .

[135]  Jie Zhang,et al.  Multiple neural networks modeling techniques in process control: a review , 2009 .

[136]  T. McKenna,et al.  Online monitoring of the evolution of the number of particles in emulsion polymerization by conductivity measurements. I. Model formulation , 2003 .

[137]  Christos Georgakis,et al.  Online Estimation of Reaction Rates in Semicontinuous Reactors , 1995 .

[138]  Flavio Manenti,et al.  Considerations on nonlinear model predictive control techniques , 2011, Comput. Chem. Eng..

[139]  Martin Schlegel,et al.  Optimization and Control of Polymerization Processes , 2005 .

[140]  A. Lohi,et al.  Optimal control determination of MMA polymerization in non-isothermal batch reactor using bifunctional initiator , 2005 .

[141]  Iiro Harjunkoski,et al.  Integration of scheduling and control - Theory or practice? , 2009, Comput. Chem. Eng..

[142]  Jie Zhang,et al.  Integrated tracking control strategy for batch processes using a batch-wise linear time-varying perturbation model , 2007 .

[143]  Nida Sheibat-Othman,et al.  Monitoring and Control of Free-Radical Polymerizations Using Near-Infrared Spectroscopy , 2004 .

[144]  E. F. Costa,et al.  On the numerical solution and optimization of styrene polymerization in tubular reactors , 2003, Comput. Chem. Eng..

[145]  W. Hergeth,et al.  Industrial polymerization monitoring. , 2011, Analytical and bioanalytical chemistry.

[146]  Alina M. Alb,et al.  Automatic, continuous online monitoring of polymerization reactions (ACOMP): Progress in characterization of polymers and polymerization reactions , 2008 .

[147]  Klaus Tauer,et al.  On-line surface tension measurements inside stirred reactors , 1999 .

[148]  Yuesheng Ye,et al.  Modeling and Control of Sequence Length Distribution for Controlled Radical (RAFT) Copolymerization , 2009 .

[149]  Evaristo C. Biscaia,et al.  Multi‐objective dynamic optimization of semi‐batch polymerization processes , 2004 .

[150]  J. Leiza,et al.  Simultaneous control of copolymer composition and MWD in emulsion copolymerization , 2001 .

[151]  M. Parvazinia,et al.  Dynamic simulation and control of auto-refrigerated CSTR and tubular reactor for bulk styrene polymerization , 2012 .

[152]  K. Alhumaizi,et al.  Control of molecular weight distribution of polyethylene in gas-phase fluidized bed reactors , 2010 .

[153]  E. L. Lima,et al.  Control strategies for complex chemical processes. Applications in polymerization processes , 2003, Comput. Chem. Eng..

[154]  J. Pinto,et al.  Suspension Polymerization Processes , 2013 .

[155]  J. Alexander,et al.  Dynamics of a continuous stirred tank reactor for styrene polymerization initiated by a binary initiator mixture. II: Effect of viscosity dependent heat transfer coefficient , 1992 .

[156]  P. H. Araújo,et al.  Spectroscopic on-line monitoring of reactions in dispersed medium: chemometric challenges. , 2007, Analytica chimica acta.

[157]  Andrew Klein,et al.  An experimental study of adaptive Kalman filtering in emulsion copolymerization , 1991 .

[158]  J. Leiza,et al.  Molecular‐weight distribution control in emulsion polymerization , 1998 .

[159]  Claudio Scali,et al.  Parameter estimation in Extended Kalman Filters for quality control in polymerization reactors , 1996 .

[160]  J. Gauthier,et al.  A simple observer for nonlinear systems applications to bioreactors , 1992 .

[161]  Babatunde A. Ogunnaike,et al.  Integrating systems design and control using dynamic flexibility analysis , 2007 .

[162]  A. Lohi,et al.  Optimal Control of Batch MMA Polymerization with Specified Time, Monomer Conversion, and Average Polymer Molecular Weights , 2005 .

[163]  Nuno M.C. Oliveira,et al.  Optimization and nonlinear Model Predictive Control of batch polymerization systems , 2002 .

[164]  Mohd Azlan Hussain,et al.  Dynamics and Predictive Control of Gas Phase Propylene Polymerization in Fluidized Bed Reactors , 2013 .

[165]  Ricardo A. F. Machado,et al.  Online Monitoring of Suspension Polymerization Reactions Using Raman Spectroscopy , 2004 .

[166]  W. H. Ray,et al.  The dynamic behavior of continuous solution polymerization reactors—IV. Dynamic stability and bifurcation analysis of an experimental reactor , 1989 .

[167]  Kishalay Mitra,et al.  Multicriteria Optimal Control of Polypropylene Terepthalate Polymerization Reactor , 2007 .

[168]  Zainal Ahmad,et al.  MODEL PREDICTIVE CONTROL (MPC) AND ITS CURRENT ISSUES IN CHEMICAL ENGINEERING , 2012 .

[169]  José M. Asua,et al.  Control of Molecular Weight Distribution in Emulsion Polymerization Using On-Line Reaction Calorimetry , 2001 .

[170]  Zoltan K. Nagy,et al.  Model predictive control of a PVC batch reactor , 1997 .

[171]  F. Schork,et al.  On‐line measurement of surface tension and density with applications to emulsion polymerization , 1983 .

[172]  Jorge C. Ramirez,et al.  Kinetics of the styrene emulsion polymerization above cmc. II. Agitation effect on molecular weight , 2005 .

[173]  Sebastian Engell,et al.  Realization of online optimizing control in an industrial semi-batch polymerization , 2014 .

[174]  S. Gupta,et al.  Multi‐Objective Optimization of Semi‐Batch Copolymerization Reactors Using Adaptations of Genetic Algorithm , 2004 .

[175]  C. D. Immanuel,et al.  Nonisothermal Modeling and Sensitivity Studies for Batch and Semibatch Emulsion Polymerization of Styrene , 2003 .

[176]  S. Schlüter,et al.  Control of runaway polymerization reactions by injection of inhibiting agents — A contribution to the safety of chemical reactors , 1996 .

[177]  Alexandre F. Santos,et al.  Monitoring and Control of Polymerization Reactors Using NIR Spectroscopy , 2005 .

[178]  W. H. Ray,et al.  The dynamic behavior of continuous solution polymerization reactors—IX. Effects of inhibition , 1996 .

[179]  José M. Asua,et al.  Copolymer composition control of emulsion copolymers in reactors with limited capacity for heat removal , 1991 .

[180]  J. Romagnoli,et al.  On-line multi-variable predictive control of molar mass and particle size distributions in free-radical emulsion copolymerization , 2005 .

[181]  O. Bilous,et al.  Chemical reactor stability and sensitivity , 1955 .

[182]  Ana Maria Frattini Fileti,et al.  Fuzzy control of a PMMA batch reactor: Development and experimental testing , 2005, Comput. Chem. Eng..

[183]  W. H. Ray,et al.  Reactor residence time distribution effects on the multistage polymerization of olefins—I. Basic principles and illustrative examples, polypropylene , 1996 .

[184]  Marcelo Embiruçu,et al.  Modeling and predictive control using fuzzy logic: Application for a polymerization system , 2010 .

[185]  Mariano Asteasuain,et al.  Integration of control aspects and uncertainty in the process design of polymerization reactors , 2007 .

[186]  J. Chiefari,et al.  Living free-radical polymerization by reversible addition - Fragmentation chain transfer: The RAFT process , 1998 .

[187]  Zoltan K. Nagy,et al.  Evaluation study of an efficient output feedback nonlinear model predictive control for temperature tracking in an industrial batch reactor , 2007 .

[188]  Frank Allgöwer,et al.  Optimization strategies for a MMA polymerization reactor , 2007, Comput. Chem. Eng..

[189]  Sebastian Engell,et al.  Optimal operation: Scheduling, advanced control and their integration , 2012, Comput. Chem. Eng..

[190]  J. Pinto,et al.  Modeling and optimization of suspension SAN polymerization re actors , 1997 .

[191]  R. Gesthuisen,et al.  Determining the best reaction calorimetry technique: theoretical development , 2005, Comput. Chem. Eng..

[192]  Enrique Luis Lima,et al.  In-line evaluation of average particle size in styrene suspension polymerizations using near-infrared spectroscopy , 1998 .

[193]  Jie Zhang,et al.  Batch-to-batch optimal control of a batch polymerisation process based on stacked neural network models , 2008 .