DawnRank: discovering personalized driver genes in cancer
暂无分享,去创建一个
[1] Sergey Brin,et al. The Anatomy of a Large-Scale Hypertextual Web Search Engine , 1998, Comput. Networks.
[2] Rajeev Motwani,et al. The PageRank Citation Ranking : Bringing Order to the Web , 1999, WWW 1999.
[3] L. Serrano,et al. Engineering stability in gene networks by autoregulation , 2000, Nature.
[4] Minoru Kanehisa,et al. The KEGG database. , 2002, Novartis Foundation symposium.
[5] W. Kolch,et al. The role of MAPK pathways in the action of chemotherapeutic drugs. , 2002, Carcinogenesis.
[6] Hao Wu,et al. Distinct molecular mechanism for initiating TRAF6 signalling , 2002, Nature.
[7] K. Honda,et al. Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence. , 2003, Nature.
[8] T. Hubbard,et al. A census of human cancer genes , 2004, Nature Reviews Cancer.
[9] A. Prescott,et al. Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates , 2004, The EMBO journal.
[10] G. Dranoff,et al. Cytokines in cancer pathogenesis and cancer therapy , 2004, Nature Reviews Cancer.
[11] Desmond J. Higham,et al. GeneRank: Using search engine technology for the analysis of microarray experiments , 2005, BMC Bioinformatics.
[12] Wen-Lin Kuo,et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. , 2006, Cancer cell.
[13] E. Birney,et al. Patterns of somatic mutation in human cancer genomes , 2007, Nature.
[14] K. Wood,et al. Centromere-Associated Protein E: A Motor That Puts the Brakes on the Mitotic Checkpoint , 2008, Clinical Cancer Research.
[15] Joshua M. Korn,et al. Comprehensive genomic characterization defines human glioblastoma genes and core pathways , 2008, Nature.
[16] Susmita Datta,et al. Finding common genes in multiple cancer types through meta-analysis of microarray experiments: a rank aggregation approach. , 2008, Genomics.
[17] E. Birney,et al. Patterns of somatic mutation in human cancer genomes , 2007, Nature.
[18] F. He,et al. JAB1 accelerates mitochondrial apoptosis by interaction with proapoptotic BclGs. , 2008, Cellular signalling.
[19] Azadeh Shakery,et al. DirichletRank: Solving the zero-one gap problem of PageRank , 2008, TOIS.
[20] Samuel Leung,et al. Basal-Like Breast Cancer Defined by Five Biomarkers Has Superior Prognostic Value than Triple-Negative Phenotype , 2008, Clinical Cancer Research.
[21] G. Parmigiani,et al. Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses , 2008, Science.
[22] Brian H. Dunford-Shore,et al. Somatic mutations affect key pathways in lung adenocarcinoma , 2008, Nature.
[23] R. Leduc,et al. Lysosomotropic drugs inhibit maturation of transforming growth factor-beta. , 2008, Canadian journal of physiology and pharmacology.
[24] R. McLendon,et al. Glioblastoma proto-oncogene SEC61gamma is required for tumor cell survival and response to endoplasmic reticulum stress. , 2009, Cancer research.
[25] Pooja Mittal,et al. A novel signaling pathway impact analysis , 2009, Bioinform..
[26] J. Komorowski,et al. Characterization of novel and complex genomic aberrations in glioblastoma using a 32K BAC array. , 2009, Neuro-oncology.
[27] Leyla Isik,et al. Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations. , 2009, Cancer research.
[28] Kenneth H. Buetow,et al. PID: the Pathway Interaction Database , 2008, Nucleic Acids Res..
[29] J. Uhm. Comprehensive genomic characterization defines human glioblastoma genes and core pathways , 2009 .
[30] Eugene A. Mash,et al. Molecular Pharmacology and Antitumor Activity of PHT-427, a Novel Akt/Phosphatidylinositide-Dependent Protein Kinase 1 Pleckstrin Homology Domain Inhibitor , 2010, Molecular Cancer Therapeutics.
[31] K. Kinzler,et al. Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation , 2010, Proceedings of the National Academy of Sciences.
[32] S. Gabriel,et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. , 2010, Cancer cell.
[33] E. Mardis,et al. Analysis of next-generation genomic data in cancer: accomplishments and challenges. , 2010, Human molecular genetics.
[34] Eli Upfal,et al. Algorithms for Detecting Significantly Mutated Pathways in Cancer , 2010, RECOMB.
[35] S. Steinberg,et al. Nuclear factor κB transcription factors are coexpressed and convey a poor outcome in ovarian cancer , 2010, Cancer.
[36] L. Stein,et al. A human functional protein interaction network and its application to cancer data analysis , 2010, Genome Biology.
[37] D. Pe’er,et al. An Integrated Approach to Uncover Drivers of Cancer , 2010, Cell.
[38] R. Hruban,et al. Prioritization of driver mutations in pancreatic cancer using cancer-specific high-throughput annotation of somatic mutations (CHASM) , 2010, Cancer biology & therapy.
[40] Yuan Qi,et al. Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA , IDH 1 , EGFR , and NF 1 Citation Verhaak , 2010 .
[41] Signalling: The calcium connection , 2010, Nature Reviews Cancer.
[42] C. Sander,et al. Predicting the functional impact of protein mutations: application to cancer genomics , 2011, Nucleic acids research.
[43] Benjamin J. Raphael,et al. Integrated Genomic Analyses of Ovarian Carcinoma , 2011, Nature.
[44] Yang Liu,et al. Targeting HIF1α eliminates cancer stem cells in hematological malignancies. , 2011, Cell stem cell.
[45] S. Davis,et al. Exome sequencing identifies GRIN2A as frequently mutated in melanoma , 2011, Nature Genetics.
[46] M. Guyer,et al. Charting a course for genomic medicine from base pairs to bedside , 2011, Nature.
[47] Eli Upfal,et al. De Novo Discovery of Mutated Driver Pathways in Cancer , 2011, RECOMB.
[48] Eli Upfal,et al. Algorithms for Detecting Significantly Mutated Pathways in Cancer , 2010, RECOMB.
[49] D. Pe’er,et al. Principles and Strategies for Developing Network Models in Cancer , 2011, Cell.
[50] Renato V Iozzo,et al. Proteoglycans in cancer biology, tumour microenvironment and angiogenesis , 2011, Journal of cellular and molecular medicine.
[51] Ying Zheng,et al. Therapeutic Potential of AZD1480 for the Treatment of Human Glioblastoma , 2011, Molecular Cancer Therapeutics.
[52] K. Tachibana,et al. FoxO3a Functions as a Key Integrator of Cellular Signals That Control Glioblastoma Stem‐like Cell Differentiation and Tumorigenicity , 2011, Stem cells.
[53] Lincoln Stein,et al. Reactome: a database of reactions, pathways and biological processes , 2010, Nucleic Acids Res..
[54] Michael Schroeder,et al. Google Goes Cancer: Improving Outcome Prediction for Cancer Patients by Network-Based Ranking of Marker Genes , 2012, PLoS Comput. Biol..
[55] A. Gonzalez-Perez,et al. Functional impact bias reveals cancer drivers , 2012, Nucleic acids research.
[56] Madhu Chetty,et al. Issues impacting genetic network reverse engineering algorithm validation using small networks. , 2012, Biochimica et biophysica acta.
[57] Scott M Lippman,et al. Targeting the MAPK–RAS–RAF signaling pathway in cancer therapy , 2012, Expert opinion on therapeutic targets.
[58] C. Sander,et al. Mutual exclusivity analysis identifies oncogenic network modules. , 2012, Genome research.
[59] H. Ford,et al. Molecular Pathways Molecular Pathways : Targeting the TGF-b Pathway for Cancer Therapy , 2012 .
[60] Benjamin J. Raphael,et al. De novo discovery of mutated driver pathways in cancer , 2011 .
[61] F. Bertucci,et al. A refined molecular taxonomy of breast cancer , 2011, Oncogene.
[62] K. Watabe,et al. WNT7A Regulates Tumor Growth and Progression in Ovarian Cancer through the WNT/β-Catenin Pathway , 2012, Molecular Cancer Research.
[63] Matthew B. Callaway,et al. MuSiC: Identifying mutational significance in cancer genomes , 2012, Genome research.
[64] David Haussler,et al. PARADIGM-SHIFT predicts the function of mutations in multiple cancers using pathway impact analysis , 2012, Bioinform..
[65] Susumu Goto,et al. KEGG for integration and interpretation of large-scale molecular data sets , 2011, Nucleic Acids Res..
[66] Matteo D'Antonio,et al. Integrated analysis of recurrent properties of cancer genes to identify novel drivers , 2012, Genome Biology.
[67] Peng Zhang,et al. Tumor-Associated Microglia/Macrophages Enhance the Invasion of Glioma Stem-like Cells via TGF-β1 Signaling Pathway , 2012, The Journal of Immunology.
[68] Nicholas T. Ingolia,et al. The translational landscape of mTOR signalling steers cancer initiation and metastasis , 2012, Nature.
[69] A. Bashashati,et al. DriverNet: uncovering the impact of somatic driver mutations on transcriptional networks in cancer , 2012, Genome Biology.
[70] Todd R. Golub,et al. PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling , 2011, Oncogene.
[71] A. Sivachenko,et al. Sequence analysis of mutations and translocations across breast cancer subtypes , 2012, Nature.
[72] Steven J. M. Jones,et al. Comprehensive molecular portraits of human breast tumors , 2012, Nature.
[73] M. Stratton. Journeys into the genome of cancer cells , 2013, EMBO molecular medicine.
[74] Gabor T. Marth,et al. Integrative Annotation of Variants from 1092 Humans: Application to Cancer Genomics , 2013, Science.
[75] Sridhar Ramaswamy,et al. Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis , 2013, Proceedings of the National Academy of Sciences.
[76] Xuegong Zhang,et al. Identifying potential cancer driver genes by genomic data integration , 2013, Scientific Reports.
[77] Kevin C. Chu,et al. Amplification of FRS2 and activation of FGFR/FRS2 signaling pathway in high-grade liposarcoma. , 2013, Cancer research.
[78] K. Kinzler,et al. Cancer Genome Landscapes , 2013, Science.
[79] David Haussler,et al. Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE) , 2013, Bioinform..
[80] Steven J. M. Jones,et al. Comprehensive molecular portraits of human breast tumours , 2013 .
[81] Hannah Carter,et al. CRAVAT: cancer-related analysis of variants toolkit , 2013, Bioinform..
[82] Li Fan,et al. TRAF6 upregulates expression of HIF-1α and promotes tumor angiogenesis. , 2013, Cancer research.
[83] Ophir D Klein,et al. Lgr5-expressing cells are sufficient and necessary for postnatal mammary gland organogenesis. , 2013, Cell reports.
[84] Gary D Bader,et al. Comprehensive identification of mutational cancer driver genes across 12 tumor types , 2013, Scientific Reports.
[85] Gary D Bader,et al. Systematic analysis of somatic mutations in phosphorylation signaling predicts novel cancer drivers , 2013 .
[86] Jian Ma,et al. A network-assisted co-clustering algorithm to discover cancer subtypes based on gene expression , 2014, BMC Bioinformatics.
[87] Peilin Jia,et al. VarWalker: Personalized Mutation Network Analysis of Putative Cancer Genes from Next-Generation Sequencing Data , 2014, PLoS Comput. Biol..
[88] Dima Suki,et al. Extent of resection of glioblastoma revisited: personalized survival modeling facilitates more accurate survival prediction and supports a maximum-safe-resection approach to surgery. , 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[89] S. Gabriel,et al. Discovery and saturation analysis of cancer genes across 21 tumor types , 2014, Nature.
[90] Susumu Goto,et al. Data, information, knowledge and principle: back to metabolism in KEGG , 2013, Nucleic Acids Res..