MDM2 Inhibits PCAF (p300/CREB-binding Protein-associated Factor)-mediated p53 Acetylation*
暂无分享,去创建一个
M. Dai | Hua Lu | Xiang-Jiao Yang | Xiang-Jiao Yang | Hua Lu | Yetao Jin | Shelya X Zeng | Mu-Shui Dai | Shelya X. Zeng | Yetao Jin | Yetao Jin
[1] W. Kaelin,et al. MDM2 Suppresses p73 Function without Promoting p73 Degradation , 1999, Molecular and Cellular Biology.
[2] D. Livingston,et al. Binding and modulation of p53 by p300/CBP coactivators , 1997, Nature.
[3] B. Howard,et al. A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A , 1996, Nature.
[4] Wei Gu,et al. Synergistic activation of transcription by CBP and p53 , 1997, Nature.
[5] J. Pietenpol,et al. Kinetics of p53 Binding to Promoter Sites In Vivo , 2001, Molecular and Cellular Biology.
[6] K. Gardner,et al. Recruitment of p300/CBP in p53-Dependent Signal Pathways , 1997, Cell.
[7] D. Livingston,et al. p300/MDM2 complexes participate in MDM2-mediated p53 degradation. , 1998, Molecular cell.
[8] R. Weinberg,et al. hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase , 2001, Cell.
[9] Myles Brown,et al. Cofactor Dynamics and Sufficiency in Estrogen Receptor–Regulated Transcription , 2000, Cell.
[10] V. Adler,et al. Mdm2 association with p53 targets its ubiquitination , 1998, Oncogene.
[11] M. E. Perry,et al. The p53 Tumor Suppressor Protein Does Not Regulate Expression of Its Own Inhibitor, MDM2, Except under Conditions of Stress , 2000, Molecular and Cellular Biology.
[12] A. Giaccia,et al. The complexity of p53 modulation: emerging patterns from divergent signals. , 1998, Genes & development.
[13] M. Oren,et al. Wild type p53 can mediate sequence-specific transactivation of an internal promoter within the mdm2 gene. , 1993, Oncogene.
[14] R. Copeland,et al. Human mdm2 Mediates Multiple Mono-ubiquitination of p53 by a Mechanism Requiring Enzyme Isomerization* , 2001, The Journal of Biological Chemistry.
[15] A. Levine,et al. Mapping of the p53 and mdm-2 interaction domains. , 1993, Molecular and cellular biology.
[16] Functional activation of p53 via phosphorylation following DNA damage by UV but not γ radiation , 1998 .
[17] W. Kaelin,et al. Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex. , 2001, Genes & development.
[18] Stephen N. Jones,et al. Regulation of p53 stability by Mdm2 , 1997, Nature.
[19] Wen‐Ming Yang,et al. Histone Deacetylases Specifically Down-regulate p53-dependent Gene Activation* , 2000, The Journal of Biological Chemistry.
[20] Delin Chen,et al. Deacetylation of p53 modulates its effect on cell growth and apoptosis , 2000, Nature.
[21] T. Billiar,et al. Inhibition of Protein Synthesis by Nitric Oxide Correlates with Cytostatic Activity: Nitric Oxide Induces Phosphorylation of Initiation Factor eIF-2α , 1998, Molecular medicine.
[22] Y Taya,et al. DNA damage induces phosphorylation of the amino terminus of p53. , 1997, Genes & development.
[23] Hirofumi Tanaka,et al. Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53 , 1997, FEBS letters.
[24] A. Levine. p53, the Cellular Gatekeeper for Growth and Division , 1997, Cell.
[25] A. Carr,et al. Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[26] Shengyun Fang,et al. Mdm2 Is a RING Finger-dependent Ubiquitin Protein Ligase for Itself and p53* , 2000, The Journal of Biological Chemistry.
[27] A. Levine,et al. The regulation of p53-mediated transcription and the roles of hTAFII31 and mdm-2. , 1994, Harvey lectures.
[28] A. Levine,et al. The p53-mdm-2 autoregulatory feedback loop. , 1993, Genes & development.
[29] Daiqing Liao,et al. Adenovirus E1B 55-Kilodalton Oncoprotein Inhibits p53 Acetylation by PCAF , 2000, Molecular and Cellular Biology.
[30] A. Levine,et al. Human TAFII31 protein is a transcriptional coactivator of the p53 protein. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[31] Delin Chen,et al. Negative Control of p53 by Sir2α Promotes Cell Survival under Stress , 2001, Cell.
[32] H. Samuels,et al. pEXPRESS: a family of expression vectors containing a single transcription unit active in prokaryotes, eukaryotes and in vitro. , 1991, Gene.
[33] J. Trent,et al. WAF1, a potential mediator of p53 tumor suppression , 1993, Cell.
[34] Wei Gu,et al. Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain , 1997, Cell.
[35] A. Levine,et al. Ultraviolet radiation, but not gamma radiation or etoposide-induced DNA damage, results in the phosphorylation of the murine p53 protein at serine-389. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[36] A. Levine,et al. The high levels of p53 present in adenovirus early region 1-transformed human cells do not cause up-regulation of MDM2 expression. , 1995, Virology.
[37] A. Levine,et al. Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein. , 1994, Genes & development.
[38] Zhi-Min Yuan,et al. Role for p300 in Stabilization of p53 in the Response to DNA Damage* , 1999, The Journal of Biological Chemistry.
[39] T. Unger,et al. Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2 , 1999, The EMBO journal.
[40] D. Keller,et al. MDM2 inhibits p300-mediated p53 acetylation and activation by forming a ternary complex with the two proteins. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[41] T. Halazonetis,et al. Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53. , 2000, Genes & development.
[42] J. Roth,et al. Multiple Lysine Mutations in the C-Terminal Domain of p53 Interfere with MDM2-Dependent Protein Degradation and Ubiquitination , 2000, Molecular and Cellular Biology.
[43] S. Berger,et al. p53 Sites Acetylated In Vitro by PCAF and p300 Are Acetylated In Vivo in Response to DNA Damage , 1999, Molecular and Cellular Biology.
[44] C. Prives,et al. p53: puzzle and paradigm. , 1996, Genes & development.
[45] Ettore Appella,et al. p300/CBP‐mediated p53 acetylation is commonly induced by p53‐activating agents and inhibited by MDM2 , 2001, The EMBO journal.
[46] M. Kulesz-Martin,et al. Functional quantification of DNA-binding proteins p53 and estrogen receptor in cells and tumor tissues by DNA affinity immunoblotting. , 2001, Cancer research.
[47] S. Elledge,et al. DNA damage-induced activation of p53 by the checkpoint kinase Chk2. , 2000, Science.
[48] M. Oren,et al. Mdm2 promotes the rapid degradation of p53 , 1997, Nature.
[49] R. Evans,et al. A Viral Mechanism for Inhibition of p300 and PCAF Acetyltransferase Activity , 1999, Cell.
[50] R. Tjian,et al. Repression of p53-mediated transcription by MDM2: a dual mechanism. , 1997, Genes & development.
[51] K. Sakaguchi,et al. DNA damage activates p53 through a phosphorylation-acetylation cascade. , 1998, Genes & development.
[52] Y Taya,et al. The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. , 2000, Genes & development.
[53] Hua Lu,et al. The N-Terminal Domain of p73 Interacts with the CH1 Domain of p300/CREB Binding Protein and Mediates Transcriptional Activation and Apoptosis , 2000, Molecular and Cellular Biology.