Age-Specific Prevalence of Visual Impairment and Refractive Error in Children Aged 3-10 Years in Shanghai, China.

Purpose We assessed changes in age-specific prevalence of refractive error at the time of starting school, by comparing preschool and school age cohorts in Shanghai, China. Methods A cross-sectional study was done in Jiading District, Shanghai during November and December 2013. We randomly selected 7 kindergartens and 7 primary schools, with probability proportionate to size. Chinese children (n = 8398) aged 3 to 10 years were enumerated, and 8267 (98.4%) were included. Children underwent distance visual acuity assessment and refraction measurement by cycloplegic autorefraction and subjective refraction. Results The prevalence of uncorrected visual acuity (UCVA), presenting visual acuity, and best-corrected visual acuity in the better eye of ≤20/40 was 19.8%, 15.5%, and 1.7%, respectively. Among those with UCVA ≤ 20/40, 93.2% could achieve visual acuity of ≥20/32 with refraction. Only 28.7% (n = 465) of children with UCVA in the better eye of ≤20/40 wore glasses. Prevalence of myopia (spherical equivalent ≤-0.5 diopters [D] in at least one eye) increased from 1.78% in 3-year-olds to 52.2% in 10-year-olds, while prevalence of hyperopia (spherical equivalent ≥+2.0 D) decreased from 17.8% among 3-year-olds to 2.6% by 10 years of age. After adjusting for age, attending elite "high-level" school was statistically associated with greater myopia prevalence. Conclusions The prevalence of myopia was lower or comparable to that reported in other populations from age 3 to 5 years, but increased dramatically after 6 years, consistent with a strong environmental role of schooling on myopia development.

[1]  Hu Liu,et al.  Prevalence and causes of reduced visual acuity among children aged three to six years in a metropolis in China , 2016, Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians.

[2]  P. Mitchell,et al.  Assessing the Genetic Predisposition of Education on Myopia: A Mendelian Randomization Study , 2016, Genetic epidemiology.

[3]  N. Congdon,et al.  Population Prevalence of Need for Spectacles and Spectacle Ownership Among Urban Migrant Children in Eastern China. , 2015, JAMA ophthalmology.

[4]  J. Mesman,et al.  Child Development in the Face of Rural-to-Urban Migration in China , 2015, Perspectives on psychological science : a journal of the Association for Psychological Science.

[5]  N. Congdon,et al.  Safety of Spectacles for Children's Vision: A Cluster-Randomized Controlled Trial. , 2015, American journal of ophthalmology.

[6]  Gabriëlle H S Buitendijk,et al.  Increasing Prevalence of Myopia in Europe and the Impact of Education , 2015, Ophthalmology.

[7]  N. Congdon,et al.  Factors Underlying Different Myopia Prevalence between Middle- and Low-income Provinces in China. , 2015, Ophthalmology.

[8]  M. He,et al.  Normative distribution of visual acuity in 3- to 6-year-old Chinese preschoolers: the Shenzhen kindergarten eye study. , 2015, Investigative ophthalmology & visual science.

[9]  S. Sheu,et al.  Risk Factors For and Progression of Myopia in Young Taiwanese Men , 2015, Ophthalmic epidemiology.

[10]  Qin-Mei Wang,et al.  Refractive error among urban preschool children in Xuzhou, China. , 2014, International journal of clinical and experimental pathology.

[11]  M. Beutel,et al.  Myopia and level of education: results from the Gutenberg Health Study. , 2014, Ophthalmology.

[12]  J. Jonas,et al.  Prevalence of myopia in school children in greater Beijing: the Beijing Childhood Eye Study , 2014, Acta ophthalmologica.

[13]  Y. Teo,et al.  Education influences the association between genetic variants and refractive error: a meta-analysis of five Singapore studies. , 2014, Human molecular genetics.

[14]  J. Jonas,et al.  Refractive Error, Visual Acuity and Causes of Vision Loss in Children in Shandong, China. The Shandong Children Eye Study , 2013, PloS one.

[15]  Gretchen A. Stevens,et al.  Causes of vision loss worldwide, 1990-2010: a systematic analysis. , 2013, The Lancet. Global health.

[16]  X. Qu,et al.  Myopia Screening: Combining Visual Acuity and Noncycloplegic Autorefraction , 2013, Optometry and vision science : official publication of the American Academy of Optometry.

[17]  P. Mitchell,et al.  Design, Methodology and Baseline Data of a School-based Cohort Study in Central China: The Anyang Childhood Eye Study , 2013, Ophthalmic epidemiology.

[18]  Weizhong Lan,et al.  Refractive Errors in 3–6 Year-Old Chinese Children: A Very Low Prevalence of Myopia? , 2013, PloS one.

[19]  Gabriëlle H S Buitendijk,et al.  Education influences the role of genetics in myopia , 2013, European Journal of Epidemiology.

[20]  S. Cotter,et al.  Prevalence of myopia, hyperopia, and astigmatism in non-Hispanic white and Asian children: multi-ethnic pediatric eye disease study. , 2013, Ophthalmology.

[21]  W. Lee,et al.  Prevalence and risk factors for myopia in a rural Korean population. , 2013, Investigative ophthalmology & visual science.

[22]  Amanda N. French,et al.  Prevalence and 5- to 6-year incidence and progression of myopia and hyperopia in Australian schoolchildren. , 2013, Ophthalmology.

[23]  I. Morgan,et al.  Myopia and international educational performance , 2013, Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians.

[24]  Jing Sun,et al.  High prevalence of myopia and high myopia in 5060 Chinese university students in Shanghai. , 2012, Investigative ophthalmology & visual science.

[25]  O. Pärssinen The increased prevalence of myopia in Finland , 2012, Acta ophthalmologica.

[26]  Seang-Mei Saw,et al.  Worldwide prevalence and risk factors for myopia , 2012, Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians.

[27]  C. S. Lam,et al.  Prevalence of myopia among Hong Kong Chinese schoolchildren: changes over two decades , 2012, Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians.

[28]  P. Mitchell,et al.  Frequency, course, and impact of correctable visual impairment (uncorrected refractive error). , 2010, Survey of ophthalmology.

[29]  Lianhong Pi,et al.  Refractive Status and Prevalence of Refractive Errors in Suburban School-age Children , 2010, International journal of medical sciences.

[30]  Tien Yin Wong,et al.  Prevalence of refractive error in Singaporean Chinese children: the strabismus, amblyopia, and refractive error in young Singaporean Children (STARS) study. , 2010, Investigative ophthalmology & visual science.

[31]  F. Ferris,et al.  Increased prevalence of myopia in the United States between 1971-1972 and 1999-2004. , 2009, Archives of ophthalmology.

[32]  N. Congdon,et al.  A population-based study of visual impairment among pre-school children in Beijing: the Beijing study of visual impairment in children. , 2009, American journal of ophthalmology.

[33]  D. Friedman,et al.  Prevalence of refractive error among preschool children in an urban population: the Baltimore Pediatric Eye Disease Study. , 2009, Ophthalmology.

[34]  Y. Lai,et al.  The visual status of children ages 3 to 6 years in the vision screening program in Taiwan. , 2009, Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus.

[35]  Yingfeng Zheng,et al.  Refractive error and visual impairment in school children in rural southern China. , 2007, Ophthalmology.

[36]  Erez Onn,et al.  The changing prevalence of myopia in young adults: a 13-year series of population-based prevalence surveys. , 2005, Investigative ophthalmology & visual science.

[37]  L. Ellwein,et al.  Refractive error and visual impairment in school-age children in Gombak District, Malaysia. , 2005, Ophthalmology.

[38]  S. Chew,et al.  Prevalence, incidence, and progression of myopia of school children in Hong Kong. , 2004, Investigative ophthalmology & visual science.

[39]  Jingjing Xu,et al.  Refractive error and visual impairment in urban children in southern china. , 2004, Investigative ophthalmology & visual science.

[40]  D. Lam,et al.  Myopia progression among preschool Chinese children in Hong Kong. , 2004, Annals of the Academy of Medicine, Singapore.

[41]  D. Mutti,et al.  Refractive error and ethnicity in children. , 2003, Archives of ophthalmology.

[42]  G. Murthy,et al.  Refractive error in children in an urban population in New Delhi. , 2002, Investigative ophthalmology & visual science.

[43]  C. K. Hsiao,et al.  Epidemiologic study of the prevalence and severity of myopia among schoolchildren in Taiwan in 2000. , 2001, Journal of the Formosan Medical Association = Taiwan yi zhi.

[44]  A D Negrel,et al.  Refractive Error Study in Children: sampling and measurement methods for a multi-country survey. , 2000, American journal of ophthalmology.

[45]  L B Ellwein,et al.  Refractive Error Study in Children: results from La Florida, Chile. , 2000, American journal of ophthalmology.

[46]  L B Ellwein,et al.  Refractive Error Study in Children: results from Shunyi District, China. , 2000, American journal of ophthalmology.

[47]  H. Hirai,et al.  Prevalence of myopia and refractive changes in students from 3 to 17 years of age. , 1999, Survey of ophthalmology.

[48]  A. Blenkinsop World Health , 1957, Royal Society of Health journal.

[49]  J. A. Wilson MYOPIA , 1919, The British journal of ophthalmology.

[50]  Paul Mitchell,et al.  Epidemiology and disease burden of pathologic myopia and myopic choroidal neovascularization: an evidence-based systematic review. , 2014, American journal of ophthalmology.

[51]  Duan Cheng-ron,et al.  The Survival and Development Status of Floating Children in China:An Analysis of the Sixth Population Census Data , 2013 .

[52]  Prevalence of myopia and hyperopia in 6- to 72-month-old african american and Hispanic children: the multi-ethnic pediatric eye disease study. , 2010, Ophthalmology.

[53]  Serge Resnikoff,et al.  Global magnitude of visual impairment caused by uncorrected refractive errors in 2004. , 2008, Bulletin of the World Health Organization.

[54]  J. Katz,et al.  Incidence and progression of myopia in Singaporean school children. , 2005, Investigative ophthalmology & visual science.

[55]  S. Reitmanova Knowledge translation in health research: A novel approach to health sciences education , 2009, Medical education online.