Understanding the Semantic Structure of Human fMRI Brain Recordings with Formal Concept Analysis

We investigate whether semantic information related to object categories can be obtained from human fMRI BOLD responses with Formal Concept Analysis (FCA). While the BOLD response provides only an indirect measure of neural activity on a relatively coarse spatio-temporal scale, it has the advantage that it can be recorded from humans, who can be questioned about their perceptions during the experiment, thereby obviating the need of interpreting animal behavioral responses. Furthermore, the BOLD signal can be recorded from the whole brain simultaneously. In our experiment, a single human subject was scanned while viewing 72 gray-scale pictures of animate and inanimate objects in a target detection task. These pictures comprise the formal objects for FCA. We computed formal attributes by learning a hierarchical Bayesian classifier, which maps BOLD responses onto binary features, and these features onto object labels. The connectivity matrix between the binary features and the object labels can then serve as the formal context. In line with previous reports, FCA revealed a clear dissociation between animate and inanimate objects with the inanimate category also including plants. Furthermore, we found that the inanimate category was subdivided between plants and non-plants when we increased the number of attributes extracted from the BOLD response. FCA also allows for the display of organizational differences between high-level and low-level visual processing areas. We show that subjective familiarity and similarity ratings are strongly correlated with the attribute structure computed from the BOLD signal.