Determination of confidence intervals of metabolic fluxes estimated from stable isotope measurements.
暂无分享,去创建一个
Gregory Stephanopoulos | Maciek R Antoniewicz | G. Stephanopoulos | J. Kelleher | M. Antoniewicz | Joanne K Kelleher
[1] Marc K Hellerstein,et al. In vivo measurement of fluxes through metabolic pathways: the missing link in functional genomics and pharmaceutical research. , 2003, Annual review of nutrition.
[2] J. Katz,et al. Glucose production, recycling, and gluconeogenesis in normals and diabetics: a mass isotopomer [U-13C]glucose study. , 1996, The American journal of physiology.
[3] J E Bailey,et al. Metabolic flux analysis with a comprehensive isotopomer model in Bacillus subtilis. , 2001, Biotechnology and bioengineering.
[4] J. Nielsen,et al. Quantitative analysis of metabolic fluxes in Escherichia coli, using two-dimensional NMR spectroscopy and complete isotopomer models. , 1999, Journal of biotechnology.
[5] Philip E. Gill,et al. Numerical Linear Algebra and Optimization , 1991 .
[6] Kazuyuki Shimizu,et al. An improved method for statistical analysis of metabolic flux analysis using isotopomer mapping matrices with analytical expressions. , 2003, Journal of biotechnology.
[7] G. Stephanopoulos,et al. Systematic quantification of complex metabolic flux networks using stable isotopes and mass spectrometry. , 2003, European journal of biochemistry.
[8] Wolfgang M. Hartmann,et al. Computing the Moore-Penrose Inverse for the Covariance Matrix in Constrained Nonlinear Estimation , 1996, SIAM J. Optim..
[9] J. Wahren,et al. Limitations in estimating gluconeogenesis and Cori cycling from mass isotopomer distributions using [U-13C6]glucose. , 1998, American journal of physiology. Endocrinology and metabolism.
[10] A. Sunehag. The Role of Parenteral Lipids in Supporting Gluconeogenesis in Very Premature Infants , 2003, Pediatric Research.
[11] G. Stephanopoulos. Metabolic fluxes and metabolic engineering. , 1999, Metabolic engineering.
[12] W Wiechert,et al. A universal framework for 13C metabolic flux analysis. , 2001, Metabolic engineering.
[13] A. Sherry,et al. Evaluation of carbon flux and substrate selection through alternate pathways involving the citric acid cycle of the heart by 13C NMR spectroscopy. , 1988, The Journal of biological chemistry.
[14] J. Kelleher. Estimating gluconeogenesis with [U-13C]glucose: molecular condensation requires a molecular approach. , 1999, American journal of physiology. Endocrinology and metabolism.
[15] J. Nielsen,et al. Metabolic network analysis of Penicillium chrysogenum using (13)C-labeled glucose. , 2000, Biotechnology and bioengineering.
[16] T. Szyperski. Biosynthetically directed fractional 13C-labeling of proteinogenic amino acids. An efficient analytical tool to investigate intermediary metabolism. , 1995, European journal of biochemistry.
[17] J. Radziuk,et al. Measurement of gluconeogenesis and mass isotopomer analysis based on [U-13C]glucose. , 1999, American journal of physiology. Endocrinology and metabolism.
[18] Boris Kalitventzeff,et al. Sensitivity calculations and variance analysis in plant measurement reconciliation , 1996 .
[19] U. Sauer,et al. Metabolic fluxes in riboflavin-producing Bacillus subtilis , 1997, Nature Biotechnology.
[20] L. Foster. Rank and null space calculations using matrix decomposition without column interchanges , 1986 .
[21] J. Wahren,et al. Contributions of gluconeogenesis to glucose production in the fasted state. , 1996, The Journal of clinical investigation.
[22] J K Kelleher,et al. Applications of mass isotopomer analysis to nutrition research. , 1997, Annual review of nutrition.
[23] W. Wiechert,et al. Bidirectional reaction steps in metabolic networks: II. Flux estimation and statistical analysis. , 1997, Biotechnology and bioengineering.
[24] J. Heijnen,et al. Metabolic-flux analysis of Saccharomyces cerevisiae CEN.PK113-7D based on mass isotopomer measurements of (13)C-labeled primary metabolites. , 2005, FEMS yeast research.
[25] W Wiechert,et al. Bidirectional reaction steps in metabolic networks: IV. Optimal design of isotopomer labeling experiments. , 1999, Biotechnology and bioengineering.
[26] Jorge Nocedal,et al. An Interior Point Algorithm for Large-Scale Nonlinear Programming , 1999, SIAM J. Optim..
[27] T. Szyperski. Biosynthetically Directed Fractional 13C‐labeling of Proteinogenic Amino Acids , 1995 .
[28] J. Villadsen,et al. Modeling isotopomer distributions in biochemical networks using isotopomer mapping matrices. , 1997, Biotechnology and bioengineering.
[29] Sahm,et al. 13C tracer experiments and metabolite balancing for metabolic flux analysis: comparing two approaches , 1998, Biotechnology and bioengineering.
[30] W. J. Conover,et al. Practical Nonparametric Statistics , 1972 .
[31] P. Reeds,et al. Gluconeogenesis measured with [U-13C]glucose and mass isotopomer analysis of apoB-100 amino acids in pigs. , 1998, American journal of physiology. Endocrinology and metabolism.
[32] J. Kelleher,et al. Probing metabolic pathways with isotopic tracers: insights from mammalian metabolic physiology. , 2004, Metabolic engineering.
[33] W. Wiechert,et al. Bidirectional reaction steps in metabolic networks: III. Explicit solution and analysis of isotopomer labeling systems. , 1999, Biotechnology and bioengineering.
[34] A J Sinskey,et al. Metabolite and isotopomer balancing in the analysis of metabolic cycles: II. Applications. , 1999, Biotechnology and bioengineering.
[35] P. Verheijen,et al. Cumulative bondomers: a new concept in flux analysis from 2D [13C,1H] COSY NMR data. , 2002, Biotechnology and bioengineering.
[36] L. Groop,et al. Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. Evidence for multiple sites of insulin resistance. , 1989, The Journal of clinical investigation.