Granulocytic Sarcoma Presenting as Epidural Mass with Cord Compression in Aleukemic Patient Alösemik Hastada Omurilik Granülositik Basisi Yapan Sarkoma Epidural

Granulocytic sareoma (GS), constituted by the immature cells of myeloid serial, is arare, solid tumor. The tumor may be observed in the course of systemic myeloid leukemia. Occasionally, granulocytic sareoma may be observed without findings of acute leukemia. Authors report a 17-year-old female who had had spinal cord compression due to GS without evidence of leukemia. Up today, only 6 cas es have be en reported with paraparesis due to spinal epidural granulocytic sareoma without clinical symptomatology of leukemia. Laminectomy is mandatory for cases of cord compression and radiotherapy must be performed after the surgical intervention. For cases without spinal cord compression, chemotherapy and radiotherapy may be used together.

[1]  K. Miller,et al.  Granulocytic sarcoma (chloroma): sphenoidal sinus and paraspinal involvement as evaluated by CT and MR. , 1991, AJNR. American journal of neuroradiology.

[2]  D. Winfield,et al.  Epidural granulocytic sarcoma in acute myeloid leukemia with 8;21 translocation , 1988, Cancer.

[3]  J. Manning,et al.  Granulocytic sarcoma in nonleukemic patients , 1986, Cancer.

[4]  D. Saw,et al.  Extradural granulocytic sarcoma of the spine: A unique case of long survival after local therapy , 1986, American journal of hematology.

[5]  J. Bennett,et al.  Granulocytic sarcoma: A clinicopathologic study of 61 biopsied cases , 1981, Cancer.

[6]  D. Boggs,et al.  Spinal cord involvement in leukemia: A review of the literature and a case of Ph1 + acute myeloid leukemia presenting with a conus medullaris syndrome , 1981, Cancer.

[7]  J. Krause.  Granulocytic sarcoma preceding acute leukemia. A report of six cases , 1979, Cancer.

[8]  J. Adams,et al.  Pathology of Tumours of the Nervous System , 1978 .

[9]  H. Muss,et al.  Chloroma and other myeloblastic tumors. , 1973, Blood.

[10]  D. Mcgregor,et al.  Autopsy study of granulocytic sarcoma (chloroma) in patients with myelogenous leukemia, hiroshima‐nagasaki 1949‐1969 , 1973, Cancer.

[11]  R. Demaree,et al.  Granulocytic sarcoma (chloroma), two years preceding myelogenous leukemia , 1973, Cancer.

[12]  M. Walker,et al.  Central nervous system chloromas preceding acute leukemia by one year , 1970, Neurology.

[13]  A. B. Ragins,et al.  CHLOROMA: REPORT OF A CASE , 1950, Journal of neuropathology and experimental neurology.

[14]  G. Dock.  CHLOROMA AND ITS RELATION TO LEUKÆMIA , 1893 .

[15]  Observations on the Surgical Anatomy of the Head and Neck , 1816, The Medico-Chirurgical Journal and Review.

[16]  J. Davis,et al.  Granulocytic sarcoma presenting as an epidural mass with cord compression. , 1989, Neurosurgery.

[17]  O. Sugar.  Spinal cord involvement as the presenting symptom of acute monocytic leukemia. , 1988, Surgical neurology.

[18]  K. Mccarty,et al.  Chloroma (granulocytic sarcoma) without evidence of leukemia: facilitated light microscopic diagnosis. , 1980, Blood.

[19]  H. Rappaport,et al.  Tumors of the hematopoietic system , 1966 .

[20]  J. C. Belisario,et al.  Report on a case of? , 1954, Australian journal of dermatology.

[21]  T. Fahmi,et al.  A case of chloroma. , 1951, The Journal of the Egyptian Medical Association.