Cancer to bone: a fatal attraction
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T. Guise | Theresa A. Guise | Katherine N. Weilbaecher | K. Weilbaecher | Laurie K. McCauley | L. McCauley
[1] K. Pienta,et al. Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow. , 2011, The Journal of clinical investigation.
[2] R. Satcher,et al. Targeting prostate cancer angiogenesis through metastasis‐associated protein 1 (MTA1) , 2011, The Prostate.
[3] Yibin Kang,et al. Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells. , 2011, Cancer cell.
[4] Laurie J. Gay,et al. Contribution of platelets to tumour metastasis , 2011, Nature Reviews Cancer.
[5] P. Garnero,et al. Increased expression and serum levels of the stromal cell‐secreted protein periostin in breast cancer bone metastases , 2011, International journal of cancer.
[6] L. Bonewald,et al. The Amazing Osteocyte , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[7] K. Pienta,et al. Inhibitory Effects of Megakaryocytic Cells in Prostate Cancer Skeletal Metastasis , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[8] W. Semmler,et al. Sorafenib tosylate and paclitaxel induce anti-angiogenic, anti-tumour and anti-resorptive effects in experimental breast cancer bone metastases. , 2011, European journal of cancer.
[9] J. Schneider,et al. Integrins and bone metastasis: integrating tumor cell and stromal cell interactions. , 2011, Bone.
[10] F. Lecanda,et al. PDGFR signaling blockade in marrow stroma impairs lung cancer bone metastasis. , 2011, Cancer research.
[11] Y. Fujiwara,et al. Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: a randomized, double-blind study. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[12] A. Jensen,et al. The cathepsin K inhibitor odanacatib suppresses bone resorption in women with breast cancer and established bone metastases: results of a 4-week, double-blind, randomized, controlled trial. , 2010, Clinical breast cancer.
[13] David A. Cheresh,et al. Integrins in cancer: biological implications and therapeutic opportunities , 2010, Nature Reviews Cancer.
[14] D. Branstetter,et al. RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis , 2010, Nature.
[15] J. Nyman,et al. Inhibition of TGF‐β signaling by 1D11 antibody treatment increases bone mass and quality in vivo , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[16] J. Vykoukal,et al. Adipose tissue‐derived stem cells promote prostate tumor growth , 2010, The Prostate.
[17] M. Salto‐Tellez,et al. Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motility , 2010, Breast Cancer Research.
[18] R. Benezra,et al. Using the transcription factor inhibitor of DNA binding 1 to selectively target endothelial progenitor cells offers novel strategies to inhibit tumor angiogenesis and growth. , 2010, Cancer research.
[19] H. Dörr,et al. Novel activating mutations of the calcium-sensing receptor: the calcilytic NPS-2143 mitigates excessive signal transduction of mutant receptors. , 2010, The Journal of clinical endocrinology and metabolism.
[20] P. Bianco,et al. "Mesenchymal" stem cells in human bone marrow (skeletal stem cells): a critical discussion of their nature, identity, and significance in incurable skeletal disease. , 2010, Human gene therapy.
[21] W. Woodward,et al. Mesenchymal Stem Cells Promote Mammosphere Formation and Decrease E-Cadherin in Normal and Malignant Breast Cells , 2010, PloS one.
[22] Ben D. MacArthur,et al. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche , 2010, Nature.
[23] K. Hoek,et al. GLI2-mediated melanoma invasion and metastasis. , 2010, Journal of the National Cancer Institute.
[24] T. Yoneda,et al. Acid Activation of Trpv1 Leads to an Up-Regulation of Calcitonin Gene-related Peptide Expression in Dorsal Root Ganglion Neurons via the CaMK-CREB Cascade: A Potential Mechanism of Inflammatory Pain , 2010, Molecular biology of the cell.
[25] A. Chambers,et al. Role of the metastasis-promoting protein osteopontin in the tumour microenvironment , 2010, Journal of cellular and molecular medicine.
[26] G. Mundy,et al. Gr-1+CD11b+ Myeloid-Derived Suppressor Cells: Formidable Partners in Tumor Metastasis , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[27] R. Dreicer,et al. Zibotentan for the treatment of castrate-resistant prostate cancer , 2010, Expert opinion on investigational drugs.
[28] J. Folkman,et al. Platelet-derived thrombospondin-1 is a critical negative regulator and potential biomarker of angiogenesis. , 2010, Blood.
[29] Kohei Miyazono,et al. TGFβ signalling: a complex web in cancer progression , 2010, Nature Reviews Cancer.
[30] D. Heymann,et al. Interleukin‐34 is expressed by giant cell tumours of bone and plays a key role in RANKL‐induced osteoclastogenesis , 2010, The Journal of pathology.
[31] M. Korpal,et al. Targeting the transforming growth factor-beta signalling pathway in metastatic cancer. , 2010, European journal of cancer.
[32] M. Ellis,et al. Effect of zoledronic acid on disseminated tumour cells in women with locally advanced breast cancer: an open label, randomised, phase 2 trial. , 2010, The Lancet. Oncology.
[33] M. Futakuchi,et al. Matrix metalloproteinase (MMP)-13 regulates mammary tumor-induced osteolysis by activating MMP9 and transforming growth factor-beta signaling at the tumor-bone interface. , 2010, Cancer research.
[34] H. Sommer,et al. Effect of zoledronate on persisting isolated tumour cells in patients with early breast cancer. , 2010, Anticancer research.
[35] Joshua F. McMichael,et al. Genome Remodeling in a Basal-like Breast Cancer Metastasis and Xenograft , 2010, Nature.
[36] F. Bauduer,et al. Evidence of a colocalisation of osteoprotegerin (OPG) with von Willebrand factor (VWF) in platelets and megakaryocytes alpha granules. Studies from normal and grey platelets , 2010, British journal of haematology.
[37] J. Gralow,et al. Effects of denosumab in patients with bone metastases with and without previous bisphosphonate exposure , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[38] M. Seibel,et al. Vitamin D deficiency promotes human breast cancer growth in a murine model of bone metastasis. , 2010, Cancer Research.
[39] K. Pienta,et al. GAS6/AXL axis regulates prostate cancer invasion, proliferation, and survival in the bone marrow niche. , 2010, Neoplasia.
[40] R. Samant,et al. Osteopontin: an effector and an effect of tumor metastasis. , 2010, Current molecular medicine.
[41] L. Suva,et al. Tumor-Derived Syndecan-1 Mediates Distal Cross-Talk with Bone that Enhances Osteoclastogenesis , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[42] G. Stein,et al. Runx2 Association with Progression of Prostate Cancer in Patients: Mechanisms Mediating Bone Osteolysis and Osteoblastic Metastatic Lesions , 2009, Oncogene.
[43] M. Kacena,et al. Involvement of integrins α3β1 and α5β1 and glycoprotein IIb in megakaryocyte‐induced osteoblast proliferation , 2010, Journal of cellular biochemistry.
[44] David A. Cheresh,et al. Integrins in cancer: biological implications and therapeutic opportunities , 2010, Nature Reviews Cancer.
[45] H. Takayanagi. Osteoimmunology and the effects of the immune system on bone , 2009, Nature Reviews Rheumatology.
[46] J. Chirgwin,et al. Hypoxia and TGF-β Drive Breast Cancer Bone Metastases through Parallel Signaling Pathways in Tumor Cells and the Bone Microenvironment , 2009, PloS one.
[47] G. Stein,et al. Ectopic runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progression. , 2009, Cancer research.
[48] Qiongqing Wang,et al. ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis. , 2009, Genes & development.
[49] Xin Lu,et al. Imaging transforming growth factor-β signaling dynamics and therapeutic response in breast cancer bone metastasis , 2009, Nature Medicine.
[50] C. Boudot,et al. Extracellular calcium promotes the migration of breast cancer cells through the activation of the calcium sensing receptor. , 2009, Experimental cell research.
[51] Larry Norton,et al. Latent bone metastasis in breast cancer tied to Src-dependent survival signals. , 2009, Cancer cell.
[52] Julie L Prior,et al. Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100. , 2009, Blood.
[53] Xin Lu,et al. Efficient acquisition of dual metastasis organotropism to bone and lung through stable spontaneous fusion between MDA-MB-231 variants , 2009, Proceedings of the National Academy of Sciences.
[54] P. Dong,et al. Endocrine therapy plus zoledronic acid in premenopausal breast cancer. , 2009, The New England journal of medicine.
[55] Yi Tang,et al. TGF-β1-induced Migration of Bone Mesenchymal Stem Cells Couples Bone Resorption and Formation , 2009, Nature Medicine.
[56] D. Piwnica-Worms,et al. The bisphosphonate zoledronic acid decreases tumor growth in bone in mice with defective osteoclasts. , 2009, Bone.
[57] Charles P. Lin,et al. CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy. , 2009, Blood.
[58] R. Ritchie,et al. Pharmacologic Inhibition of the TGF-β Type I Receptor Kinase Has Anabolic and Anti-Catabolic Effects on Bone , 2009, PloS one.
[59] X. Mariette,et al. Randomized phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[60] K. Pienta,et al. A destructive cascade mediated by CCL2 facilitates prostate cancer growth in bone. , 2009, Cancer research.
[61] S. Stewart,et al. Senescent stromal-derived osteopontin promotes preneoplastic cell growth. , 2009, Cancer research.
[62] W. Ellis,et al. Disseminated Tumor Cells in Prostate Cancer Patients after Radical Prostatectomy and without Evidence of Disease Predicts Biochemical Recurrence , 2009, Clinical Cancer Research.
[63] D. Link,et al. Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization. , 2007, Blood.
[64] P. Clëzardin. Integrins in bone metastasis formation and potential therapeutic implications. , 2009, Current cancer drug targets.
[65] D. Hume,et al. Osteal macrophages: a new twist on coupling during bone dynamics. , 2008, Bone.
[66] Na Zhang,et al. Deletion of Vascular Endothelial Growth Factor in myeloid cells accelerates tumorigenesis , 2008, Nature.
[67] Hiroyuki Aburatani,et al. The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase , 2008, Nature Cell Biology.
[68] M. Colombo,et al. Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis. , 2008, Cancer research.
[69] F. Saad,et al. Advancing Treatment for Metastatic Bone Cancer: Consensus Recommendations from the Second Cambridge Conference , 2008, Clinical Cancer Research.
[70] L. Reynolds,et al. Integrins: the keys to unlocking angiogenesis. , 2008, Arteriosclerosis, thrombosis, and vascular biology.
[71] M. Klagsbrun,et al. Calcification of multipotent prostate tumor endothelium. , 2008, Cancer cell.
[72] R. Mamillapalli,et al. Switching of G-protein Usage by the Calcium-sensing Receptor Reverses Its Effect on Parathyroid Hormone-related Protein Secretion in Normal Versus Malignant Breast Cells* , 2008, Journal of Biological Chemistry.
[73] R. Vessella,et al. Histopathological assessment of prostate cancer bone osteoblastic metastases. , 2008, The Journal of urology.
[74] Evan T. Keller,et al. Type I collagen receptor (α2β1) signaling promotes prostate cancer invasion through RhoC GTPase , 2008 .
[75] Hiroki Wakabayashi,et al. Decorin Suppresses Bone Metastasis in a Breast Cancer Cell Line , 2008, Oncology.
[76] F. Marshall,et al. Receptor activator of NF-κB Ligand (RANKL) expression is associated with epithelial to mesenchymal transition in human prostate cancer cells , 2008, Cell Research.
[77] E. Keller,et al. Prostate cancer induces bone metastasis through Wnt-induced bone morphogenetic protein-dependent and independent mechanisms. , 2008, Cancer research.
[78] F. Saad,et al. Normalization of bone markers is associated with improved survival in patients with bone metastases from solid tumors and elevated bone resorption receiving zoledronic acid , 2008, Cancer.
[79] E. Morgan,et al. APT102, a novel adpase, cooperates with aspirin to disrupt bone metastasis in mice , 2008, Journal of cellular biochemistry.
[80] R. Weinberg,et al. Systemic Endocrine Instigation of Indolent Tumor Growth Requires Osteopontin , 2008, Cell.
[81] I. Weissman,et al. Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth , 2008, Proceedings of the National Academy of Sciences.
[82] A. Chakraborty,et al. Fusion of tumour cells with bone marrow-derived cells: a unifying explanation for metastasis , 2008, Nature Reviews Cancer.
[83] A. Teti,et al. Inhibition of protein kinase c-Src as a therapeutic approach for cancer and bone metastases. , 2008, Anti-cancer agents in medicinal chemistry.
[84] W. Zou,et al. RelB is the NF-κB subunit downstream of NIK responsible for osteoclast differentiation , 2008, Proceedings of the National Academy of Sciences.
[85] V. Castronovo,et al. Small integrin-binding ligand N-linked glycoproteins (SIBLINGs): multifunctional proteins in cancer , 2008, Nature Reviews Cancer.
[86] D. Nolan,et al. Endothelial Progenitor Cells Control the Angiogenic Switch in Mouse Lung Metastasis , 2008, Science.
[87] P. Frankel,et al. Biologic Markers of Angiogenesis: Circulating Endothelial Cells in Patients with Advanced Malignancies Treated on Phase I Protocol with Metronomic Chemotherapy and Celecoxib , 2008, Cancer investigation.
[88] L. Reynolds,et al. The Keys to Unlocking Angiogenesis , 2008 .
[89] J. Chirgwin,et al. Molecular biology of bone metastasis. , 2008, Molecular cancer therapeutics.
[90] Z. Werb,et al. Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma. , 2007, Cancer research.
[91] G. Prud’homme. Pathobiology of transforming growth factor β in cancer, fibrosis and immunologic disease, and therapeutic considerations , 2007, Laboratory Investigation.
[92] F. Journé,et al. Increased Dickkopf-1 expression in breast cancer bone metastases , 2007, British Journal of Cancer.
[93] S. Vukicevic,et al. Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer. , 2007, Cancer research.
[94] Antoinette Wetterwald,et al. BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo. , 2007, The American journal of pathology.
[95] L. Ylagan,et al. Isolation and Molecular Profiling of Bone Marrow Micrometastases Identifies TWIST1 as a Marker of Early Tumor Relapse in Breast Cancer Patients , 2007, Clinical Cancer Research.
[96] E. Morgan,et al. Disruption of CXCR4 enhances osteoclastogenesis and tumor growth in bone , 2007, Proceedings of the National Academy of Sciences.
[97] G. Donofrio,et al. Production of Wnt inhibitors by myeloma cells: potential effects on canonical Wnt pathway in the bone microenvironment. , 2007, Cancer research.
[98] R. Zellweger,et al. BONE MORPHOGENETIC PROTEINS IN CLINICAL APPLICATIONS , 2007, ANZ journal of surgery.
[99] Weilin Zhou,et al. Platelet-activating factor induces ovine fetal pulmonary venous smooth muscle cell proliferation: role of epidermal growth factor receptor transactivation. , 2007, American journal of physiology. Heart and circulatory physiology.
[100] T. Yoneda,et al. Hypoxia and hypoxia-inducible factor-1 expression enhance osteolytic bone metastases of breast cancer. , 2007, Cancer research.
[101] K. Trinkaus,et al. Granulocyte colony-stimulating factor enhances bone tumor growth in mice in an osteoclast-dependent manner. , 2007, Blood.
[102] K. Mohammad,et al. Stable overexpression of Smad7 in human melanoma cells impairs bone metastasis. , 2007, Cancer research.
[103] O. Stephens,et al. Dickkopf homolog 1 mediates endothelin-1-stimulated new bone formation. , 2007, Molecular endocrinology.
[104] T. Plesner,et al. Osteoclast nuclei of myeloma patients show chromosome translocations specific for the myeloma cell clone: a new type of cancer–host partnership? , 2007, The Journal of pathology.
[105] K. Pienta,et al. Expression and activation of αvβ3 integrins by SDF‐1/CXC12 increases the aggressiveness of prostate cancer cells , 2007 .
[106] T. Giordano,et al. NF-κB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF , 2007, Nature Medicine.
[107] M. Colombo,et al. The terminology issue for myeloid-derived suppressor cells. , 2007, Cancer research.
[108] V. Castronovo,et al. Low dentin matrix protein 1 expression correlates with skeletal metastases development in breast cancer patients and enhances cell migratory capacity in vitro , 2007, Breast Cancer Research and Treatment.
[109] M. Rogers,et al. Molecular Cancer Mechanisms of Osteopontin and Cd44 as Metastatic Principles in Prostate Cancer Cells , 2006 .
[110] A. Griffioen,et al. Monocyte/macrophage infiltration in tumors: modulators of angiogenesis , 2006, Journal of leukocyte biology.
[111] Y. Kadono,et al. Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction , 2006, The Journal of experimental medicine.
[112] J. Compston,et al. Osteoclast formation and bone resorption are inhibited by megakaryocytes. , 2006, Bone.
[113] Robert D. Schreiber,et al. Interferons, immunity and cancer immunoediting , 2006, Nature Reviews Immunology.
[114] E. Morgan,et al. Skeletal Complications of Breast Cancer Therapies , 2006, Clinical Cancer Research.
[115] A. Jimeno,et al. Targeting Bone Metastasis in Prostate Cancer with Endothelin Receptor Antagonists , 2006, Clinical Cancer Research.
[116] J. Chirgwin,et al. Basic Mechanisms Responsible for Osteolytic and Osteoblastic Bone Metastases , 2006, Clinical Cancer Research.
[117] D. Clohisy,et al. Biology of Bone Cancer Pain , 2006, Clinical Cancer Research.
[118] A. Schneider,et al. Extracellular calcium as a candidate mediator of prostate cancer skeletal metastasis. , 2006, Cancer research.
[119] E. Keller,et al. Type I Collagen Receptor (α2β1) Signaling Promotes the Growth of Human Prostate Cancer Cells within the Bone , 2006 .
[120] L. Naldini,et al. Role of haematopoietic cells and endothelial progenitors in tumour angiogenesis. , 2006, Biochimica et biophysica acta.
[121] Ming Zhao,et al. The hedgehog signaling molecule Gli2 induces parathyroid hormone-related peptide expression and osteolysis in metastatic human breast cancer cells. , 2006, Cancer research.
[122] Ari Elson,et al. Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells , 2006, Nature Medicine.
[123] O. MacDougald,et al. Role of wnts in prostate cancer bone metastases , 2006, Journal of cellular biochemistry.
[124] V. Castronovo,et al. Expression of dentin sialophosphoprotein in human prostate cancer and its correlation with tumor aggressiveness , 2006, International journal of cancer.
[125] J. Hopper,et al. Parathyroid hormone-related protein localization in breast cancers predict improved prognosis. , 2006, Cancer research.
[126] Xiyun Deng,et al. CXCL12/CXCR4 signaling activates Akt‐1 and MMP‐9 expression in prostate cancer cells: The role of bone microenvironment‐associated CXCL12 , 2006, The Prostate.
[127] L. Ratner,et al. HTLV-1 Tax transgenic mice develop spontaneous osteolytic bone metastases prevented by osteoclast inhibition. , 2005, Blood.
[128] S. Rafii,et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche , 2005, Nature.
[129] Toshio Matsumoto,et al. Myeloma cells suppress bone formation by secreting a soluble Wnt inhibitor, sFRP-2. , 2005, Blood.
[130] Wei He,et al. Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[131] Yi Lu,et al. Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism. , 2005, Cancer research.
[132] G. Karsenty,et al. Cooperative Interactions between Activating Transcription Factor 4 and Runx2/Cbfa1 Stimulate Osteoblast-specific Osteocalcin Gene Expression* , 2005, Journal of Biological Chemistry.
[133] F. Saad,et al. Predictive value of bone resorption and formation markers in cancer patients with bone metastases receiving the bisphosphonate zoledronic acid. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[134] L. Suva,et al. Expression of heparanase by primary breast tumors promotes bone resorption in the absence of detectable bone metastases. , 2005, Cancer research.
[135] Y. Ko,et al. Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size , 2005, The Journal of experimental medicine.
[136] Dennis C. Sgroi,et al. Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion , 2005, Cell.
[137] Tomoyuki Shirai,et al. MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL. , 2005, Cancer cell.
[138] A. Vignery. Macrophage fusion: are somatic and cancer cells possible partners? , 2005, Trends in cell biology.
[139] K. Pienta,et al. Bone turnover mediates preferential localization of prostate cancer in the skeleton. , 2005, Endocrinology.
[140] G. Stein,et al. Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[141] Abraham Schneider,et al. Skeletal Localization and Neutralization of the SDF‐1(CXCL12)/CXCR4 Axis Blocks Prostate Cancer Metastasis and Growth in Osseous Sites In Vivo , 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[142] M. Kitajima,et al. The Relationship Between Bone Metastasis from Human Breast Cancer and Integrin αvβ3 Expression , 2005 .
[143] R. Ritchie,et al. TGF-regulates the mechanical properties and composition of bone matrix , 2005 .
[144] A. Yang,et al. CXCR4 knockdown by small interfering RNA abrogates breast tumor growth in vivo , 2005, Cancer Gene Therapy.
[145] P. Clézardin,et al. Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer. , 2004, The Journal of clinical investigation.
[146] U. Choi,et al. CXCR4‐Transgene Expression Significantly Improves Marrow Engraftment of Cultured Hematopoietic Stem Cells , 2004, Stem cells.
[147] D. Piwnica-Worms,et al. CXCR4 Regulates Growth of Both Primary and Metastatic Breast Cancer , 2004, Cancer Research.
[148] G. Karsenty,et al. ATF4, the Osteoblast Accumulation of Which Is Determined Post-translationally, Can Induce Osteoblast-specific Gene Expression in Non-osteoblastic Cells* , 2004, Journal of Biological Chemistry.
[149] M. Andreeff,et al. Mesenchymal stem cells: potential precursors for tumor stroma and targeted-delivery vehicles for anticancer agents. , 2004, Journal of the National Cancer Institute.
[150] K. Moriyama,et al. Osteoclasts enhance myeloma cell growth and survival via cell-cell contact: a vicious cycle between bone destruction and myeloma expansion. , 2004, Blood.
[151] Paul J. Williams,et al. Anti-alpha4 integrin antibody suppresses the development of multiple myeloma and associated osteoclastic osteolysis. , 2004, Blood.
[152] E. Brown,et al. Calcium-sensing receptor activation stimulates parathyroid hormone-related protein secretion in prostate cancer cells: role of epidermal growth factor receptor transactivation. , 2004, Bone.
[153] P. Frenette,et al. The integrin αMβ2 anchors hematopoietic progenitors in the bone marrow during enforced mobilization , 2004 .
[154] R. Korah,et al. Integrin α5β1 Promotes Survival of Growth-Arrested Breast Cancer Cells , 2004, Cancer Research.
[155] P. Sassone-Corsi,et al. ATF4 Is a Substrate of RSK2 and an Essential Regulator of Osteoblast Biology Implication for Coffin-Lowry Syndrome , 2004, Cell.
[156] G. Roodman. Mechanisms of bone metastasis. , 2004, Discovery medicine.
[157] S. Karlsson,et al. Overexpression of CXCR4 on human CD34+ progenitors increases their proliferation, migration, and NOD/SCID repopulation. , 2004, Blood.
[158] Andrés Hidalgo,et al. Integrin α4β1 involvement in stromal cell-derived factor-1α-promoted myeloma cell transendothelial migration and adhesion: role of cAMP and the actin cytoskeleton in adhesion , 2004 .
[159] J. Platt,et al. Melanoma × macrophage hybrids with enhanced metastatic potential , 1998, Clinical & Experimental Metastasis.
[160] N. Clarke,et al. Primary prostatic epithelial cell binding to human bone marrow stroma and the role of a2b1 integrin , 1997, Clinical & Experimental Metastasis.
[161] R. Korah,et al. Integrin alpha5beta1 promotes survival of growth-arrested breast cancer cells: an in vitro paradigm for breast cancer dormancy in bone marrow. , 2004, Cancer research.
[162] M. Waltham,et al. Transfection of MDA-MB-231 human breast carcinoma cells with bone sialoprotein (BSP) stimulates migration and invasion in vitro and growth of primary and secondary tumors in nude mice , 2004, Clinical & Experimental Metastasis.
[163] Daphne Vassiliou,et al. Differential expression of osteopontin and bone sialoprotein in bone metastasis of breast and prostate carcinoma , 2004, Clinical & Experimental Metastasis.
[164] F. Zhan,et al. The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. , 2003, The New England journal of medicine.
[165] N. Harbeck,et al. Detection and clinical implications of early systemic tumor cell dissemination in breast cancer. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[166] M. Rogers. New insights into the molecular mechanisms of action of bisphosphonates. , 2003, Current pharmaceutical design.
[167] P. Clézardin,et al. Angiostatin Inhibits Bone Metastasis Formation in Nude Mice through a Direct Anti-osteoclastic Activity* , 2003, Journal of Biological Chemistry.
[168] M. Tomasson,et al. Platelet and osteoclast β3 integrins are critical for bone metastasis , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[169] D. Scadden,et al. Osteoblastic cells regulate the haematopoietic stem cell niche , 2003, Nature.
[170] Haiyang Huang,et al. Identification of the haematopoietic stem cell niche and control of the niche size , 2003, Nature.
[171] J. Chirgwin,et al. A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[172] S. Teitelbaum,et al. Genetic regulation of osteoclast development and function , 2003, Nature Reviews Genetics.
[173] R. Vessella,et al. Prostate cancer expression of runt‐domain transcription factor Runx2, a key regulator of osteoblast differentiation and function , 2003, The Prostate.
[174] C. Cordon-Cardo,et al. A multigenic program mediating breast cancer metastasis to bone. , 2003, Cancer cell.
[175] K. Pienta,et al. Expression of CXCR4 and CXCL12 (SDF‐1) in human prostate cancers (PCa) in vivo , 2003, Journal of cellular biochemistry.
[176] K. Pienta,et al. Stromal factors involved in prostate carcinoma metastasis to bone , 2003, Cancer.
[177] G. Mundy. Metastasis: Metastasis to bone: causes, consequences and therapeutic opportunities , 2002, Nature Reviews Cancer.
[178] Noam Brown,et al. The role of tumour‐associated macrophages in tumour progression: implications for new anticancer therapies , 2002, The Journal of pathology.
[179] J. Deng,et al. The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation , 2002, Cell.
[180] I. Holen,et al. Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma. , 2001, Blood.
[181] Flemming Melsen,et al. Cancellous Bone Remodeling Occurs in Specialized Compartments Lined by Cells Expressing Osteoblastic Markers , 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[182] L. Radbruch,et al. Symptoms during cancer pain treatment following WHO-guidelines: a longitudinal follow-up study of symptom prevalence, severity and etiology , 2001, Pain.
[183] H. Iguchi,et al. Increased incidence of bone metastases in hepatocellular carcinoma , 2001, European journal of gastroenterology & hepatology.
[184] R. Coleman. Metastatic bone disease: clinical features, pathophysiology and treatment strategies. , 2001, Cancer treatment reviews.
[185] M. Noda,et al. Osteopontin Deficiency Reduces Experimental Tumor Cell Metastasis to Bone and Soft Tissues , 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[186] T. Mcclanahan,et al. Involvement of chemokine receptors in breast cancer metastasis , 2001, Nature.
[187] E. Brown,et al. Expression of extracellular calcium-sensing receptor in human osteoblastic MG-63 cell line. , 2001, American journal of physiology. Cell physiology.
[188] E. Brown,et al. Extracellular calcium-sensing receptor expression and its potential role in regulating parathyroid hormone-related peptide secretion in human breast cancer cell lines. , 2000, Endocrinology.
[189] Paul J. Williams,et al. Cell–cell contact between marrow stromal cells and myeloma cells via VCAM-1 and α4β1-integrin enhances production of osteoclast-stimulating activity , 2000 .
[190] P Delmas,et al. Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases. , 2000, Cancer research.
[191] P. Mantyh,et al. Osteoprotegerin blocks bone cancer-induced skeletal destruction, skeletal pain and pain-related neurochemical reorganization of the spinal cord , 2000, Nature Medicine.
[192] A. McEwan,et al. Use of radionuclides for the palliation of bone metastases. , 2000, Seminars in radiation oncology.
[193] T. Dimpfl,et al. Cytokeratin-positive cells in the bone marrow and survival of patients with stage I, II, or III breast cancer. , 2000, The New England journal of medicine.
[194] H Sommer,et al. Lack of effect of adjuvant chemotherapy on the elimination of single dormant tumor cells in bone marrow of high-risk breast cancer patients. , 2000, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[195] T. Papayannopoulou,et al. Mechanisms of stem-/progenitor-cell mobilization: the anti-VLA-4 paradigm. , 2000, Seminars in hematology.
[196] T. Yoneda. Cellular and molecular basis of preferential metastasis of breast cancer to bone , 2000, Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association.
[197] W. Dougall,et al. RANK is essential for osteoclast and lymph node development. , 1999, Genes & development.
[198] L. Chung,et al. Osteomimetic properties of prostate cancer cells: A hypothesis supporting the predilection of prostate cancer metastasis and growth in the bone environment , 1999, The Prostate.
[199] T. Martin,et al. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. , 1999, Endocrine reviews.
[200] W. Dalton,et al. Cell Adhesion Mediated Drug Resistance (CAM-DR): Role of Integrins and Resistance to Apoptosis in Human Myeloma Cell Lines , 1999 .
[201] R Wieser,et al. TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development. , 1999, The Journal of clinical investigation.
[202] A. Sundan,et al. Hepatocyte growth factor (HGF) induces interleukin-11 secretion from osteoblasts: a possible role for HGF in myeloma-associated osteolytic bone disease. , 1999, Blood.
[203] W. Dalton,et al. Cell adhesion mediated drug resistance (CAM-DR): role of integrins and resistance to apoptosis in human myeloma cell lines. , 1999, Blood.
[204] K. Luzzi,et al. Multistep nature of metastatic inefficiency: dormancy of solitary cells after successful extravasation and limited survival of early micrometastases. , 1998, The American journal of pathology.
[205] K. Pienta,et al. Preferential adhesion of prostate cancer cells to a human bone marrow endothelial cell line. , 1998, Journal of the National Cancer Institute.
[206] S. Braun,et al. Re: Micrometastatic breast cancer cells in bone marrow at primary surgery: prognostic value in comparison with nodal status. , 1996, Journal of the National Cancer Institute.
[207] Makoto Sato,et al. Targeted Disruption of Cbfa1 Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts , 1997, Cell.
[208] B F Boyce,et al. Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis. , 1996, The Journal of clinical investigation.
[209] Y. Takada,et al. Induction of experimental bone metastasis in mice by transfection of integrin α4β1 into tumor cells , 1996 .
[210] R. Holle,et al. Micrometastatic breast cancer cells in bone marrow at primary surgery: prognostic value in comparison with nodal status. , 1996, Journal of the National Cancer Institute.
[211] J. Nelson,et al. Identification of endothelin–1 in the pathophysiology of metastatic adenocarcinoma of the prostate , 1995, Nature Medicine.
[212] P. Allavena,et al. Effects of granulocyte‐monocyte colony‐stimulating factor (GM‐CSF) on expression of adhesion molecules and production of cytokines in blood monocytes and ovarian cancer‐associated macrophages , 1995, International journal of cancer.
[213] J. Dipersio,et al. Integrins and adhesive receptors in normal and leukemic CD34+ progenitor cells: potential regulatory checkpoints for cellular traffic. , 1994, Leukemia & lymphoma.
[214] M. Gleave,et al. Acceleration of human prostate cancer growth in vivo by factors produced by prostate and bone fibroblasts. , 1991, Cancer research.
[215] N. Clarke,et al. Morphometric evidence for bone resorption and replacement in prostate cancer. , 1991, British journal of urology.
[216] B. Zetter,et al. Stimulation of human prostatic carcinoma cell growth by factors present in human bone marrow. , 1989, The Journal of clinical investigation.
[217] I. Fidler,et al. Metastasis: Quantitative Analysis of Distribution and Fate of Tumor Emboli Labeled With 125I-5-Iodo-2′ -deoxyuridine , 1970 .
[218] E. Butt,et al. Palindromic unilateral renal purpura: an explanation for renal hematuria of obscure origin. , 1952, Transactions. American Urological Association. Western Section.
[219] Y. Oshika,et al. P-glycoprotein-mediated acquired multidrug resistance of human lung cancer cells in vivo. , 1996, British Journal of Cancer.