Synthesis of ubiquinone and cholesterol in human fibroblasts: regulation of a branched pathway.

[1]  M. Brown,et al.  Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase. , 1978, The Journal of biological chemistry.

[2]  P. Edwards,et al.  Control of 3-hydroxy-3-methylglutaryl coenzyme A reductase by endogenously synthesized sterols in vitro and in vivo. , 1977, The Journal of biological chemistry.

[3]  B. Ed,et al.  Biochemistry of Polyisoprenoid Biosynthesis , 1976 .

[4]  M. Brown,et al.  The LDL pathway in human fibroblasts: a receptor-mediated mechanism for the regulation of cholesterol metabolism. , 1976, Current topics in cellular regulation.

[5]  J. Nordstrom,et al.  Regulation of HMG-CoA reductase. , 1976, Advances in lipid research.

[6]  M. Brown,et al.  Suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and inhibition of growth of human fibroblasts by 7-ketocholesterol. , 1974, The Journal of biological chemistry.

[7]  B. Trumpower,et al.  Studies on ubiquinone. Demonstration of the total biosynthesis of ubiquinone-9 in rat liver mitochondria. , 1974, The Journal of biological chemistry.

[8]  M. Brown,et al.  Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia. , 1974, The Journal of biological chemistry.

[9]  H. Rudney,et al.  3-Polyprenyl-4-hydroxybenzoate synthesis in the inner membrane of mitochondria from p-hydroxybenzoate and isopentenylpyrophosphate. A demonstration of isoprenoid synthesis in rat liver mitochondria. , 1972, The Journal of biological chemistry.

[10]  R. Olson,et al.  Enhancement of ubiquinone-9 biosynthesis in rat-liver slices by exogenous mevalonate. , 1972, European journal of biochemistry.

[11]  R. Olson,et al.  The effect of exogenous cholesterol on the synthesis in vivo of cholesterol, ubiquinone, and squalene in rat liver. , 1967, Biochemical and biophysical research communications.

[12]  G. Popják,et al.  Substrate Stereochemistry in Squalene Biosynthesis , 1966 .

[13]  R. Gould,et al.  Sites of control of hepatic cholesterol biosynthesis. , 1966, Journal of lipid research.

[14]  R. Olson,et al.  Studies on coenzyme Q. The biosynthesis of coenzyme Q9 in rat tissue slices. , 1966, The Journal of biological chemistry.

[15]  R. Olson Biosynthesis of ubiquinones in animals. , 1966, Vitamins and hormones.

[16]  W. J. Dyer,et al.  A rapid method of total lipid extraction and purification. , 1959, Canadian journal of biochemistry and physiology.

[17]  O. H. Lowry,et al.  Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.