Application of a portable microprocessor-based system for electrophysiological field testing of neurotoxicity.

A portable microprocessor-based system designated PEARL II has been developed for neurotoxicity testing in human populations. PEARL II provides a flexible and powerful data acquisition capability to record sensory evoked potentials (auditory, visual and somatosensory), event-related slow potentials (CNV, P300) and behavioral measures. PEARL II has been mounted in a mobile laboratory to facilitate field testing. Data obtained in pediatric lead studies are provided for illustration.