A Hypoxia-Targeted Boron Neutron Capture Therapy Agent for the Treatment of Glioma

[1]  Yong Wang,et al.  MicroRNA-370 suppresses the progression and proliferation of human astrocytoma and glioblastoma by negatively regulating β-catenin and causing activation of FOXO3a. , 2017, Experimental and therapeutic medicine.

[2]  J. Arbiser,et al.  Tris DBA palladium overcomes hypoxia-mediated drug resistance in multiple myeloma , 2015, Leukemia & lymphoma.

[3]  A. Azab,et al.  Advancements in Tumor Targeting Strategies for Boron Neutron Capture Therapy , 2015, Pharmaceutical Research.

[4]  Afaf R. Genady,et al.  New functionalized mercaptoundecahydrododecaborate derivatives for potential application in boron neutron capture therapy: synthesis, characterization and dynamic visualization in cells. , 2015, European journal of medicinal chemistry.

[5]  H. Wheeler,et al.  Molecular Heterogeneity in Glioblastoma: Potential Clinical Implications , 2015, Front. Oncol..

[6]  N. Dowson,et al.  Hypoxia imaging in gliomas with 18F-fluoromisonidazole PET: toward clinical translation. , 2015, Seminars in nuclear medicine.

[7]  A. Azab,et al.  The Role of Hypoxia and Exploitation of the Hypoxic Environment in Hematologic Malignancies , 2014, Molecular Cancer Research.

[8]  I. Císařová,et al.  Alpha (α-) and beta (β-carboranyl-C-deoxyribosides: syntheses, structures and biological evaluation. , 2014, European journal of medicinal chemistry.

[9]  A. Azab,et al.  Molecularly Targeted Therapies in Multiple Myeloma , 2014, Leukemia research and treatment.

[10]  D. Tang,et al.  Cancer stem cells and radioresistance , 2014, International journal of radiation biology.

[11]  G. Kabalka,et al.  Biodistribution and Subcellular Localization of an Unnatural Boron-Containing Amino Acid (Cis-ABCPC) by Imaging Secondary Ion Mass Spectrometry for Neutron Capture Therapy of Melanomas and Gliomas , 2013, PloS one.

[12]  Shinji Kawabata,et al.  Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer , 2012, Radiation oncology.

[13]  N. Hosmane,et al.  Boron and Gadolinium Neutron Capture Therapy for Cancer Treatment , 2012 .

[14]  Rui Huang,et al.  Glioma derived isocitrate dehydrogenase-2 mutations induced up-regulation of HIF-1α and β-catenin signaling: possible impact on glioma cell metastasis and chemo-resistance. , 2012, The international journal of biochemistry & cell biology.

[15]  K. Zink,et al.  The impact of direct aperture optimization on plan quality and efficiency in complex head and neck IMRT , 2012, Radiation oncology.

[16]  Naren L. Banik,et al.  Drug Resistance in Glioblastoma: A Mini Review , 2012, Neurochemical Research.

[17]  N. Hosmane.  Boron Science : New Technologies and Applications , 2011 .

[18]  D. Lyden,et al.  Resisting arrest: a switch from angiogenesis to vasculogenesis in recurrent malignant gliomas. , 2010, The Journal of clinical investigation.

[19]  L. Collette,et al.  EORTC trial 11001: distribution of two 10B‐compounds in patients with squamous cell carcinoma of head and neck, a translational research/phase 1 trial , 2009, Journal of cellular and molecular medicine.

[20]  V. Amberger-Murphy.  Hypoxia helps glioma to fight therapy. , 2009, Current cancer drug targets.

[21]  R. Mirimanoff,et al.  Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. , 2009, The Lancet. Oncology.

[22]  A. Matsumura,et al.  Boron neutron capture therapy for glioblastoma. , 2008, Cancer letters.

[23]  L. Pellettieri,et al.  An investigation of boron neutron capture therapy for recurrent glioblastoma multiforme , 2008, Acta neurologica Scandinavica.

[24]  L. Collette,et al.  Uptake of two 10B‐compounds in liver metastases of colorectal adenocarcinoma for extracorporeal irradiation with boron neutron capture therapy (EORTC Trial 11001) , 2007, International journal of cancer.

[25]  M. Pisarev,et al.  Boron neutron capture therapy in cancer: past, present and future. , 2007, Arquivos brasileiros de endocrinologia e metabologia.

[26]  K. Ono,et al.  First clinical case of boron neutron capture therapy for head and neck malignancies using 18F‐BPA PET , 2006, Head & neck.

[27]  Margaret Wrensch,et al.  Epidemiology and molecular pathology of glioma , 2006, Nature Clinical Practice Neurology.

[28]  W. Golde,et al.  A rapid, simple, and humane method for submandibular bleeding of mice using a lancet , 2005, Lab Animal.

[29]  M. Vicente,et al.  Boron Neutron Capture Therapy of Cancer: Current Status and Future Prospects , 2005, Clinical Cancer Research.

[30]  W. Sauerwein,et al.  Boron neutron capture therapy for glioblastoma multiforme , 2004, Pharmacy World and Science.

[31]  Martin J. van den Bent,et al.  Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. , 2005, The New England journal of medicine.

[32]  R. Cabrini,et al.  Biodistribution studies of boronophenylalanine-fructose in melanoma and brain tumor patients in Argentina. , 2004, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[33]  M. Bergmann,et al.  Cell type selective accumulation of mercaptoundecahydro-closo-dodecaborate (BSH) in glioblastoma multiforme , 2003, Acta Neurochirurgica.

[34]  D. Brat,et al.  Malignant Glioma Physiology: Cellular Response to Hypoxia and Its Role in Tumor Progression , 2003, Annals of Internal Medicine.

[35]  M. Hawthorne,et al.  A critical assessment of boron target compounds for boron neutron capture therapy , 2003, Journal of Neuro-Oncology.

[36]  C. Aquino-Parsons,et al.  Comparison between the comet assay and pimonidazole binding for measuring tumour hypoxia , 2000, British Journal of Cancer.

[37]  P. Wesseling,et al.  Hypoxia in a human intracerebral glioma model. , 2000, Journal of neurosurgery.

[38]  A S Kennedy,et al.  Pimonidazole: a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in cervical carcinoma. , 1998, Gynecologic oncology.

[39]  R. Barth,et al.  The Chemistry of Neutron Capture Therapy , 1998 .

[40]  A. J. Varghese,et al.  Hypoxia-dependent reduction of 1-(2-nitro-1-imidazolyl)-3-methoxy-2-propanol by Chinese hamster ovary cells and KHT tumor cells in vitro and in vivo. , 1976, Cancer research.

[41]  Michael Weller,et al.  Standards of care for treatment of recurrent glioblastoma--are we there yet? , 2013, Neuro-oncology.

[42]  M. Campone,et al.  Hypoxia and the malignant glioma microenvironment: regulation and implications for therapy. , 2009, Current molecular pharmacology.

[43]  A. Azab,et al.  Chapter 5 - Boron neutron capture therapy , 2005 .