Patterned magnetic traps for magnetophoretic assembly and actuation of microrotor pumps

We demonstrate a microscopic magnetic rotor pump for fluidic channels whose components are assembled in situ and powered by weak external magnetic fields (<150 Oe). A platform of patterned Permalloy microdisks and microcavities provided for the transport, trapping, and rotation of the superparamagnetic spherical microrotors. Parallel actuation of several rotors without direct physical link to external energy sources, tunable rotation speeds, and reversible drive torques offers significant advantages over macroscopic techniques to control flow within microfluidic devices. The effectiveness of trapping and transporting magnetic nanoparticles by the disks illustrate scalability to smaller, submicrometer sized devices.

[1]  Jonathan Leach,et al.  An optically driven pump for microfluidics. , 2006, Lab on a chip.

[2]  R. Fox,et al.  Classical Electrodynamics, 3rd ed. , 1999 .

[3]  M. Donahue,et al.  Integrated microfluidic isolation platform for magnetic particle manipulation in biological systems , 2004 .

[4]  G. Whitesides.  The origins and the future of microfluidics , 2006, Nature.

[5]  D. A. Dunnett.  Classical Electrodynamics , 2020, Nature.

[6]  S. Quake,et al.  Monolithic microfabricated valves and pumps by multilayer soft lithography. , 2000, Science.

[7]  Juan G. Santiago,et al.  A review of micropumps , 2004 .

[8]  R. Sooryakumar,et al.  Manipulation of magnetically labeled and unlabeled cells with mobile magnetic traps. , 2010, Biophysical journal.

[9]  Hui S Son,et al.  Traveling wave magnetophoresis for high resolution chip based separations. , 2007, Lab on a chip.

[10]  Alex Terray,et al.  Microfluidic Control Using Colloidal Devices , 2002, Science.

[11]  David W. M. Marr,et al.  Field-mediated self-assembly and actuation of highly parallel microfluidic devices , 2006 .

[12]  Aaron Chen,et al.  Simultaneous magnetic manipulation and fluorescent tracking of multiple individual hybrid nanostructures. , 2010, Nano letters.

[13]  N. Osterman,et al.  Magnetically actuated microrotors with individual pumping speed and direction control , 2009 .

[14]  D W M Marr,et al.  In situ assembly of linked geometrically coupled microdevices , 2008, Proceedings of the National Academy of Sciences.

[15]  Nicole Pamme,et al.  Magnetism and microfluidics. , 2006, Lab on a chip.

[16]  M J Donahue,et al.  OOMMF User's Guide, Version 1.0 , 1999 .