Review of the impact of molecular analysis on the therapy of medulloblastoma
暂无分享,去创建一个
[1] Jennifer L. Hadley,et al. Efficacy of Carboplatin and Isotretinoin in Children With High-risk Medulloblastoma: A Randomized Clinical Trial From the Children's Oncology Group. , 2021, JAMA oncology.
[2] Jennifer L. Hadley,et al. Children's Oncology Group Phase III Trial of Reduced-Dose and Reduced-Volume Radiotherapy With Chemotherapy for Newly Diagnosed Average-Risk Medulloblastoma , 2021, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[3] T. Merchant,et al. Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03). , 2021, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[4] C. Hawkins,et al. MBCL-25. PILOT STUDY OF A SURGERY AND CHEMOTHERAPY-ONLY APPROACH IN THE UPFRONT THERAPY OF CHILDREN WITH WNT-POSITIVE STANDARD RISK MEDULLOBLASTOMA: UPDATED OUTCOMES , 2020, Neuro-Oncology.
[5] C. Sommer,et al. Nonmetastatic Medulloblastoma of Early Childhood: Results From the Prospective Clinical Trial HIT-2000 and An Extended Validation Cohort. , 2020, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[6] V. Hovestadt,et al. Medulloblastomics revisited: biological and clinical insights from thousands of patients , 2019, Nature Reviews Cancer.
[7] M. Souweidane,et al. Phase II Study of Nonmetastatic Desmoplastic Medulloblastoma in Children Younger Than 4 Years of Age: A Report of the Children's Oncology Group (ACNS1221). , 2019, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[8] Claire M. Faltermeier,et al. Survival of infants ≤24 months of age with brain tumors: A population-based study using the SEER database , 2019, PloS one.
[9] Jill S Barnholtz-Sloan,et al. CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2011-2015. , 2018, Neuro-oncology.
[10] David T. W. Jones,et al. Risk-adapted therapy for young children with medulloblastoma (SJYC07): therapeutic and molecular outcomes from a multicentre, phase 2 trial. , 2018, The Lancet. Oncology.
[11] Roland Eils,et al. Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort , 2018 .
[12] D. Johnston,et al. Survival Following Tumor Recurrence in Children With Medulloblastoma , 2018, Journal of pediatric hematology/oncology.
[13] Charles Y. Lin,et al. NRL and CRX Define Photoreceptor Identity and Reveal Subgroup-Specific Dependencies in Medulloblastoma. , 2018, Cancer cell.
[14] S. Kaste,et al. Irreversible growth plate fusions in children with medulloblastoma treated with a targeted hedgehog pathway inhibitor , 2017, Oncotarget.
[15] Sirintra Nakjang,et al. Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study , 2017, The Lancet. Oncology.
[16] A. Goldenberg,et al. Intertumoral Heterogeneity within Medulloblastoma Subgroups. , 2017, Cancer cell.
[17] Martin J. Aryee,et al. OTX2 Activity at Distal Regulatory Elements Shapes the Chromatin Landscape of Group 3 Medulloblastoma. , 2017, Cancer discovery.
[18] G. Gustafsson,et al. Relapse patterns and outcome after relapse in standard risk medulloblastoma: a report from the HIT-SIOP-PNET4 study , 2016, Journal of Neuro-Oncology.
[19] M. Kool,et al. Risk stratification of childhood medulloblastoma in the molecular era: the current consensus , 2016, Acta Neuropathologica.
[20] Gary D. Bader,et al. Divergent clonal selection dominates medulloblastoma at recurrence , 2016, Nature.
[21] D. Mitra,et al. SIOP PODC adapted treatment recommendations for standard‐risk medulloblastoma in low and middle income settings , 2015, Pediatric blood & cancer.
[22] Florence I. Raynaud,et al. Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease , 2015, Cancer cell.
[23] Gary D Bader,et al. Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma , 2014, Nature.
[24] Toshihiro Kumabe,et al. Cytogenetic prognostication within medulloblastoma subgroups. , 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[25] Roland Eils,et al. Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition. , 2014, Cancer cell.
[26] Benjamin J. Raphael,et al. Mutational landscape and significance across 12 major cancer types , 2013, Nature.
[27] Gary D Bader,et al. Comprehensive identification of mutational cancer driver genes across 12 tumor types , 2013, Scientific Reports.
[28] F. Béby,et al. The homeobox gene Otx2 in development and disease. , 2013, Experimental eye research.
[29] Matthew J. Betts,et al. Dissecting the genomic complexity underlying medulloblastoma , 2012, Nature.
[30] Steven J. M. Jones,et al. Subgroup-specific structural variation across 1,000 medulloblastoma genomes , 2012, Nature.
[31] Jill P. Mesirov,et al. MEDULLOBLASTOMA EXOME SEQUENCING UNCOVERS SUBTYPE-SPECIFIC SOMATIC MUTATIONS , 2012, Nature.
[32] Elaine R. Mardis,et al. Novel mutations target distinct subgroups of medulloblastoma , 2012, Nature.
[33] Stefan M. Pfister,et al. The clinical implications of medulloblastoma subgroups , 2012, Nature Reviews Neurology.
[34] Scott L. Pomeroy,et al. Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas , 2012, Acta Neuropathologica.
[35] David T. W. Jones,et al. Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations , 2012, Cell.
[36] Scott L. Pomeroy,et al. Molecular subgroups of medulloblastoma: the current consensus , 2011, Acta Neuropathologica.
[37] S. Croul,et al. Adult medulloblastoma comprises three major molecular variants. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[38] J. Mesirov,et al. Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[39] Arie Perry,et al. Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups , 2011, Acta Neuropathologica.
[40] Yiai Tong,et al. Subtypes of medulloblastoma have distinct developmental origins , 2010, Nature.
[41] Axel Benner,et al. Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[42] Hong Wang,et al. PRDM6 is enriched in vascular precursors during development and inhibits endothelial cell proliferation, survival, and differentiation. , 2008, Journal of molecular and cellular cardiology.
[43] D. Ellison,et al. Wnt/Wingless Pathway Activation and Chromosome 6 Loss Characterise a Distinct Molecular Sub-Group of Medulloblastomas Associated with a Favourable Prognosis , 2006, Cell cycle.
[44] T. Merchant,et al. Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial. , 2006, The Lancet. Oncology.
[45] O. McDonald,et al. PRISM/PRDM6, a Transcriptional Repressor That Promotes the Proliferative Gene Program in Smooth Muscle Cells , 2006, Molecular and Cellular Biology.
[46] Claire L Weston,et al. beta-Catenin status predicts a favorable outcome in childhood medulloblastoma: the United Kingdom Children's Cancer Study Group Brain Tumour Committee. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[47] Helen Baines,et al. Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice. , 2004, Cancer cell.
[48] R. Gilbertson,et al. Medulloblastoma: signalling a change in treatment. , 2004, The Lancet. Oncology.
[49] A. Simeone. Otx1 and Otx2 in the development and evolution of the mammalian brain , 1998, The EMBO journal.
[50] C. Worster-Drought,et al. Medulloblastoma (?) , 1931, Methods in Molecular Biology.
[51] David Hogg,et al. Mutations in SUFU predispose to medulloblastoma , 2002, Nature Genetics.