Challenges in the Development of Reference Materials for Protein Toxins

[1]  G. Griffiths,et al.  Characterization of ricin heterogeneity by electrospray mass spectrometry, capillary electrophoresis, and resonant mirror. , 2000, Analytical biochemistry.

[2]  J. Uhr,et al.  The toxicity of chemically deglycosylated ricin A-chain in mice. , 1992, International journal of immunopharmacology.

[3]  H. Schimmel,et al.  Quantification of protein calibrants by amino acid analysis using isotope dilution mass spectrometry. , 2011, Analytical biochemistry.

[4]  E. Gaunt,et al.  Staphylococcal Enterotoxin B as a Biological Weapon: Recognition, Management, and Surveillance of Staphylococcal Enterotoxin , 2006 .

[5]  S. Kirchner,et al.  Real-Time Cytotoxicity Assay for Rapid and Sensitive Detection of Ricin from Complex Matrices , 2012, PloS one.

[6]  M. Ishiguro,et al.  Isolation and Characterization of Ricin E from Castor Beans , 1977 .

[7]  S. Simon,et al.  Recommended Immunological Assays to Screen for Ricin-Containing Samples , 2015, Toxins.

[8]  J. Krupp,et al.  A comparison of biological activity of commercially available purified native botulinum neurotoxin serotypes A1 to F1 in vitro, ex vivo, and in vivo , 2018, Pharmacology research & perspectives.

[9]  Suzanne R. Kalb,et al.  Recommended Mass Spectrometry-Based Strategies to Identify Botulinum Neurotoxin-Containing Samples , 2015, Toxins.

[10]  L. Seeberger,et al.  Botulinum Toxins Policy , 2018 .

[11]  R. Zeleny,et al.  An International Proficiency Test to Detect, Identify and Quantify Ricin in Complex Matrices , 2015, Toxins.

[12]  K. Blennow,et al.  Commutability of the certified reference materials for the standardization of β-amyloid 1-42 assay in human cerebrospinal fluid: lessons for tau and β-amyloid 1-40 measurements , 2018, Clinical chemistry and laboratory medicine.

[13]  Suzanne R. Kalb,et al.  Mass Spectrometric Detection of Bacterial Protein Toxins and Their Enzymatic Activity , 2015, Toxins.

[14]  C. Robb The analysis of abrin in food and beverages , 2015 .

[15]  R. Zeleny,et al.  Organization and ELISA-Based Results of the First Proficiency Testing to Evaluate the Ability of European Union Laboratories to Detect Staphylococcal Enterotoxin Type B (SEB) in Buffer and Milk , 2016, Toxins.

[16]  H. Emteborg,et al.  Certified reference materials for testing of the presence/absence of Staphylococcus aureus enterotoxin A (SEA) in cheese , 2016, Analytical and Bioanalytical Chemistry.

[17]  R D Josephs,et al.  Impurity identification and determination for the peptide hormone angiotensin I by liquid chromatography–high-resolution tandem mass spectrometry and the metrological impact on value assignments by amino acid analysis , 2013, Analytical and Bioanalytical Chemistry.

[18]  A. Rummel The long journey of botulinum neurotoxins into the synapse. , 2015, Toxicon : official journal of the International Society on Toxinology.

[19]  H. Emteborg,et al.  Assessment of commutability for candidate certified reference material ERM-BB130 “chloramphenicol in pork” , 2010, Analytical and bioanalytical chemistry.

[20]  R. Hawley,et al.  Biological Toxins: Safety and Science , 2006 .

[21]  N. Tumer,et al.  N‐glycosylation Does Not Affect the Catalytic Activity of Ricin A Chain but Stimulates Cytotoxicity by Promoting Its Transport Out of the Endoplasmic Reticulum , 2012, Traffic.

[22]  R. Zeleny,et al.  Biological toxins of potential bioterrorism risk: Current status of detection and identification technology , 2016 .

[23]  R. Zeleny,et al.  Generation and Characterization of Six Recombinant Botulinum Neurotoxins as Reference Material to Serve in an International Proficiency Test , 2015, Toxins.

[24]  J. Klimentova,et al.  Proteomic Methods of Detection and Quantification of Protein Toxins , 2018, Toxins.

[25]  K. Blennow,et al.  Mass spectrometry-based candidate reference measurement procedure for quantification of amyloid-β in cerebrospinal fluid. , 2014, Clinical chemistry.

[26]  R. Zeleny,et al.  Influence of the approach to calibration on the accuracy and the traceability of certified values in certified reference materials , 2012 .

[27]  R. Vijayaraghavan,et al.  Purification, characterization and toxicity profile of ricin isoforms from castor beans. , 2010, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[28]  D. Pappin,et al.  The primary sequence of Ricinus communis agglutinin. Comparison with ricin. , 1985, The Journal of biological chemistry.

[29]  R. F. Weaver,et al.  Characterization of a cDNA encoding ricin E, a hybrid ricin-Ricinus communis agglutinin gene from the castor plant Ricinus communis , 1987, Plant Molecular Biology.

[30]  M. Dorner,et al.  Complexity of botulinum neurotoxins: challenges for detection technology. , 2013, Current topics in microbiology and immunology.

[31]  Hendrik Emons,et al.  An approach for more precise statements of metrological traceability on reference material certificates , 2010 .

[32]  A. Hulst,et al.  Forensic identification of neat ricin and of ricin from crude castor bean extracts by mass spectrometry. , 2005, Analytical chemistry.

[33]  Reuven Rasooly,et al.  In vitro cell-based assay for activity analysis of staphylococcal enterotoxin A in food. , 2009, FEMS immunology and medical microbiology.

[34]  Suzanne R. Kalb,et al.  Recommended Mass Spectrometry-Based Strategies to Identify Ricin-Containing Samples , 2015, Toxins.

[35]  D. Schieltz,et al.  Quantification of ricin, RCA and comparison of enzymatic activity in 18 Ricinus communis cultivars by isotope dilution mass spectrometry , 2015, Toxicon : official journal of the International Society on Toxinology.

[36]  A.M.H. van der Veen,et al.  Homogeneity and stability of reference materials , 2001 .

[37]  T. Araki,et al.  The complete amino acid sequence of the B-chain of ricin E isolated from small-grain castor bean seeds. Ricin E is a gene recombination product of ricin D and Ricinus communis agglutinin. , 1987, Biochimica et biophysica acta.

[38]  I. Gary Resnick,et al.  Safety and Health Considerations for Conducting Work with Biological Toxins , 2001 .

[39]  Heather L. Stang,et al.  Analysis of active ricin and castor bean proteins in a ricin preparation, castor bean extract, and surface swabs from a public health investigation. , 2011, Forensic science international.

[40]  E. Ezan,et al.  Detection of functional ricin by immunoaffinity and liquid chromatography-tandem mass spectrometry. , 2007, Analytical chemistry.

[41]  Werner Luginbühl,et al.  Qualitative and Quantitative Detection of Botulinum Neurotoxins from Complex Matrices: Results of the First International Proficiency Test , 2015, Toxins.

[42]  G. Moran,et al.  Threats in bioterrorism. II: CDC category B and C agents. , 2002, Emergency medicine clinics of North America.

[43]  C. Franzini Commutability of reference materials in clinical chemistry. , 1993, Journal of the International Federation of Clinical Chemistry.

[44]  J. Trojanowski,et al.  Qualification of a surrogate matrix-based absolute quantification method for amyloid-β₄₂ in human cerebrospinal fluid using 2D UPLC-tandem mass spectrometry. , 2014, Journal of Alzheimer's disease : JAD.

[45]  R. Zeleny,et al.  Characterization of Ricin and R. communis Agglutinin Reference Materials , 2015, Toxins.

[46]  Martin Skiba,et al.  Replacing the mouse bioassay for diagnostics and potency testing of botulinum neurotoxins – progress and challenges , 2018 .

[47]  Sarah C. Jenson,et al.  Ricin‐like proteins from the castor plant do not influence liquid chromatography‐mass spectrometry detection of ricin in forensically relevant samples , 2017, Toxicon : official journal of the International Society on Toxinology.

[48]  Jean Pauwels,et al.  The study of the stability of reference materials by isochronous measurements , 1998 .

[49]  R. Tierney,et al.  Recommended Immunological Strategies to Screen for Botulinum Neurotoxin-Containing Samples , 2015, Toxins.

[50]  S. Worbs,et al.  Ricinus communis Intoxications in Human and Veterinary Medicine-A Summary of Real Cases , 2011, Toxins.

[51]  R. Spooner,et al.  Ricin Trafficking in Cells , 2015, Toxins.

[52]  M. Quaglia,et al.  Investigating microwave hydrolysis for the traceable quantification of peptide standards using gas chromatography-mass spectrometry. , 2011, Analytical biochemistry.

[53]  R. G. Darling,et al.  Threats in bioterrorism. I: CDC category A agents. , 2002, Emergency medicine clinics of North America.

[54]  Mohsin Khan,et al.  Differential toxicity profile of ricin isoforms correlates with their glycosylation levels. , 2011, Toxicology.

[55]  M. Fountoulakis,et al.  Hydrolysis and amino acid composition of proteins. , 1998, Journal of chromatography. A.

[56]  H. Bigalke,et al.  Botulinum Neurotoxins: Qualitative and Quantitative Analysis Using the Mouse Phrenic Nerve Hemidiaphragm Assay (MPN) , 2015, Toxins.

[57]  M. Quaglia,et al.  Concept paper on SI value assignment of purity - Model for the classification of peptide/protein purity determinations , 2017 .

[58]  Hendrik Emons,et al.  Reference materials: terminology and use. Can't one see the forest for the trees? , 2004 .

[59]  D. Franz,et al.  RICIN TOXIN , 2000 .

[60]  T. Krakauer,et al.  The staphylococcal enterotoxin (SE) family , 2013, Virulence.

[61]  Suzanne R. Kalb,et al.  Historical Perspectives and Guidelines for Botulinum Neurotoxin Subtype Nomenclature , 2017, Toxins.