A robust algorithm for project portfolio selection problem using real options valuation

Purpose The principal concern of organization managers in the global rivalry of commerce environment is how to select the project portfolio among available projects. In this matter, organizations should consider the uncertainty intrinsic in the projects regarding an appropriate valuation technique within an optimization framework. In this research, the purpose of this paper is to formulate using a robust optimization algorithm to deal with the complexities and uncertainty inherent in the construction of the project portfolio. Design/methodology/approach First, a general mathematical formulation is presented, which in compound real options valuation is highlighted. This formulation gives managerial flexibility by correcting the deficiency of traditional discounted cash flow technique that excludes any form of flexibility. Then, considering a limitation on budget of the organization, an integer programming formulation to maximize the n-fold compound options for project portfolio selection is proposed. Finally, a robust optimization model is developed along with the robust combinatorial optimization algorithm, which is effective for solving problems under uncertainty. Findings Sensitivity analysis showed that projects in later phases of development, having survived several phases of pre-clinical and clinical tests, are worth more because they are more likely to pertain to business. However, the investment costs related to each project during development phases limit the number of projects that a company can bring to their final portfolio. Additionally, the analysis of conservatism level represented how project managers can quite easily determine their risk attitude and the corresponding portfolio composition. From a managerial point of view, the proposed framework is very useful because it requires only financial estimates. Hence, the proposed decision support tool can assist research and development (R&D) project managers in the pharmaceutical industry for making decisions. Originality/value The first is the application of the n-fold compound options on portfolio of R&D projects and the employment of compound options value of a project portfolio as an objective function. The second one is a mathematical formulation of these concepts and solving it by the robust combinatorial optimization algorithm. The literature is lacking in the application of the robust combinatorial optimization algorithm to R&D project portfolio selection based on the generalized n-fold compound option model of Cassimon et al. (2004). Every framework from calculation of the n-fold compound option to solving robust combinatorial algorithm is programmed in Matlab software, since it can be used as a business support tool.

[1]  Jianmin He,et al.  A geometric Levy model for n-fold compound option pricing in a fuzzy framework , 2016, J. Comput. Appl. Math..

[2]  G. L. Nigro,et al.  Open innovation: A real option to restore value to the biopharmaceutical R&D , 2014 .

[3]  K. Jensen,et al.  The use of options theory to value research in the service sector , 2001 .

[4]  Yu-Lin Huang,et al.  Valuation of multi‐stage BOT projects involving dedicated asset investments: a sequential compound option approach , 2009 .

[5]  Enrico Pennings,et al.  Evaluating pharmaceutical R&D under technical and economic uncertainty , 2011, Eur. J. Oper. Res..

[6]  Giovanni Villani,et al.  Valuation of R&D Sequential Exchange Options Using Monte Carlo Approach , 2009 .

[7]  Hemantha S. B. Herath,et al.  MULTI-STAGE CAPITAL INVESTMENT OPPORTUNITIES AS COMPOUND REAL Options , 2002 .

[8]  Danny Cassimon,et al.  The valuation of a NDA using a 6-fold compound option , 2004 .

[9]  Danny Cassimon,et al.  Compound Real Option Valuation with Phase-Specific Volatility: A Multi-Phase Mobile Payments Case Study , 2010 .

[10]  Shantanu Dutta,et al.  Management Views on Real Options in Capital Budgeting , 2010 .

[11]  J. Jensen,et al.  A real options approach to biotechnology investment policy-the case of developing a Campylobacter vaccine to poultry. , 2016, Preventive veterinary medicine.

[12]  R. Geske THE VALUATION OF COMPOUND OPTIONS , 1979 .

[13]  Manfred Perlitz,et al.  Real options valuation: the new frontier in R&D project evaluation? , 1999 .

[14]  Johnathan Mun,et al.  Real options analysis : tools and techniques for valuing strategic investments and decisions , 2012 .

[15]  Chris Marnay,et al.  Real options valuation of US federal renewable energy research, development, demonstration, and deployment , 2005 .

[16]  F. Black,et al.  The Pricing of Options and Corporate Liabilities , 1973, Journal of Political Economy.

[17]  Hamid R. Nemati,et al.  A robust R&D project portfolio optimization model for pharmaceutical contract research organizations , 2014 .

[18]  Christer Carlsson,et al.  A fuzzy approach to R&D project portfolio selection , 2007, Int. J. Approx. Reason..

[19]  Chen Chen,et al.  Robust portfolio selection for index tracking , 2012, Comput. Oper. Res..

[20]  L. Trigeorgis Real Options: Managerial Flexibility and Strategy in Resource Allocation , 1996 .

[21]  Parag C. Pendharkar,et al.  A decision-making framework for justifying a portfolio of IT projects , 2014 .

[22]  Costas D. Maranas,et al.  Real Options Based Analysis of Optimal Pharmaceutical Research and Development Portfolios , 2002 .

[23]  Eduardo S. Schwartz Patents and R&D as Real Options , 2003 .

[24]  Richard L. Shockley,et al.  The Option Value Of An Early-Stage Biotechnology Investment , 2002 .

[25]  Paolo Toth,et al.  A note on the Bertsimas & Sim algorithm for robust combinatorial optimization problems , 2013, 4OR.

[26]  Majid Rafiee,et al.  A scenario tree approach to multi-period project selection problem using real-option valuation method , 2011 .

[27]  Eduardo S. Schwartz,et al.  Investment Under Uncertainty. , 1994 .

[28]  Minghe Sun,et al.  Robust optimization for interactive multiobjective programming with imprecise information applied to R&D project portfolio selection , 2014, Eur. J. Oper. Res..

[29]  Lei Zhu A simulation based real options approach for the investment evaluation of nuclear power , 2012, Comput. Ind. Eng..

[30]  Valuation of Compound Real Options for Investments in Innovative Projects in Pharmaceutical Industry , 2015 .

[31]  Giovanni Villani Valuation of R&D Investment Opportunities Using the Least-Squares Monte Carlo Method , 2014 .

[32]  Suvankar Ghosh,et al.  Complex compound option models - Can practitioners truly operationalize them? , 2012, Eur. J. Oper. Res..

[33]  S. Sahu,et al.  A Real Option based Six Sigma project evaluation and selection model , 2011 .

[34]  Mohammad Modarres,et al.  A Robust Optimization Approach to R&D Project Selection , 2009 .

[35]  Juite Wang,et al.  A fuzzy set approach for R&D portfolio selection using a real options valuation model , 2007 .

[36]  Rainer Andergassen,et al.  Valuation of N-stage Investments Under Jump-Diffusion Processes , 2012 .

[37]  M. Zhang,et al.  A real option model for renewable energy policy evaluation with application to solar PV power generation in China , 2014 .

[38]  Alireza Aliahmadi,et al.  Application of Gray Systems and Fuzzy Sets in Combination with Real Options Theory in Project Portfolio Management , 2014 .

[39]  Amelia C. Regan,et al.  Network-based real option models , 2011 .

[40]  Bastian Hauschild,et al.  Modeling sequential R&D investments: a binomial compound option approach , 2015 .

[41]  Francis A. Longstaff,et al.  Valuing American Options by Simulation: A Simple Least-Squares Approach , 2001 .

[42]  Reza Ramazani Khorshid-Doust,et al.  A method of project selection based on capital asset pricing theories in a framework of mean–semideviation behavior , 2008 .

[43]  Melvyn Sim,et al.  Robust discrete optimization and network flows , 2003, Math. Program..

[44]  Danny Cassimon,et al.  Incorporating Technical Risk in Compound Real Option Models to Value a Pharmaceutical R&D Licensing Opportunity , 2010 .

[45]  Marta Biancardi,et al.  Robust Monte Carlo Method for R&D Real Options Valuation , 2017 .

[46]  Stefan Spinler,et al.  Real option valuation of public sector R&D investments with a down-and-out barrier option , 2014 .

[47]  Mohammad Modarres,et al.  A practical R&D selection model using fuzzy pay-off method , 2012 .