Toll-Like Receptor 4 Mediates Intracellular Signaling Without TNF-a Release in Response to Cryptococcus neoformans Polysaccharide Capsule

[1]  S. Levitz,et al.  Chloroquine Interferes with Lipopolysaccharide-Induced TNF-α Gene Expression by a Nonlysosomotropic Mechanism1 , 2000, The Journal of Immunology.

[2]  S. Vogel,et al.  Cutting Edge: Repurification of Lipopolysaccharide Eliminates Signaling Through Both Human and Murine Toll-Like Receptor 21 , 2000, The Journal of Immunology.

[3]  B. Monks,et al.  Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide. , 2000, The Journal of clinical investigation.

[4]  D. Golenbock,et al.  The CD14 ligands lipoarabinomannan and lipopolysaccharide differ in their requirement for Toll-like receptors. , 1999, Journal of immunology.

[5]  D. Golenbock,et al.  Toll-like Receptor 2 Functions as a Pattern Recognition Receptor for Diverse Bacterial Products* , 1999, The Journal of Biological Chemistry.

[6]  K. Knudtson,et al.  The p38 mitogen-activated protein kinase is required for NF-kappaB-dependent gene expression. The role of TATA-binding protein (TBP). , 1999, The Journal of biological chemistry.

[7]  A. Aderem,et al.  The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens , 1999, Nature.

[8]  D. Golenbock,et al.  Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis. , 1999, Journal of immunology.

[9]  M. Ashburner,et al.  Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila. , 1999, Science.

[10]  S. Akira,et al.  Unresponsiveness of MyD88-deficient mice to endotoxin. , 1999, Immunity.

[11]  D. Golenbock,et al.  Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2. , 1999, Journal of immunology.

[12]  P. Godowski,et al.  The toll of innate immunity on microbial pathogens. , 1999, The New England journal of medicine.

[13]  M. Gaestel,et al.  MAPKAP kinase 2 is essential for LPS-induced TNF-α biosynthesis , 1999, Nature Cell Biology.

[14]  F. Gusovsky,et al.  Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction* , 1999, The Journal of Biological Chemistry.

[15]  G. Hunninghake,et al.  Both Erk and p38 kinases are necessary for cytokine gene transcription. , 1999, American journal of respiratory cell and molecular biology.

[16]  M. Rothe,et al.  Bacterial Lipopolysaccharide Activates Nuclear Factor-κB through Interleukin-1 Signaling Mediators in Cultured Human Dermal Endothelial Cells and Mononuclear Phagocytes* , 1999, The Journal of Biological Chemistry.

[17]  M. Rothe,et al.  Human Toll-like Receptor 2 Confers Responsiveness to Bacterial Lipopolysaccharide , 1998, The Journal of experimental medicine.

[18]  C. Gerard.  For whom the bell tolls , 1998 .

[19]  D. Golenbock,et al.  Construction of a lipopolysaccharide reporter cell line and its use in identifying mutants defective in endotoxin, but not TNF-alpha, signal transduction. , 1998, Journal of immunology.

[20]  A. Casadevall,et al.  Involvement of C3a and C5a in Interleukin-8 Secretion by Human Polymorphonuclear Cells in Response to Capsular Material of Cryptococcus neoformans , 1998, Infection and Immunity.

[21]  F. Bistoni,et al.  Role of the capsule in microglial cell-Cryptococcus neoformans interaction: impairment of antifungal activity but not of secretory functions. , 1998, Medical mycology.

[22]  S. Saccani,et al.  The Human Toll Signaling Pathway: Divergence of Nuclear Factor κB and JNK/SAPK Activation Upstream of Tumor Necrosis Factor Receptor–associated Factor 6 (TRAF6) , 1998, The Journal of experimental medicine.

[23]  D. Letourneur,et al.  Fluorescent and radiolabeling of polysaccharides: binding and internalization experiments on vascular cells. , 1998, Journal of biomedical materials research.

[24]  J. Swantek,et al.  Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNF-alpha) translation: glucocorticoids inhibit TNF-alpha translation by blocking JNK/SAPK , 1997, Molecular and cellular biology.

[25]  T. Molitor,et al.  Phagocytosis of nonopsonized Cryptococcus neoformans by swine microglia involves CD14 receptors. , 1997, Clinical immunology and immunopathology.

[26]  T. Harrison,et al.  Induction of human immunodeficiency virus type 1 expression in monocytic cells by Cryptococcus neoformans and Candida albicans. , 1997, The Journal of infectious diseases.

[27]  C. Janeway,et al.  A human homologue of the Drosophila Toll protein signals activation of adaptive immunity , 1997, Nature.

[28]  G. Teti,et al.  Interleukin-6 production by human monocytes stimulated with Cryptococcus neoformans components , 1997, Infection and immunity.

[29]  J. Murphy,et al.  Cryptococcal polysaccharides bind to CD18 on human neutrophils , 1997, Infection and immunity.

[30]  J. Verhoef,et al.  Cryptococcus neoformans and cryptococcal glucuronoxylomannan, galactoxylomannan, and mannoprotein induce different levels of tumor necrosis factor alpha in human peripheral blood mononuclear cells , 1997, Infection and immunity.

[31]  G. Mancuso,et al.  Tumor necrosis factor-inducing activities of Cryptococcus neoformans components , 1996, Infection and immunity.

[32]  B. Klein,et al.  Virulence Factors of Medically Important Fungi , 1996 .

[33]  A. Casadevall,et al.  Polysaccharide antigen in brain tissue of AIDS patients with cryptococcal meningitis. , 1996, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[34]  A. Casadevall,et al.  Immunohistochemical localization of capsular polysaccharide antigen in the central nervous system cells in cryptococcal meningoencephalitis. , 1996, The American journal of pathology.

[35]  D. Golenbock,et al.  Effects of interleukin-10 on human peripheral blood mononuclear cell responses to Cryptococcus neoformans, Candida albicans, and lipopolysaccharide , 1996, Infection and immunity.

[36]  J. Murphy,et al.  Cryptococcal polysaccharides induce L-selectin shedding and tumor necrosis factor receptor loss from the surface of human neutrophils. , 1996, The Journal of clinical investigation.

[37]  J. Curtis,et al.  Down-regulation of the afferent phase of T cell-mediated pulmonary inflammation and immunity by a high melanin-producing strain of Cryptococcus neoformans. , 1995, Journal of immunology.

[38]  A. Casadevall,et al.  Variation in the structure of glucuronoxylomannan in isolates from patients with recurrent cryptococcal meningitis , 1995, Infection and immunity.

[39]  A. Casadevall,et al.  Enhancement of HIV type 1 infectivity in vitro by capsular polysaccharide of Cryptococcus neoformans and Haemophilus influenzae. , 1994, AIDS research and human retroviruses.

[40]  D. Golenbock,et al.  Production of tumor necrosis factor alpha in human leukocytes stimulated by Cryptococcus neoformans , 1994, Infection and immunity.

[41]  M. Freeman,et al.  Surface expression of human CD14 in Chinese hamster ovary fibroblasts imparts macrophage-like responsiveness to bacterial endotoxin. , 1993, The Journal of biological chemistry.

[42]  A. Casadevall,et al.  Enhancement of HIV-1 infection by the capsular polysaccharide of Cryptococcus neoformans , 1992, The Lancet.

[43]  S. Levitz.  The ecology of Cryptococcus neoformans and the epidemiology of cryptococcosis. , 1991, Reviews of infectious diseases.

[44]  S. A. Meyer,et al.  Facilitated isolation, purification, and analysis of glucuronoxylomannan of Cryptococcus neoformans , 1991, Infection and immunity.

[45]  C. Rinder,et al.  Cryptococcal meningitis and AIDS. , 1988, Annals of emergency medicine.

[46]  M. L. Le Beau,et al.  The CD14 monocyte differentiation antigen maps to a region encoding growth factors and receptors. , 1988, Science.

[47]  R. Eng,et al.  Cryptococcal infections in patients with acquired immune deficiency syndrome. , 1986, The American journal of medicine.

[48]  J. Bennett,et al.  Capsular polysaccharides of Cryptococcus neoformans. , 1984, Reviews of infectious diseases.

[49]  T. Kozel,et al.  The capsule of cryptococcus neoformans passively inhibits phagocytosis of the yeast by macrophages. , 1982, Journal of immunology.

[50]  R. Ulevitch.  Toll gates for pathogen selection , 1999, Nature.

[51]  A. Kakinuma,et al.  Gelation of Limulus amoebocyte lysate by an antitumor (1 leads to 3)-beta-D-glucan. , 1981, Biochemical and biophysical research communications.

[52]  F. Smith,et al.  COLORIMETRIC METHOD FOR DETER-MINATION OF SUGAR AND RELATED SUBSTANCE , 1956 .