Understanding Asthma Phenotypes, Endotypes, and Mechanisms of Disease
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F. E. Lee | M. Kuruvilla | F. Lee | Gerald B. Lee | F. Lee | Gerald Lee
[1] M. Hall. National Heart, Lung, and Blood Institute , 2020, The Grants Register 2021.
[2] E. Bleecker,et al. Refractory airway type 2 inflammation in a large subgroup of asthmatic patients treated with inhaled corticosteroids , 2018, The Journal of allergy and clinical immunology.
[3] P. O'Byrne,et al. Expression of IL-33 and TSLP and Their Receptors in Asthmatic Airways after Inhaled Allergen Challenge. , 2018, American journal of respiratory and critical care medicine.
[4] C. Auffray,et al. Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis , 2018, European Respiratory Journal.
[5] P. Busse,et al. Asthma in the elderly and late‐onset adult asthma , 2018, Allergy.
[6] P. Nair,et al. Airway Inflammation and Inflammatory Biomarkers , 2018, Seminars in Respiratory and Critical Care Medicine.
[7] J. Girard,et al. Interleukin‐33 (IL‐33): A nuclear cytokine from the IL‐1 family , 2018, Immunological reviews.
[8] E. Forno,et al. Obesity and asthma , 2018, The Journal of allergy and clinical immunology.
[9] Stacie M Jones,et al. Individualized Therapy for Persistent Asthma in Young Children , 2017, Pediatrics.
[10] M. Kool,et al. Group 2 Innate Lymphoid Cells Exhibit a Dynamic Phenotype in Allergic Airway Inflammation , 2017, Front. Immunol..
[11] S. Johnston,et al. Viral infections in allergy and immunology: How allergic inflammation influences viral infections and illness , 2017, Journal of Allergy and Clinical Immunology.
[12] P. O'Byrne,et al. Allergen‐induced Increases in Sputum Levels of Group 2 Innate Lymphoid Cells in Subjects with Asthma , 2017, American journal of respiratory and critical care medicine.
[13] M. Profita,et al. Identification of IL‐17F/frequent exacerbator endotype in asthma , 2017, The Journal of allergy and clinical immunology.
[14] S. Wenzel,et al. Severe asthma in humans and mouse model suggests a CXCL10 signature underlies corticosteroid-resistant Th1 bias. , 2017, JCI insight.
[15] W. Busse,et al. Asthma Exacerbations: Pathogenesis, Prevention, and Treatment , 2017, The Journal of Allergy and Clinical Immunology: In Practice.
[16] H. Nakajima,et al. Allergic airway inflammation: key players beyond the Th2 cell pathway , 2017, Immunological reviews.
[17] Frédéric Baribaud,et al. U‐BIOPRED clinical adult asthma clusters linked to a subset of sputum omics , 2017, The Journal of allergy and clinical immunology.
[18] C. Auffray,et al. A Severe Asthma Disease Signature from Gene Expression Profiling of Peripheral Blood from U‐BIOPRED Cohorts , 2017, American journal of respiratory and critical care medicine.
[19] M. D’Amato,et al. Coexistence of obesity and asthma determines a distinct respiratory metabolic phenotype , 2017, The Journal of allergy and clinical immunology.
[20] W. Calhoun,et al. Biologic Therapy in Chronic Obstructive Pulmonary Disease. , 2017, Immunology and allergy clinics of North America.
[21] Stacey N. Reinke,et al. Metabolomics analysis identifies different metabotypes of asthma severity , 2017, European Respiratory Journal.
[22] C. Auffray,et al. A Transcriptome‐driven Analysis of Epithelial Brushings and Bronchial Biopsies to Define Asthma Phenotypes in U‐BIOPRED , 2017, American journal of respiratory and critical care medicine.
[23] Dean P. Jones,et al. High‐resolution metabolomics to identify urine biomarkers in corticosteroid‐resistant asthmatic children , 2017, The Journal of allergy and clinical immunology.
[24] J. Fahy,et al. Claudin‐18 deficiency is associated with airway epithelial barrier dysfunction and asthma , 2017, The Journal of allergy and clinical immunology.
[25] K. Chung,et al. Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study , 2016, Respiratory Research.
[26] M. Cabana,et al. Individualized therapy for persistent asthma in young children. , 2016, The Journal of allergy and clinical immunology.
[27] S. Durham,et al. Omalizumab reduces bronchial mucosal IgE and improves lung function in non-atopic asthma , 2016, European Respiratory Journal.
[28] P. O'Byrne,et al. Measuring Eosinophils to Make Treatment Decisions in Asthma. , 2016, Chest.
[29] M. Kraft,et al. Chronic Infection and Severe Asthma. , 2016, Immunology and allergy clinics of North America.
[30] E. Bleecker,et al. Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts. , 2016, The Lancet. Respiratory medicine.
[31] Miguel Park,et al. Diagnostic Utility of Urinary LTE4 in Asthma, Allergic Rhinitis, Chronic Rhinosinusitis, Nasal Polyps, and Aspirin Sensitivity. , 2016, The journal of allergy and clinical immunology. In practice.
[32] E. Israel,et al. Thymic stromal lymphopoietin controls prostaglandin D2 generation in patients with aspirin-exacerbated respiratory disease. , 2016, The Journal of allergy and clinical immunology.
[33] Francisco Avila Cobos,et al. Asthma inflammatory phenotypes show differential microRNA expression in sputum. , 2016, The Journal of allergy and clinical immunology.
[34] C. Bachert,et al. Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers. , 2016, The Journal of allergy and clinical immunology.
[35] Yusuke Nakamura,et al. Dipeptidyl peptidase-4 is highly expressed in bronchial epithelial cells of untreated asthma and it increases cell proliferation along with fibronectin production in airway constitutive cells , 2016, Respiratory Research.
[36] A. Bhandoola,et al. Group 2 innate lymphoid cells mediate ozone-induced airway inflammation and hyperresponsiveness in mice. , 2016, The Journal of allergy and clinical immunology.
[37] A. Moreira,et al. Volatile organic compounds in asthma diagnosis: a systematic review and meta‐analysis , 2016, Allergy.
[38] K. Samitas,et al. Anti-IgE treatment, airway inflammation and remodelling in severe allergic asthma: current knowledge and future perspectives , 2015, European Respiratory Review.
[39] Y. Kanaoka,et al. Aspirin-Exacerbated Respiratory Disease Involves a Cysteinyl Leukotriene–Driven IL-33–Mediated Mast Cell Activation Pathway , 2015, The Journal of Immunology.
[40] Ioannis Pandis,et al. Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort , 2015, European Respiratory Journal.
[41] D. Postma,et al. Asthma , 2015, Nature Reviews Disease Primers.
[42] S. Wenzel,et al. High IFN-γ and low SLPI mark severe asthma in mice and humans. , 2015, The Journal of clinical investigation.
[43] W. Paul,et al. Innate Immune Function of TH2 Cells in vivo , 2015, Nature Immunology.
[44] C. Sorkness,et al. Markers of Differential Response to Inhaled Corticosteroid Treatment Among Children with Mild Persistent Asthma. , 2015, The journal of allergy and clinical immunology. In practice.
[45] Airway Remodeling in Chronic Obstructive Pulmonary Disease and Asthma: the Role of Matrix Metalloproteinase-9 , 2015, Archivum Immunologiae et Therapiae Experimentalis.
[46] C. Hall,et al. Inflammation, metabolic dysregulation, and pulmonary function among obese urban adolescents with asthma. , 2015, American journal of respiratory and critical care medicine.
[47] R. Lutter,et al. External validation of blood eosinophils, FENO and serum periostin as surrogates for sputum eosinophils in asthma , 2014, Thorax.
[48] W. Jefferies,et al. The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4+ T cells , 2014, Nature Immunology.
[49] Ziv Bar-Joseph,et al. Gene expression in relation to exhaled nitric oxide identifies novel asthma phenotypes with unique biomolecular pathways. , 2014, American journal of respiratory and critical care medicine.
[50] Jonathan R. Brestoff,et al. Basophils Promote Innate Lymphoid Cell Responses in Inflamed Skin , 2014, The Journal of Immunology.
[51] Yongjian Xu,et al. Epithelial interleukin-25 is a key mediator in Th2-high, corticosteroid-responsive asthma. , 2014, American journal of respiratory and critical care medicine.
[52] J. Bousquet,et al. Prevalence of asthma and its association with rhinitis in the elderly. , 2014, Respiratory medicine.
[53] B. Undem,et al. Mechanisms underlying the neuronal-based symptoms of allergy. , 2014, The Journal of allergy and clinical immunology.
[54] Liang Dong,et al. IL-33 promotes airway remodeling and is a marker of asthma disease severity , 2014, The Journal of asthma : official journal of the Association for the Care of Asthma.
[55] J. Balmes,et al. Outdoor air pollution and asthma , 2014, The Lancet.
[56] T. Curtis,et al. Increased expression of bronchial epithelial transient receptor potential vanilloid 1 channels in patients with severe asthma. , 2014, The Journal of allergy and clinical immunology.
[57] P. Woodruff,et al. Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma. , 2014, The Journal of allergy and clinical immunology.
[58] D. Artis,et al. Innate lymphoid cells and allergic inflammation. , 2013, Current opinion in immunology.
[59] L. Rink,et al. The Th17/Treg balance is disturbed during aging , 2013, Experimental Gerontology.
[60] C. Persson. Lysis of primed eosinophils in severe asthma. , 2013, The Journal of allergy and clinical immunology.
[61] J. Marwick,et al. Oxygen levels determine the ability of glucocorticoids to influence neutrophil survival in inflammatory environments , 2013, Journal of leukocyte biology.
[62] S. Phipps,et al. Elevated expression of the NLRP3 inflammasome in neutrophilic asthma , 2013, European Respiratory Journal.
[63] J. Boyce,et al. Lipid mediators and allergic diseases. , 2013, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
[64] E. Bleecker,et al. Biomarker surrogates do not accurately predict sputum eosinophil and neutrophil percentages in asthmatic subjects. , 2013, The Journal of allergy and clinical immunology.
[65] Stacy L. Gelhaus,et al. Prostaglandin D₂ pathway upregulation: relation to asthma severity, control, and TH2 inflammation. , 2013, The Journal of allergy and clinical immunology.
[66] S. Wenzel,et al. Asthma outcomes: biomarkers. , 2012, The Journal of allergy and clinical immunology.
[67] S. Mosesova,et al. Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients. , 2011, The Journal of allergy and clinical immunology.
[68] Lee, Jk,et al. Lebrikizumab treatment in adults with asthma. , 2011 .
[69] Nicola A Hanania,et al. Lebrikizumab treatment in adults with asthma. , 2011, The New England journal of medicine.
[70] W. Busse,et al. What effect does asthma treatment have on airway remodeling? Current perspectives. , 2011, Journal of Allergy and Clinical Immunology.
[71] E. von Mutius,et al. Asthma-associated polymorphisms in 17q21 influence cord blood ORMDL3 and GSDMA gene expression and IL-17 secretion. , 2011, The Journal of allergy and clinical immunology.
[72] W. Busse,et al. Mast cell phenotype, location, and activation in severe asthma. Data from the Severe Asthma Research Program. , 2011, American journal of respiratory and critical care medicine.
[73] J. Bernstein,et al. A novel subset of CD4+ TH2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma , 2010, The Journal of experimental medicine.
[74] Florence Demenais,et al. A large-scale, consortium-based genomewide association study of asthma. , 2010, The New England journal of medicine.
[75] G. Marks,et al. Asthma in older adults , 2010, The Lancet.
[76] Deborah A Meyers,et al. Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes. , 2010, The Journal of allergy and clinical immunology.
[77] E. A. Schwantes,et al. Airway neutrophil inflammatory phenotype in older subjects with asthma. , 2010, The Journal of allergy and clinical immunology.
[78] W. Paul. What determines Th2 differentiation, in vitro and in vivo? , 2010, Immunology and cell biology.
[79] D. Curran‐Everett,et al. Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. , 2010, American journal of respiratory and critical care medicine.
[80] Calman Prussin,et al. IgE, mast cells, basophils, and eosinophils. , 2003, The Journal of allergy and clinical immunology.
[81] Parameswaran Nair,et al. Mepolizumab for prednisone-dependent asthma with sputum eosinophilia. , 2009, The New England journal of medicine.
[82] Qutayba Hamid,et al. Increased Expression of IL-33 in Severe Asthma: Evidence of Expression by Airway Smooth Muscle Cells1 , 2009, The Journal of Immunology.
[83] R. Vennekens,et al. On the putative role of transient receptor potential cation channels in asthma , 2009, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[84] Barmak Modrek,et al. T-helper type 2-driven inflammation defines major subphenotypes of asthma. , 2009, American journal of respiratory and critical care medicine.
[85] C. Lemière,et al. T(H)17-associated cytokines (IL-17A and IL-17F) in severe asthma. , 2009, The Journal of allergy and clinical immunology.
[86] D. Metcalfe,et al. The mast cell and allergic diseases: role in pathogenesis and implications for therapy , 2007, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[87] D. Postma,et al. Down-Regulation of E-Cadherin in Human Bronchial Epithelial Cells Leads to Epidermal Growth Factor Receptor-Dependent Th2 Cell-Promoting Activity1 , 2007, The Journal of Immunology.
[88] H. Renz,et al. Airway epithelial cells produce neurotrophins and promote the survival of eosinophils during allergic airway inflammation. , 2006, The Journal of allergy and clinical immunology.
[89] D. Robinson,et al. Thymic Stromal Lymphopoietin Expression Is Increased in Asthmatic Airways and Correlates with Expression of Th2-Attracting Chemokines and Disease Severity1 , 2005, The Journal of Immunology.
[90] S. Wenzel,et al. Distinguishing severe asthma phenotypes: role of age at onset and eosinophilic inflammation. , 2004, The Journal of allergy and clinical immunology.
[91] J. Oliver,et al. Immunohistochemical detection of human basophils in postmortem cases of fatal asthma. , 2001, American journal of respiratory and critical care medicine.
[92] D. DeMets,et al. Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework , 2001, Clinical pharmacology and therapeutics.
[93] K. Chung,et al. Airway smooth muscle cells: contributing to and regulating airway mucosal inflammation? , 2000, The European respiratory journal.
[94] M. Humbert,et al. Basophils, eosinophils, and mast cells in atopic and nonatopic asthma and in late-phase allergic reactions in the lung and skin. , 2000, The Journal of allergy and clinical immunology.
[95] S. Wenzel,et al. Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics. , 1999, American journal of respiratory and critical care medicine.
[96] M. Brown,et al. Cutting the cord: is birth already too late for primary prevention of allergy? , 1997, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[97] P. Howarth,et al. T-cell cytokine profile evaluated at the single cell level in BAL and blood in allergic asthma. , 1996, American journal of respiratory cell and molecular biology.
[98] M. Lebowitz,et al. The relationship between parental and children's serum IgE and asthma. , 1995, American journal of respiratory and critical care medicine.