Generation of Aurachin Derivatives by Whole-Cell Biotransformation and Evaluation of Their Antiprotozoal Properties
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S. Lütz | M. Nett | M. Kaiser | Sebastian Kruth | Wolf Hiller | J. Pietruszka | Cindy J.-M. Zimmermann | Katharina Kuhr
[1] M. Nett,et al. Biocatalytic production of the antibiotic aurachin D in Escherichia coli , 2022, AMB Express.
[2] A. Gamble,et al. Synthesis and Biological Evaluation of Aurachin D Analogues as Inhibitors of Mycobacterium tuberculosis Cytochrome bd Oxidase. , 2022, ACS medicinal chemistry letters.
[3] R. Weis,et al. Antiprotozoal Activity of Azabicyclo-Nonanes Linked to Tetrazole or Sulfonamide Cores , 2022, Molecules.
[4] M. Nett,et al. Emerging concepts in the semisynthetic and mutasynthetic production of natural products. , 2022, Current opinion in biotechnology.
[5] Kuljit Singh,et al. Virulence factors of Leishmania parasite: Their paramount importance in unraveling novel vaccine candidates and therapeutic targets. , 2022, Life sciences.
[6] S. Peter,et al. High Plasticity of the Amicetin Biosynthetic Pathway in Streptomyces sp. SHP 22-7 Led to the Discovery of Streptcytosine P and Cytosaminomycins F and G and Facilitated the Production of 12F-Plicacetin. , 2022, Journal of natural products.
[7] H. Schwalbe,et al. Short-chain aurachin D derivatives are selective inhibitors of E. coli cytochrome bd-I and bd-II oxidases , 2021, Scientific Reports.
[8] J. Pietruszka,et al. Mutasynthesis of Physostigmines in Myxococcus xanthus. , 2021, Organic letters.
[9] D. Adpressa,et al. Precursor-Directed Biosynthesis of Aminofulvenes: New Chalanilines from Endophytic Fungus Chalara sp. , 2021, Molecules.
[10] C. R. Alves,et al. Axenic amastigotes of Leishmania species as a suitable model for in vitro studies. , 2021, Acta tropica.
[11] Atukuri Dorababu. Quinoline: A Promising Scaffold in Recent Antiprotozoal Drug Discovery , 2021, ChemistrySelect.
[12] Rachel Tidman,et al. The impact of climate change on neglected tropical diseases: a systematic review , 2021, Transactions of the Royal Society of Tropical Medicine and Hygiene.
[13] M. Nett,et al. Bioengineering of Anti‐Inflammatory Natural Products , 2020, ChemMedChem.
[14] P. Mäser,et al. HPLC-Based Activity Profiling for Antiprotozoal Compounds in Croton gratissimus and Cuscuta hyalina , 2020, Frontiers in Pharmacology.
[15] Manish Walia,et al. Synthesis of (-)-Melodinine K: A Case Study of Efficiency in Natural Product Synthesis. , 2020, Journal of natural products.
[16] S. Lütz,et al. Biosynthetic Plasticity Enables Production of Fluorinated Aurachins , 2020, Chembiochem : a European journal of chemical biology.
[17] David J Newman,et al. Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019. , 2020, Journal of natural products.
[18] L. Bavia,et al. Chagas Disease: From Discovery to a Worldwide Health Problem , 2019, Front. Public Health.
[19] A. Vcev,et al. Malaria: The Past and the Present , 2019, Microorganisms.
[20] Greta Volpedo,et al. Host-Directed Drug Therapies for Neglected Tropical Diseases Caused by Protozoan Parasites , 2018, Front. Microbiol..
[21] D. Molyneux,et al. Neglected tropical diseases: progress towards addressing the chronic pandemic , 2017, The Lancet.
[22] Robert H Bates,et al. Searching for New Leads for Tuberculosis: Design, Synthesis, and Biological Evaluation of Novel 2-Quinolin-4-yloxyacetamides. , 2016, Journal of medicinal chemistry.
[23] A. Saxena,et al. Novel, potent, orally bioavailable and selective mycobacterial ATP synthase inhibitors that demonstrated activity against both replicating and non-replicating M. tuberculosis. , 2015, Bioorganic & medicinal chemistry.
[24] P. Simarro,et al. Epidemiology of human African trypanosomiasis , 2014, Clinical epidemiology.
[25] K. Andrews,et al. Drug repurposing and human parasitic protozoan diseases , 2014, International journal for parasitology. Drugs and drug resistance.
[26] A. Speicher,et al. Synthesis of aurachin D and isoprenoid analogues from the myxobacterium Stigmatella aurantiaca , 2013 .
[27] R. Müller,et al. Synthesis and biological activities of the respiratory chain inhibitor aurachin D and new ring versus chain analogues , 2013, Beilstein journal of organic chemistry.
[28] Jay D. Keasling,et al. Identification and microbial production of a terpene-based advanced biofuel , 2011, Nature communications.
[29] R. Müller,et al. AuaA, a Membrane‐Bound Farnesyltransferase from Stigmatella aurantiaca, Catalyzes the Prenylation of 2‐Methyl‐4‐hydroxyquinoline in the Biosynthesis of Aurachins , 2011, Chembiochem : a European journal of chemical biology.
[30] Umberto D'Alessandro,et al. Quinine, an old anti-malarial drug in a modern world: role in the treatment of malaria , 2011, Malaria Journal.
[31] R. Müller,et al. Completing the puzzle of aurachin biosynthesis in Stigmatella aurantiaca Sg a15. , 2011, Molecular bioSystems.
[32] Roman Manetsch,et al. Divergent route to access structurally diverse 4-quinolones via mono or sequential cross-couplings. , 2010, The Journal of organic chemistry.
[33] Hemantkumar S. Deokar,et al. Novel quinoline and naphthalene derivatives as potent antimycobacterial agents. , 2010, European journal of medicinal chemistry.
[34] Q. You,et al. Microwave-Assisted Simple Synthesis of Substituted 4-Quinolone Derivatives , 2009 .
[35] B. Kunze,et al. Semisynthesis and antiplasmodial activity of the quinoline alkaloid aurachin E. , 2008, Journal of natural products.
[36] R. Kaminsky,et al. The Alamar Blue assay to determine drug sensitivity of African trypanosomes (T.b. rhodesiense and T.b. gambiense) in vitro. , 1997, Acta tropica.
[37] F. Buckner,et al. Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase , 1996, Antimicrobial agents and chemotherapy.
[38] P. Rich,et al. New inhibitors of the quinol oxidation sites of bacterial cytochromes bo and bd. , 1995, Biochemistry.
[39] H. Reichenbach,et al. The aurachins, new quinoline antibiotics from myxobacteria: production, physico-chemical and biological properties. , 1987, The Journal of antibiotics.
[40] I. Cunningham. New culture medium for maintenance of tsetse tissues and growth of trypanosomatids. , 1977, The Journal of protozoology.