Rheological effects of hypertonic saline and sodium bicarbonate solutions on cystic fibrosis sputum in vitro

[1]  M. Steward,et al.  Antibacterial Effects of Bicarbonate in Media Modified to Mimic Cystic Fibrosis Sputum , 2020, International journal of molecular sciences.

[2]  C. Murray,et al.  Inhaled mannitol for cystic fibrosis. , 2020, The Cochrane database of systematic reviews.

[3]  J. Cavanaugh,et al.  Randomized controlled study of aerosolized hypertonic xylitol versus hypertonic saline in hospitalized patients with pulmonary exacerbation of cystic fibrosis. , 2020, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

[4]  P. Quinton,et al.  Safety, Tolerability, and Effects of Sodium Bicarbonate Inhalation in Cystic Fibrosis , 2019, Clinical Drug Investigation.

[5]  R. Tarran,et al.  Pathological mucus and impaired mucus clearance in cystic fibrosis patients result from increased concentration, not altered pH , 2018, European Respiratory Journal.

[6]  P. Quinton,et al.  Bicarbonate Inhibits Bacterial Growth and Biofilm Formation of Prevalent Cystic Fibrosis Pathogens , 2018, Front. Microbiol..

[7]  L. Kang,et al.  Cystic Fibrosis Sputum Rheology Correlates With Both Acute and Longitudinal Changes in Lung Function , 2018, Chest.

[8]  C. Benden,et al.  The many ways sputum flows – Dealing with high within-subject variability in cystic fibrosis sputum rheology , 2018, Respiratory Physiology & Neurobiology.

[9]  P. Russo,et al.  Rheological Properties of Cystic Fibrosis Bronchial Secretion and in Vitro Drug Permeation Study: The Effect of Sodium Bicarbonate. , 2016, Journal of aerosol medicine and pulmonary drug delivery.

[10]  R. Sadikot Exacerbations of Cystic Fibrosis , 2016 .

[11]  B. Antus Oxidative Stress Markers in Sputum , 2016, Oxidative medicine and cellular longevity.

[12]  Tiffany J Dwyer,et al.  Inhaled mannitol for cystic fibrosis. , 2015, The Cochrane database of systematic reviews.

[13]  Garry R. Cutting,et al.  Cystic fibrosis genetics: from molecular understanding to clinical application , 2014, Nature Reviews Genetics.

[14]  S. Donaldson,et al.  Hypertonic saline for cystic fibrosis: worth its salt? , 2014, Expert review of respiratory medicine.

[15]  P. Quinton,et al.  Normal mucus formation requires cAMP‐dependent HCO3− secretion and Ca2+‐mediated mucin exocytosis , 2013, The Journal of physiology.

[16]  R. Cone,et al.  Barrier properties of mucus. , 2009, Advanced drug delivery reviews.

[17]  P. Quinton Cystic fibrosis: impaired bicarbonate secretion and mucoviscidosis , 2008, The Lancet.

[18]  I. Doull,et al.  Hypertonic saline inhalation in cystic fibrosis—salt in the wound, or sweet success? , 2007, Archives of Disease in Childhood.

[19]  R. Kuhn,et al.  Hypertonic Saline Treatment of Cystic Fibrosis , 2007, The Annals of pharmacotherapy.

[20]  B. Rubin Mucus structure and properties in cystic fibrosis. , 2007, Paediatric respiratory reviews.

[21]  C. Goss,et al.  Exacerbations in cystic fibrosis · 1: Epidemiology and pathogenesis , 2007, Thorax.

[22]  S. Anderson,et al.  Hyperosmolar agents and clearance of mucus in the diseased airway. , 2006, Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine.

[23]  Mark R Elkins,et al.  A controlled trial of long-term inhaled hypertonic saline in patients with cystic fibrosis. , 2006, The New England journal of medicine.

[24]  M. King,et al.  A new paradigm in respiratory hygiene: increasing the cohesivity of airway secretions to improve cough interaction and reduce aerosol dispersion , 2005, BMC pulmonary medicine.

[25]  S. Anderson,et al.  Inhaled mannitol for the treatment of mucociliary dysfunction in patients with bronchiectasis: Effect on lung function, health status and sputum , 2005, Respirology.

[26]  B. Rubin A superficial view of mucus and the cystic fibrosis defect , 1992, Pediatric pulmonology.

[27]  J. Zahm,et al.  Phospholipid composition and surface‐active properties of tracheobronchial secretions from patients with cystic fibrosis and chronic obstructive pulmonary diseases , 1992, Pediatric pulmonology.

[28]  J. Zahm,et al.  Rheology of sputum collected by a simple technique limiting salivary contamination. , 1984, The Journal of laboratory and clinical medicine.

[29]  J. Kline,et al.  Safety assessment of inhaled xylitol in subjects with cystic fibrosis. , 2007, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

[30]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[31]  M. King The role of mucus viscoelasticity in cough clearance. , 1987, Biorheology.