Blood Changes and Diagnosis of Infectious Mononucleosis

positioned. Failure is only likely when the saphena is duplicated. Making the probe elastic, as Murphy suggests, would help, especially when it is passed from below upwards, as the late Sir Henry Gray, who introduced the method into Britain, often did. The results of extraction were excellent in 20 soldiers traced five years after operation (Brit. J. Surg., 1921, 8, 486), but subsequent experience has shown that they are perhaps not so good in civilians. The danger of deep thrombosis being caused by overflow into the deep veins, given as a possible reason for the newer method, must be rare in the absence of previous white leg, in which case any treatment other than Unna's semi-rigid method, used hydrostatically over a long period, seems to be contraindicated. The use of the larger salicylate and other injections, which often produoed severe cellulitis, is largely in abeyance. The smaller quinine injection seems to carry no such risk, as the deep vein dilution is large and sudden, and the results are uniform and very good. A disadvantage is that the solution is not guidable by the pain it produces. It was shown (British Medical Journal, 1929, 2, 848) that solutions which produced delayed pain after injection could be easily guided into any desired area affected with varicosity. Until someone with suitable material adjusts the percentage of urethane so as to produce only slight pain on injection we shall have to continue with the more haphazard method and hope that previous ligatures will not direct too large a quantity of the solution into the deep veins.-I am, etc.,