NOTCH and PI3K-AKT pathways intertwined.
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A. Look | A. Gutierrez | A. Look | A. T. Look
[1] Govind Bhagat,et al. Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia , 2007, Nature Medicine.
[2] G. Mills,et al. A new mutational AKTivation in the PI3K pathway. , 2007, Cancer cell.
[3] Rob Pieters,et al. FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors , 2007, The Journal of experimental medicine.
[4] A. Ferrando,et al. The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia , 2007, The Journal of experimental medicine.
[5] R. Tibshirani,et al. Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia. , 2007, Blood.
[6] Adam A. Margolin,et al. NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth , 2006, Proceedings of the National Academy of Sciences.
[7] M. Bhasin,et al. Notch1 Contributes to Mouse T-Cell Leukemia by Directly Inducing the Expression of c-myc , 2006, Molecular and Cellular Biology.
[8] J. Aster,et al. c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma. , 2006, Genes & development.
[9] A. Look,et al. Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia , 2006, Nature Reviews Cancer.
[10] Yiling Lu,et al. Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery , 2005, Nature Reviews Drug Discovery.
[11] C. Arvanitis,et al. Conditionally MYC: insights from novel transgenic models. , 2005, Cancer letters.
[12] Andrew P. Weng,et al. Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia , 2004, Science.