Activin signals via SMAD2/3 between germ and somatic cells in the human fetal ovary and regulates kit ligand expression.

[1]  B. Vanderhyden,et al.  Kit Ligand 2 Promotes Murine Oocyte Growth In Vitro1 , 2008, Biology of reproduction.

[2]  Martin M Matzuk,et al.  Intraovarian activins are required for female fertility. , 2007, Molecular endocrinology.

[3]  R. Anderson,et al.  Seminal plasma and prostaglandin E2 up-regulate fibroblast growth factor 2 expression in endometrial adenocarcinoma cells via E-series prostanoid-2 receptor-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase pathway. , 2007, Human reproduction.

[4]  L. Shea,et al.  Postnatal regulation of germ cells by activin: the establishment of the initial follicle pool. , 2006, Developmental biology.

[5]  Phil G Knight,et al.  TGF-beta superfamily members and ovarian follicle development. , 2006, Reproduction.

[6]  L. Reber,et al.  Stem cell factor and its receptor c-Kit as targets for inflammatory diseases. , 2006, European journal of pharmacology.

[7]  E. McLaughlin,et al.  Kit ligand and c-Kit have diverse roles during mammalian oogenesis and folliculogenesis. , 2006, Molecular human reproduction.

[8]  M. Costa,et al.  Loss of synaptonemal complex protein-1, a synaptonemal complex protein, contributes to the initiation of follicular assembly in the developing rat ovary. , 2005, Endocrinology.

[9]  M. Skinner.  Regulation of primordial follicle assembly and development. , 2005, Human reproduction update.

[10]  R. Anderson,et al.  Germ cell proliferation and apoptosis in the developing human ovary. , 2005, The Journal of clinical endocrinology and metabolism.

[11]  K. Møllgård,et al.  Stem cell factor and c-Kit in human primordial germ cells and fetal ovaries , 2005, Molecular and Cellular Endocrinology.

[12]  J. Flaws,et al.  Ovarian follicle development requires Smad3. , 2004, Molecular endocrinology.

[13]  Martin M Matzuk,et al.  NOBOX Deficiency Disrupts Early Folliculogenesis and Oocyte-Specific Gene Expression , 2004, Science.

[14]  R. Bayne,et al.  Increased expression of the FIGLA transcription factor is associated with primordial follicle formation in the human fetal ovary. , 2004, Molecular human reproduction.

[15]  N. Zachos,et al.  Localization and Developmental Expression of the Activin Signal Transduction Proteins Smads 2, 3, and 4 in the Baboon Fetal Ovary1 , 2004, Biology of reproduction.

[16]  R. Anderson,et al.  Expression of activin subunits and receptors in the developing human ovary: activin A promotes germ cell survival and proliferation before primordial follicle formation. , 2004, Developmental biology.

[17]  M. Skinner,et al.  Kit ligand and basic fibroblast growth factor interactions in the induction of ovarian primordial to primary follicle transition , 2004, Molecular and Cellular Endocrinology.

[18]  F. Otsuka,et al.  The bone morphogenetic protein system in mammalian reproduction. , 2004, Endocrine reviews.

[19]  D. Price,et al.  The role of neurotrophin receptors in female germ-cell survival in mouse and human , 2003, Development.

[20]  P. G. Knight,et al.  Local roles of TGF-beta superfamily members in the control of ovarian follicle development. , 2003, Animal reproduction science.

[21]  K. Kuchler,et al.  Activin A Signaling Induces Smad2, but Not Smad3, Requiring Protein Kinase A Activity in Granulosa Cells from the Avian Ovary* , 2003, Journal of Biological Chemistry.

[22]  J. Findlay,et al.  Ovarian follicle populations of the rat express TGF-β signalling pathways , 2003, Molecular and Cellular Endocrinology.

[23]  P. Leung,et al.  Activin-A up-regulates type I activin receptor mRNA levels in human immortalized extravillous trophoblast cells. , 2003, Reproductive biology and endocrinology : RB&E.

[24]  J. Findlay,et al.  Ovarian follicle populations of the rat express TGF-beta signalling pathways. , 2003, Molecular and cellular endocrinology.

[25]  M. Matzuk,et al.  Genetic Analysis of the Mammalian Transforming Growth Factor-β Superfamily , 2002 .

[26]  J. Dean,et al.  Mouse genetics provides insight into folliculogenesis, fertilization and early embryonic development. , 2002, Human reproduction update.

[27]  R. Anderson,et al.  Developmental changes in expression of myeloid cell leukemia-1 in human germ cells during oogenesis and early folliculogenesis. , 2002, The Journal of clinical endocrinology and metabolism.

[28]  D. Robertson,et al.  Recruitment and development of the follicle; the roles of the transforming growth factor-β superfamily , 2002, Molecular and Cellular Endocrinology.

[29]  J. Juengel,et al.  Formation of Ovarian Follicles During Fetal Development in Sheep1 , 2002, Biology of reproduction.

[30]  M. De Felici,et al.  In vitro development of growing oocytes from fetal mouse oocytes: stage-specific regulation by stem cell factor and granulosa cells. , 2002, Developmental biology.

[31]  C. Deng,et al.  Smad 3 May Regulate Follicular Growth in the Mouse Ovary1 , 2002, Biology of reproduction.

[32]  N. Spears,et al.  Neurotropins and their receptors are expressed in the human fetal ovary. , 2002, The Journal of clinical endocrinology and metabolism.

[33]  J. Dean,et al.  Oocyte-specific genes regulate follicle formation, fertility and early mouse development. , 2002, Journal of reproductive immunology.

[34]  M. Matzuk,et al.  Genetic analysis of the mammalian transforming growth factor-beta superfamily. , 2002, Endocrine reviews.

[35]  J. Juengel,et al.  Genetic mutations influencing ovulation rate in sheep. , 2001, Reproduction, fertility, and development.

[36]  P. Saunders,et al.  Germ cell specific expression of c-kit in the human fetal gonad. , 2001, Molecular human reproduction.

[37]  R. W. Padgett,et al.  New Developments for TGF , 2001 .

[38]  T. Vaskivuo,et al.  Survival of human ovarian follicles from fetal to adult life: apoptosis, apoptosis-related proteins, and transcription factor GATA-4. , 2001, The Journal of clinical endocrinology and metabolism.

[39]  A. Spradling,et al.  Mouse ovarian germ cell cysts undergo programmed breakdown to form primordial follicles. , 2001, Developmental biology.

[40]  M. Skinner,et al.  Basic fibroblast growth factor induces primordial follicle development and initiates folliculogenesis , 2001, Molecular and Cellular Endocrinology.

[41]  J. Richards.  Perspective: the ovarian follicle--a perspective in 2001. , 2001, Endocrinology.

[42]  R. W. Padgett,et al.  New developments for TGFbeta. , 2001, Developmental cell.

[43]  R. Cortvrindt,et al.  Roles of KIT and KIT LIGAND in ovarian function. , 2000, Reviews of reproduction.

[44]  M. Matzuk,et al.  Insertion of Inhbb into the Inhba locus rescues the Inhba-null phenotype and reveals new activin functions , 2000, Nature Genetics.

[45]  Steve D. M. Brown,et al.  A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse , 2000, Nature Genetics.

[46]  S. Ojeda,et al.  Neurotrophic and cell–cell dependent control of early follicular development , 2000, Molecular and Cellular Endocrinology.

[47]  M. Matzuk.  Revelations of ovarian follicle biology from gene knockout mice , 2000, Molecular and Cellular Endocrinology.

[48]  M. Matzuk,et al.  Oocyte-expressed TGF-β superfamily members in female fertility , 2000, Molecular and Cellular Endocrinology.

[49]  E. Lehtonen,et al.  Localization of growth differentiation factor-9 (GDF-9) mRNA and protein in rat ovaries and cDNA cloning of rat GDF-9 and its novel homolog GDF-9B , 1999, Molecular and Cellular Endocrinology.

[50]  A. Bradley,et al.  Multiple roles for activin-like kinase-2 signaling during mouse embryogenesis. , 1999, Developmental biology.

[51]  J. Yeh,et al.  Expression of transforming growth factor (TGF)-β1, TGF-β2, and TGF-β3 and of type I and II TGF-β receptors during the development of the human fetal ovary☆ , 1999 .

[52]  C. Clay,et al.  Molecular cloning of the ovine Growth/Differentiation factor-9 gene and expression of growth/differentiation factor-9 in ovine and bovine ovaries. , 1999, Biology of reproduction.

[53]  J. Yeh,et al.  Expression of transforming growth factor (TGF)-beta1, TGF-beta2, and TGF-beta3 and of type I and II TGF-beta receptors during the development of the human fetal ovary. , 1999, Fertility and sterility.

[54]  J. Graff,et al.  Smad3 Mutant Mice Develop Metastatic Colorectal Cancer , 1998, Cell.

[55]  J. Massagué.  TGF-beta signal transduction. , 1998, Annual review of biochemistry.

[56]  A. Forabosco,et al.  Apoptosis of germ cells during human prenatal oogenesis. , 1997, Human reproduction.

[57]  B. Vanderhyden,et al.  Hormonally regulated expression and alternative splicing of kit ligand may regulate kit-induced inhibition of meiosis in rat oocytes. , 1997, Developmental biology.

[58]  B. Vanderhyden,et al.  Hormonal regulation of the ligand for c‐kit in the rat ovary and its effects on spontaneous oocyte meiotic maturation , 1996, Molecular reproduction and development.

[59]  S. Ojeda,et al.  Expression of neurotrophins and their receptors in the mammalian ovary is developmentally regulated: changes at the time of folliculogenesis. , 1995, Endocrinology.

[60]  A. Bradley,et al.  Different phenotypes for mice deficient in either activins or activin receptor type II , 1995, Nature.

[61]  S. McGrath,et al.  Oocyte-specific expression of growth/differentiation factor-9. , 1995, Molecular endocrinology.

[62]  W. Crowley,et al.  Characterization of unique binding kinetics of follistatin and activin or inhibin in serum. , 1994, Endocrinology.

[63]  R. Jaenisch,et al.  Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction. , 1994, Genes & development.

[64]  E. Huang,et al.  The expression pattern of the c-kit ligand in gonads of mice supports a role for the c-kit receptor in oocyte growth and in proliferation of spermatogonia. , 1993, Developmental biology.

[65]  A N Hirshfield,et al.  Development of follicles in the mammalian ovary. , 1991, International review of cytology.

[66]  K. Titani,et al.  Activin-binding protein from rat ovary is follistatin. , 1990, Science.

[67]  T. G. Baker,et al.  A QUANTITATIVE AND CYTOLOGICAL STUDY OF GERM CELLS IN HUMAN OVARIES. , 1964, Proceedings of the Royal Society of London. Series B, Biological sciences.