Background Since 1982, cancer has been the highest among the top ten causes of death among Chinese people. In particular, patients undergoing chemotherapy need to face the physiological effects of chemotherapy side effects, and also need to adapt to the changes and impacts of the quality of life caused by the disease itself and treatment. Therefore, a detailed assessment of the physiological and psychological symptoms caused by chemotherapy in patients, through music therapy, to evaluate whether it can reduce or prevent the anxiety level of cancer patients during chemotherapy. In turn, the patient can continue to receive chemotherapy, which is the goal that clinical nurses can work hard. Methods We used a randomized, parallel-group, controlled trial design and allocated the 60 enrolled participants. Randomly assigned to the experimental group and the control group, each group of 30. The experimental group listened to the MP3 player with headphones for 30 minutes of optional music during chemotherapy. The control group listened to the MP3 player for 30 minutes of ambient sound during the chemotherapy period. Subjects were tested for anxiety, salivary amylase, and finger temperature before, 6th, 12th, and 24th week of interventional measures.
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