Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma.
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O. van Tellingen | M. van Lohuizen | S. Bruggeman | J. Zevenhoven | E. Tanger | D. Hulsman | T. Buckle | M. Blom | Ellen Tanger
[1] S. Mörk,et al. Giant cell glioblastoma and pleomorphic xanthoastrocytoma. , 2009, Archives of pathology & laboratory medicine.
[2] B. Scheithauer,et al. The 2007 WHO Classification of Tumours of the Central Nervous System , 2007, Acta Neuropathologica.
[3] Irving L Weissman,et al. Bmi‐1‐Green Fluorescent Protein‐Knock‐In Mice Reveal the Dynamic Regulation of Bmi‐1 Expression in Normal and Leukemic Hematopoietic Cells , 2007, Stem cells.
[4] Hongjuan Cui,et al. Bmi-1 is essential for the tumorigenicity of neuroblastoma cells. , 2007, The American journal of pathology.
[5] I. Weissman,et al. Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma , 2007, Proceedings of the National Academy of Sciences.
[6] A Heerschap,et al. Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studies. , 2006, European journal of cancer.
[7] J. Massagué,et al. Cancer Metastasis: Building a Framework , 2006, Cell.
[8] H. Ding,et al. Bmi-1 Regulates the Differentiation and Clonogenic Self-renewal of I-type Neuroblastoma Cells in a Concentration-dependent Manner* , 2006, Journal of Biological Chemistry.
[9] Eric C. Holland,et al. Mouse Models of Brain Tumors and Their Applications in Preclinical Trials , 2006, Clinical Cancer Research.
[10] L. Liu,et al. Loss of the human polycomb group protein BMI1 promotes cancer-specific cell death , 2006, Oncogene.
[11] J. Zeitlinger,et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells , 2006, Nature.
[12] Kristian Helin,et al. Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. , 2006, Genes & development.
[13] Megan F. Cole,et al. Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells , 2006, Cell.
[14] Michel Bellis,et al. Chromosomal Distribution of PcG Proteins during Drosophila Development , 2006, PLoS biology.
[15] B. Steensel,et al. Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster , 2006, Nature Genetics.
[16] M. Sofroniew,et al. Phenotypic and functional heterogeneity of GFAP‐expressing cells in vitro: Differential expression of LeX/CD15 by GFAP‐expressing multipotent neural stem cells and non‐neurogenic astrocytes , 2006, Glia.
[17] Mitchel S Berger,et al. Neural stem cells and the origin of gliomas. , 2005, The New England journal of medicine.
[18] Austin G Smith,et al. Niche-Independent Symmetrical Self-Renewal of a Mammalian Tissue Stem Cell , 2005, PLoS biology.
[19] Dawen Zhao,et al. Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma. , 2005, Cancer cell.
[20] Y. Arsenijévic,et al. Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice. , 2005, Genes & development.
[21] C. Kostic,et al. Bmi1 Loss Produces an Increase in Astroglial Cells and a Decrease in Neural Stem Cell Population and Proliferation , 2005, The Journal of Neuroscience.
[22] S. Morrison,et al. Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways. , 2005, Genes & development.
[23] Christoph Wülfing,et al. Polycomb Group Protein Ezh2 Controls Actin Polymerization and Cell Signaling , 2005, Cell.
[24] R. Henkelman,et al. Identification of human brain tumour initiating cells , 2004, Nature.
[25] Lu‐Hai Wang. Molecular signaling regulating anchorage-independent growth of cancer cells. , 2004, The Mount Sinai journal of medicine, New York.
[26] M. Sofroniew,et al. GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain , 2004, Nature Neuroscience.
[27] Ugo Orfanelli,et al. Isolation and Characterization of Tumorigenic, Stem-like Neural Precursors from Human Glioblastoma , 2004, Cancer Research.
[28] M. Lohuizen,et al. Stem Cells and Cancer The Polycomb Connection , 2004, Cell.
[29] R. Weinberg,et al. Species- and cell type-specific requirements for cellular transformation. , 2004, Cancer cell.
[30] M. Lohuizen,et al. Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas , 2004, Nature.
[31] Daniel H. Geschwind,et al. Cancerous stem cells can arise from pediatric brain tumors , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[32] S. Morrison,et al. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation , 2003, Nature.
[33] S. Powell,et al. Giant cell glioblastoma and pleomorphic xanthoastrocytoma show different immunohistochemical profiles for neuronal antigens and p53 but share reactivity for class III beta-tubulin. , 2003, Archives of pathology & laboratory medicine.
[34] G. Sauvageau,et al. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells , 2003, Nature.
[35] Irving L. Weissman,et al. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells , 2003, Nature.
[36] M. Westphal,et al. Cost of migration: invasion of malignant gliomas and implications for treatment. , 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[37] M. Sofroniew,et al. The Predominant Neural Stem Cell Isolated from Postnatal and Adult Forebrain But Not Early Embryonic Forebrain Expresses GFAP , 2003, The Journal of Neuroscience.
[38] S. Morrison,et al. Prospective identification of tumorigenic breast cancer cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[39] L. Parada,et al. The Molecular and Genetic Basis of Neurological Tumours , 2002, Nature Reviews Cancer.
[40] R. DePinho,et al. Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. , 2002, Cancer cell.
[41] G. Reifenberger,et al. The WHO Classification of Tumors of the Nervous System , 2002, Journal of neuropathology and experimental neurology.
[42] A. Frankfurter,et al. Aberrant Localization of the Neuronal Class III b-Tubulin in Astrocytomas A Marker for Anaplastic Potential , 2001 .
[43] D. Steindler,et al. Identification of a multipotent astrocytic stem cell in the immature and adult mouse brain. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[44] Daniel A. Lim,et al. Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult Mammalian Brain , 1999, Cell.
[45] K Kornfeld,et al. Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase. , 1999, Genes & development.
[46] H. Varmus,et al. A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice. , 1998, Genes & development.
[47] J. Dick,et al. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell , 1997, Nature Medicine.
[48] P. Warne,et al. Role of Phosphoinositide 3-OH Kinase in Cell Transformation and Control of the Actin Cytoskeleton by Ras , 1997, Cell.
[49] L. Chin,et al. Role of the INK4a Locus in Tumor Suppression and Cell Mortality , 1996, Cell.
[50] W. Cavenee,et al. A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[51] M. Sofroniew,et al. Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene. , 1994, Genes & development.
[52] M. Caligiuri,et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice , 1994, Nature.
[53] C. James,et al. Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[54] Anton Berns,et al. Identification of cooperating oncogenes in Eμ-myc transgenic mice by provirus tagging , 1991, Cell.
[55] W. Alexander,et al. Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in Eμ-myc transgenic mice , 1991, Cell.
[56] K. McCarthy,et al. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue , 1980, The Journal of cell biology.
[57] V. Freedman,et al. Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium. , 1974, Cell.
[58] John Quackenbush,et al. Genesis: cluster analysis of microarray data , 2002, Bioinform..