Physiology-Based Kinetic Modeling of Neuronal Energy Metabolism Unravels the Molecular Basis of NAD(P)H Fluorescence Transients
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Hermann-Georg Holzhütter | Nikolaus Berndt | H. Holzhütter | O. Kann | Nikolaus Berndt | Oliver Kann
[1] S. Bulik,et al. Implications of enzyme deficiencies on mitochondrial energy metabolism and reactive oxygen species formation of neurons involved in rotenone‐induced Parkinson's disease: a model‐based analysis , 2013, The FEBS journal.
[2] H. Holzhütter,et al. Oxygen Consumption Rates during Three Different Neuronal Activity States in the Hippocampal CA3 Network , 2013, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[3] David A. Boas,et al. In vivo imaging of cerebral energy metabolism with two-photon fluorescence lifetime microscopy of NADH , 2013, Biomedical optics express.
[4] G. Dienel,et al. Brain Lactate Metabolism: The Discoveries and the Controversies , 2012, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[5] David Attwell,et al. Oxidative Phosphorylation, Not Glycolysis, Powers Presynaptic and Postsynaptic Mechanisms Underlying Brain Information Processing , 2012, The Journal of Neuroscience.
[6] S. Bulik,et al. Kinetic Modeling of the Mitochondrial Energy Metabolism of Neuronal Cells: The Impact of Reduced α-Ketoglutarate Dehydrogenase Activities on ATP Production and Generation of Reactive Oxygen Species , 2012, International journal of cell biology.
[7] R. Llinás,et al. Cytosolic Calcium Coordinates Mitochondrial Energy Metabolism with Presynaptic Activity , 2012, The Journal of Neuroscience.
[8] C. Mathiesen,et al. Activity-dependent Increases in Local Oxygen Consumption Correlate with Postsynaptic Currents in the Mouse Cerebellum In Vivo , 2011, The Journal of Neuroscience.
[9] C. Ayata,et al. Two-photon microscopy of cortical NADH fluorescence intensity changes: correcting contamination from the hemodynamic response. , 2011, Journal of biomedical optics.
[10] H. Holzhütter,et al. The influence of the chloride currents on action potential firing and volume regulation of excitable cells studied by a kinetic model. , 2011, Journal of theoretical biology.
[11] G. Somjen,et al. Simultaneous Monitoring of Tissue Po2 and NADH Fluorescence During Synaptic Stimulation and Spreading Depression Reveals a Transient Dissociation between Oxygen Utilization and Mitochondrial Redox State in Rat Hippocampal Slices , 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[12] J. Rillich,et al. The biphasic NAD(P)H fluorescence response of astrocytes to dopamine reflects the metabolic actions of oxidative phosphorylation and glycolysis , 2010, Journal of neurochemistry.
[13] C. Shuttleworth,et al. Use of NAD(P)H and flavoprotein autofluorescence transients to probe neuron and astrocyte responses to synaptic activation , 2010, Neurochemistry International.
[14] N. Secher,et al. Lactate fuels the human brain during exercise , 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[15] T. Videen,et al. Cerebral Mitochondrial Metabolism in Early Parkinson's Disease , 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[16] Jakub Otáhal,et al. Gamma Oscillations and Spontaneous Network Activity in the Hippocampus Are Highly Sensitive to Decreases in pO2 and Concomitant Changes in Mitochondrial Redox State , 2008, The Journal of Neuroscience.
[17] D. Turner,et al. Lactate uptake contributes to the NAD(P)H biphasic response and tissue oxygen response during synaptic stimulation in area CA1 of rat hippocampal slices , 2007, Journal of neurochemistry.
[18] Britton Chance,et al. Oxidation-reduction states of NADH in vivo: from animals to clinical use. , 2007, Mitochondrion.
[19] P. Magistretti,et al. Activity‐dependent regulation of energy metabolism by astrocytes: An update , 2007, Glia.
[20] P. Magistretti,et al. A coherent neurobiological framework for functional neuroimaging provided by a model integrating compartmentalized energy metabolism , 2007, Proceedings of the National Academy of Sciences.
[21] Avraham Mayevsky,et al. Mitochondrial function in vivo evaluated by NADH fluorescence: from animal models to human studies. , 2007 .
[22] S. Thayer,et al. Mitochondrial modulation of Ca2+ -induced Ca2+ -release in rat sensory neurons. , 2006, Journal of neurophysiology.
[23] Arne Schousboe,et al. Neuronal and astrocytic shuttle mechanisms for cytosolic-mitochondrial transfer of reducing equivalents: current evidence and pharmacological tools. , 2006, Biochemical pharmacology.
[24] B. Ross,et al. Noninvasive assessment of the relative roles of cerebral antioxidant enzymes by quantitation of pentose phosphate pathway activity , 1996, Neurochemical Research.
[25] S. Thayer,et al. Mitochondrial Modulation of Ca 2-Induced Ca 2-Release in Rat Sensory Neurons , 2006 .
[26] D. A. Turner,et al. Interaction between tissue oxygen tension and NADH imaging during synaptic stimulation and hypoxia in rat hippocampal slices , 2005, Neuroscience.
[27] Jakub Otáhal,et al. Metabolic dysfunction during neuronal activation in the ex vivo hippocampus from chronic epileptic rats and humans. , 2005, Brain : a journal of neurology.
[28] W. Webb,et al. Conformational Dependence of Intracellular NADH on Metabolic State Revealed by Associated Fluorescence Anisotropy*♦ , 2005, Journal of Biological Chemistry.
[29] A. Aubert,et al. Interaction between Astrocytes and Neurons Studied using a Mathematical Model of Compartmentalized Energy Metabolism , 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[30] Ata Akin,et al. Modelling of calcium dynamics in brain energy metabolism and Alzheimer's disease , 2005, Comput. Biol. Chem..
[31] W. Webb,et al. Neural Activity Triggers Neuronal Oxidative Metabolism Followed by Astrocytic Glycolysis , 2004, Science.
[32] G. Thews. Ein Verfahren zur Bestimmung des O2-Diffusionskoeffizienten, der O2-Leitfähigkeit und des O2-Löslichkeitskoeffizienten im Gehirngewebe , 2004, Pflüger's Archiv für die gesamte Physiologie des Menschen und der Tiere.
[33] S. Schuchmann,et al. Coupling of neuronal activity and mitochondrial metabolism as revealed by nad(p)h fluorescence signals in organotypic hippocampal slice cultures of the rat , 2003, Neuroscience.
[34] S. Schuchmann,et al. Free radical-mediated cell damage after experimental status epilepticus in hippocampal slice cultures. , 2002, Journal of neurophysiology.
[35] G. Dienel,et al. Glucose and lactate metabolism during brain activation , 2001, Journal of neuroscience research.
[36] R Valabrègue,et al. Modelling of the Coupling between Brain Electrical Activity and Metabolism , 2001, Acta biotheoretica.
[37] M. Ward,et al. Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts , 2000, Trends in Neurosciences.
[38] H. Shimoda,et al. Characteristics of monocarboxylates as energy substrates other than glucose in rat brain slices and the effect of selective glial poisoning — a 31P NMR study , 2000, Neuroscience Research.
[39] A. Rex,et al. Cortical NADH during pharmacological manipulations of the respiratory chain and spreading depression in vivo , 1999, Journal of neuroscience research.
[40] L. Sokoloff,et al. Cerebral Oxygen/Glucose Ratio is Low during Sensory Stimulation and Rises above Normal during Recovery: Excess Glucose Consumption during Stimulation is Not Accounted for by Lactate Efflux from or Accumulation in Brain Tissue , 1999, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[41] V. Sogos,et al. Subcellular heterogeneity of mitochondrial membrane potential: relationship with organelle distribution and intercellular contacts in normal, hypoxic and apoptotic cells. , 1999, Journal of cell science.
[42] A. Hudetz,et al. Blood Flow in the Cerebral Capillary Network: A Review Emphasizing Observations with Intravital Microscopy , 1997, Microcirculation.
[43] Helmut Kettenmann,et al. Calcium signalling in glial cells , 1996, Trends in Neurosciences.
[44] A. J. Hulbert,et al. Characteristics of mitochondrial proton leak and control of oxidative phosphorylation in the major oxygen-consuming tissues of the rat. , 1994, Biochimica et biophysica acta.
[45] M. Duchen,et al. Ca(2+)-dependent changes in the mitochondrial energetics in single dissociated mouse sensory neurons. , 1992, The Biochemical journal.
[46] R. M. Hays,et al. ADH-induced depolymerization of F-actin in the toad bladder granular cell: a confocal microscope study. , 1992, The American journal of physiology.
[47] R. Vannucci,et al. Cerebral energy metabolism during hypoxia-ischemia and early recovery in immature rats. , 1992, The American journal of physiology.
[48] P. Bernardi,et al. The K+ conductance of the inner mitochondrial membrane. A study of the inducible uniport for monovalent cations. , 1991, The Journal of biological chemistry.
[49] H. O. Spivey,et al. Metabolic compartmentation. , 1989, BioEssays : news and reviews in molecular, cellular and developmental biology.
[50] A. Schurr,et al. Lactate-supported synaptic function in the rat hippocampal slice preparation. , 1988, Science.
[51] G. Brown,et al. Proton/electron stoichiometry of mitochondrial complex I estimated from the equilibrium thermodynamic force ratio. , 1988, The Biochemical journal.
[52] G. Krishnamoorthy,et al. Non-ohmic proton conductance of mitochondria and liposomes. , 1984, Biochemistry.
[53] B Chance,et al. Pyridine Nucleotide as an Indicator of the Oxygen Requirements for Energy‐Linked Functions of Mitochondria , 1976, Circulation research.
[54] Britton Chance,et al. Metabolic responses of the awake cerebral cortex to anoxia hypoxia spreading depression and epileptiform activity , 1975, Brain Research.
[55] P. Lipton,et al. Effects of membrane depolarization on nicotinamide nucleotide fluorescence in brain slices. , 1973, The Biochemical journal.
[56] L. Sokoloff. Metabolism of ketone bodies by the brain. , 1973, Annual review of medicine.
[57] C. Nicholson,et al. Calcium Transient in Presynaptic Terminal of Auid Giant Synapse: Detection with Aequorin , 1972, Science.
[58] G. Thews. [A method for determination of oxygen diffusion coefficients, oxygen conductivity and oxygen solubility coefficients in brain tissue]. , 1960, Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere.