Evaluation of placental and lactational pharmacokinetics of PFOA and PFOS in the pregnant, lactating, fetal and neonatal rat using a physiologically based pharmacokinetic model.
暂无分享,去创建一个
Harvey J Clewell | Melvin E Andersen | Anne E. Loccisano | Jerry L. Campbell | M. Andersen | H. Clewell | J. Butenhoff | John L Butenhoff | Anne E Loccisano | Jerry L Campbell | J. Campbell
[1] C. Lau,et al. Exposure to perfluorooctane sulfonate during pregnancy in rat and mouse. I: maternal and prenatal evaluations. , 2003, Toxicological sciences : an official journal of the Society of Toxicology.
[2] Konrad Hungerbühler,et al. Estimating Consumer Exposure to PFOS and PFOA , 2008, Risk analysis : an official publication of the Society for Risk Analysis.
[3] A. Koizumi,et al. Human organic anion transporter hOAT4 is a transporter of perfluorooctanoic acid. , 2009, Basic & clinical pharmacology & toxicology.
[4] G. Koren,et al. Designing pregnancy centered medications: drugs which do not cross the human placenta. , 2006, Placenta.
[5] C. Lau,et al. Effects of prenatal perfluorooctane sulfonate (PFOS) exposure on lung maturation in the perinatal rat. , 2005, Birth defects research. Part B, Developmental and reproductive toxicology.
[6] Harvey J Clewell,et al. Evaluating placental transfer and tissue concentrations of manganese in the pregnant rat and fetuses after inhalation exposures with a PBPK model. , 2009, Toxicological sciences : an official journal of the Society of Toxicology.
[7] Anne E. Loccisano,et al. Comparison and evaluation of pharmacokinetics of PFOA and PFOS in the adult rat using a physiologically based pharmacokinetic model. , 2012, Reproductive toxicology.
[8] R. G. York,et al. Neonatal mortality from in utero exposure to perfluorooctanesulfonate (PFOS) in Sprague-Dawley rats: dose-response, and biochemical and pharamacokinetic parameters. , 2005, Toxicology.
[9] W. Liu,et al. Prenatal and postnatal impact of perfluorooctane sulfonate (PFOS) on rat development: a cross-foster study on chemical burden and thyroid hormone system. , 2009, Environmental science & technology.
[10] J. Holson,et al. Blood flow during pregnancy in the rat: II. Dynamics of and litter variability in uterine flow. , 1982, Teratology.
[11] Geary W Olsen,et al. Comparison of human whole blood, plasma, and serum matrices for the determination of perfluorooctanesulfonate (PFOS), perfluorooctanoate (PFOA), and other fluorochemicals. , 2007, Environmental research.
[12] D. Mattie,et al. Predicting age-appropriate pharmacokinetics of six volatile organic compounds in the rat utilizing physiologically based pharmacokinetic modeling. , 2007, Toxicological sciences : an official journal of the Society of Toxicology.
[13] Rebecca A Clewell,et al. Predicting fetal perchlorate dose and inhibition of iodide kinetics during gestation: a physiologically-based pharmacokinetic analysis of perchlorate and iodide kinetics in the rat. , 2003, Toxicological sciences : an official journal of the Society of Toxicology.
[14] Gerald L Kennedy,et al. Comparative responses of rats and mice exposed to linear/branched, linear, or branched ammonium perfluorooctanoate (APFO). , 2006, Toxicology.
[15] W. Slusser,et al. Effect of malnutrition during pregnancy on the development of the mammary glands of rats. , 1981, The Journal of nutrition.
[16] M. Andersen,et al. Lactational transfer of manganese in rats: predicting manganese tissue concentration in the dam and pups from inhalation exposure with a pharmacokinetic model. , 2009, Toxicological sciences : an official journal of the Society of Toxicology.
[17] R. G. York,et al. Two-generation reproduction and cross-foster studies of perfluorooctanesulfonate (PFOS) in rats. , 2005, Toxicology.
[18] A. Calafat,et al. Gestational PFOA exposure of mice is associated with altered mammary gland development in dams and female offspring. , 2006, Toxicological sciences : an official journal of the Society of Toxicology.
[19] A. Calafat,et al. Automated solid-phase extraction and measurement of perfluorinated organic acids and amides in human serum and milk. , 2004, Environmental science & technology.
[20] H. Kusuhara,et al. Gender Difference in the Urinary Excretion of Organic Anions in Rats , 2002, Journal of Pharmacology and Experimental Therapeutics.
[21] G Levy,et al. Serum protein binding of drugs during and after pregnancy in rats. , 1980, The Journal of pharmacology and experimental therapeutics.
[22] Harvey J Clewell,et al. Evaluation and prediction of pharmacokinetics of PFOA and PFOS in the monkey and human using a PBPK model. , 2011, Regulatory toxicology and pharmacology : RTP.
[23] M. Horster,et al. Filtration fraction and extraction of PAH during neonatal period in the rat. , 1970, The American journal of physiology.
[24] D. H. Taylor,et al. Physiologically based pharmacokinetic modeling of the lactating rat and nursing pup: a multiroute exposure model for trichloroethylene and its metabolite, trichloroacetic acid. , 1990, Toxicology and applied pharmacology.
[25] C. Lau,et al. Perfluoroalkyl acids: a review of monitoring and toxicological findings. , 2007, Toxicological sciences : an official journal of the Society of Toxicology.
[26] Gerald L Kennedy,et al. Perfluorooctanoate: Placental and lactational transport pharmacokinetics in rats. , 2005, Toxicology.
[27] F. Lorscheider,et al. Rat alpha-fetoprotein: isolation, radioimmunoassay and fetal-maternal distribution during pregnancy. , 1976, Journal of reproduction and fertility.
[28] J. V. Vanden Heuvel,et al. Lack of evidence for perfluorodecanoyl- or perfluorooctanoyl-coenzyme A formation in male and female rats. , 1992, Journal of biochemical toxicology.
[29] N. Kudo,et al. Rat Organic Anion Transporter 3 and Organic Anion Transporting Polypeptide 1 Mediate Perfluorooctanoic Acid Transport , 2007 .
[30] J. Garcia. Changes in blood, plasma and red cell volume in the male rat, as a function of age. , 1957, The American journal of physiology.
[31] B. Lake. Species differences in the hepatic effects of inducers of CYP2B and CYP4A subfamily forms: relationship to rodent liver tumour formation , 2009, Xenobiotica; the fate of foreign compounds in biological systems.
[32] A. Schecter,et al. Polybrominated Diphenyl Ethers (PBDEs) and Hexabromocyclodecane (HBCD) in Composite U.S. Food Samples , 2009, Environmental health perspectives.
[33] Rebecca A Clewell,et al. Predicting neonatal perchlorate dose and inhibition of iodide uptake in the rat during lactation using physiologically-based pharmacokinetic modeling. , 2003, Toxicological sciences : an official journal of the Society of Toxicology.
[34] K. Teo,et al. Serum levels of perfluoroalkyl compounds in human maternal and umbilical cord blood samples. , 2008, Environmental research.
[35] H. Barton,et al. Predicting maternal rat and pup exposures: how different are they? , 2008, Toxicological sciences : an official journal of the Society of Toxicology.
[36] Harvey J Clewell,et al. Time dependencies in perfluorooctylacids disposition in rat and monkeys: a kinetic analysis. , 2008, Toxicology letters.
[37] Tim Morris,et al. Physiological Parameters in Laboratory Animals and Humans , 1993, Pharmaceutical Research.
[38] D. Richardson,et al. The utilization of protein and energy during lactation in the rat, with particular regard to the use of fat accumulated in pregnancy , 1982, British Journal of Nutrition.
[39] Dowell Rt,et al. Maternal hemodynamics and uteroplacental blood flow throughout gestation in conscious rats. , 1997 .
[40] C. Lau,et al. Developmental toxicity of perfluorooctane sulfonate (PFOS) is not dependent on expression of peroxisome proliferator activated receptor-alpha (PPAR alpha) in the mouse. , 2009, Reproductive toxicology.
[41] Harvey J Clewell,et al. Pharmacokinetic modeling of saturable, renal resorption of perfluoroalkylacids in monkeys--probing the determinants of long plasma half-lives. , 2006, Toxicology.
[42] Melvin E Andersen,et al. Tissue exposures to free and glucuronidated monobutylyphthalate in the pregnant and fetal rat following exposure to di-n-butylphthalate: evaluation with a PBPK model. , 2008, Toxicological sciences : an official journal of the Society of Toxicology.
[43] C. Lau,et al. The developmental toxicity of perfluoroalkyl acids and their derivatives. , 2004, Toxicology and applied pharmacology.
[44] Xing Han,et al. Organic anion transporting polypeptide (Oatp) 1a1-mediated perfluorooctanoate transport and evidence for a renal reabsorption mechanism of Oatp1a1 in renal elimination of perfluorocarboxylates in rats. , 2009, Toxicology letters.
[45] C. Lau,et al. Effects of perfluorooctanoic acid exposure during pregnancy in the mouse. , 2006, Toxicological sciences : an official journal of the Society of Toxicology.
[46] S. Fenton,et al. Analysis of PFOA in dosed CD-1 mice. Part 2. Disposition of PFOA in tissues and fluids from pregnant and lactating mice and their pups. , 2009, Reproductive toxicology.
[47] M. Stanton,et al. Exposure to perfluorooctane sulfonate during pregnancy in rat and mouse. II: postnatal evaluation. , 2003, Toxicological sciences : an official journal of the Society of Toxicology.
[48] A. Rudolph,et al. Effects of cord compression on fetal blood flow distribution and O2 delivery. , 1987, The American journal of physiology.
[49] A. Bergman,et al. A temporal trend study (1972-2008) of perfluorooctanesulfonate, perfluorohexanesulfonate, and perfluorooctanoate in pooled human milk samples from Stockholm, Sweden. , 2011, Environment international.
[50] J. Taylor,et al. Changes in rat alpha 1-fetoprotein and albumin mRNA levels during fetal and neonatal development. , 1980, The Journal of biological chemistry.
[51] Jørn Olsen,et al. Perfluorinated Chemicals and Fetal Growth: A Study within the Danish National Birth Cohort , 2007, Environmental health perspectives.
[52] J. Kim,et al. Molecular Cloning and Characterization of Multispecific Organic Anion Transporter 4 Expressed in the Placenta* , 2000, The Journal of Biological Chemistry.
[53] Sikov Mr,et al. Prenatal growth of the rat. , 1970 .
[54] D. Stump,et al. Gestational and lactational exposure to potassium perfluorooctanesulfonate (K+PFOS) in rats: developmental neurotoxicity. , 2009, Reproductive toxicology.
[55] Xing Han,et al. Characterization of cellular uptake of perfluorooctanoate via organic anion-transporting polypeptide 1A2, organic anion transporter 4, and urate transporter 1 for their potential roles in mediating human renal reabsorption of perfluorocarboxylates. , 2010, Toxicological sciences : an official journal of the Society of Toxicology.
[56] Rolf U Halden,et al. Determinants of fetal exposure to polyfluoroalkyl compounds in Baltimore, Maryland. , 2007, Environmental science & technology.
[57] John W. Froehlich,et al. Half-Life of Serum Elimination of Perfluorooctanesulfonate,Perfluorohexanesulfonate, and Perfluorooctanoate in Retired Fluorochemical Production Workers , 2007, Environmental health perspectives.
[58] H. Schneider. Placental transport function. , 1991, Reproduction, fertility, and development.
[59] J. Johnson,et al. Cholestyramine-enhanced fecal elimination of carbon-14 in rats after administration of ammonium [14C]perfluorooctanoate or potassium [14C]perfluorooctanesulfonate. , 1984, Fundamental and applied toxicology : official journal of the Society of Toxicology.
[60] C. Lau,et al. Perfluorooctanoic acid induced developmental toxicity in the mouse is dependent on expression of peroxisome proliferator activated receptor-alpha. , 2007, Toxicological sciences : an official journal of the Society of Toxicology.
[61] A. Calafat,et al. Developmental toxicity of perfluorooctanoic acid in the CD-1 mouse after cross-foster and restricted gestational exposures. , 2006, Toxicological sciences : an official journal of the Society of Toxicology.
[62] G. W. Jepson,et al. Binding of perfluorooctanoic acid to rat and human plasma proteins. , 2003, Chemical research in toxicology.
[63] J. V. Vanden Heuvel,et al. Tissue distribution, metabolism, and elimination of perfluorooctanoic acid in male and female rats. , 1991, Journal of biochemical toxicology.
[64] Y. Kanai,et al. Roles of organic anion transporters in the renal excretion of perfluorooctanoic acid. , 2008, Basic & clinical pharmacology & toxicology.
[65] J. Atherton. Glomerular filtration rate and salt and water reabsorption during pregnancy in the conscious rat. , 1983, The Journal of physiology.
[66] Yoichi Kawashima,et al. Toxicity and toxicokinetics of perfluorooctanoic acid in humans and animals. , 2003, The Journal of toxicological sciences.
[67] S. Choudhuri,et al. Gender-specific and developmental influences on the expression of rat organic anion transporters. , 2002, The Journal of pharmacology and experimental therapeutics.
[68] N. Kudo,et al. Sex hormone-regulated renal transport of perfluorooctanoic acid. , 2002, Chemico-biological interactions.
[69] Wenyue Hu,et al. Binding of perfluorinated fatty acids to serum proteins , 2003, Environmental toxicology and chemistry.
[70] S. Henning. Postnatal development: coordination of feeding, digestion, and metabolism. , 1981, The American journal of physiology.
[71] B. Shirley. The food intake of rats during pregnancy and lactation. , 1984, Laboratory animal science.
[72] Harvey J Clewell,et al. Exposure assessment and risk characterization for perfluorooctanoate in selected consumer articles. , 2005, Environmental science & technology.
[73] J L Linzell,et al. The time course of cardiovascular changes in lactation in the rat , 1973, The Journal of physiology.
[74] F. Gonzalez,et al. PPARalpha: mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators. , 2008, Toxicology.
[75] R. Setzer,et al. Pharmacokinetic modeling of perfluorooctanoic acid during gestation and lactation in the mouse. , 2009, Reproductive toxicology.
[76] K. Conrad. Renal hemodynamics during pregnancy in chronically catheterized, conscious rats. , 1984, Kidney international.
[77] L. Shaw,et al. Community Exposure to Perfluorooctanoate: Relationships Between Serum Concentrations and Exposure Sources , 2006, Journal of occupational and environmental medicine.
[78] A. Aperia,et al. Distal tubular sodium reabsorption in the developing rat kidney. , 1981, The American journal of physiology.
[79] M. Beckmann,et al. Transplacental exposure of neonates to perfluorooctanesulfonate and perfluorooctanoate: a pilot study , 2007, International archives of occupational and environmental health.
[80] P. Hinderliter,et al. Age effect on perfluorooctanoate (PFOA) plasma concentration in post-weaning rats following oral gavage with ammonium perfluorooctanoate (APFO). , 2006, Toxicology.
[81] Marie Aune,et al. Exposure of Perfluorinated Chemicals through Lactation: Levels of Matched Human Milk and Serum and a Temporal Trend, 1996–2004, in Sweden , 2006, Environmental health perspectives.
[82] Nathan M. Bass,et al. Interactions of flurochemicals with rat liver fatty acid-binding protein , 2002 .
[83] C. Klaassen,et al. Rat and mouse differences in gender-predominant expression of organic anion transporter (Oat1-3; Slc22a6-8) mRNA levels. , 2004, Drug metabolism and disposition: the biological fate of chemicals.
[84] G. Olsen,et al. Perfluoroalkyl chemicals and human fetal development: an epidemiologic review with clinical and toxicological perspectives. , 2009, Reproductive toxicology.
[85] R H Ophaug,et al. Metabolic Handling of Perfluorooctanoic Acid in Rats , 1980, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.
[86] M. Delp,et al. Physiological Parameter Values for Physiologically Based Pharmacokinetic Models , 1997, Toxicology and industrial health.
[87] D. Ehresman,et al. Roles of rat renal organic anion transporters in transporting perfluorinated carboxylates with different chain lengths. , 2010, Toxicological sciences : an official journal of the Society of Toxicology.
[88] J. Goedbloed. Embryonic and postnatal growth of rat and mouse. V. Prenatal growth of organs and tissues, general principles: allometric growth, absence of growth, and the genetic regulation of the growth process. , 1976, Acta anatomica.
[89] Yoichi Kawashima,et al. Tissue distribution and hepatic subcellular distribution of perfluorooctanoic acid at low dose are different from those at high dose in rats. , 2007, Biological & pharmaceutical bulletin.
[90] P. Rosso. Changes in the transfer of nutrients across the placenta during normal gestation in the rat. , 1975, American journal of obstetrics and gynecology.
[91] Melvin E Andersen,et al. Perfluoroalkyl acids and related chemistries--toxicokinetics and modes of action. , 2008, Toxicological sciences : an official journal of the Society of Toxicology.
[92] R. Luthy,et al. Binding of perfluorocarboxylates to serum albumin: a comparison of analytical methods. , 2010, Analytical chemistry.
[93] D. Stump,et al. Gestational and lactational exposure to potassium perfluorooctanesulfonate (K+PFOS) in rats: toxicokinetics, thyroid hormone status, and related gene expression. , 2009, Reproductive toxicology.
[94] A. Calafat,et al. Polyfluoroalkyl Chemicals in the U.S. Population: Data from the National Health and Nutrition Examination Survey (NHANES) 2003–2004 and Comparisons with NHANES 1999–2000 , 2007, Environmental health perspectives.
[95] M S Christian,et al. Rat and rabbit oral developmental toxicology studies with two perfluorinated compounds. , 2001, International journal of toxicology.
[96] C. Klaassen,et al. The presence of xenobiotic transporters in rat placenta. , 2003, Drug metabolism and disposition: the biological fate of chemicals.
[97] A. Calafat,et al. Polyfluoroalkyl chemicals in the serum and milk of breastfeeding women. , 2009, Reproductive toxicology.
[98] S. Mabury,et al. Disposition of perfluorinated acid isomers in sprague‐dawley rats; Part 1: Single dose , 2009, Environmental toxicology and chemistry.
[99] G. Olsen,et al. Subchronic toxicity studies on perfluorooctanesulfonate potassium salt in cynomolgus monkeys. , 2002, Toxicological sciences : an official journal of the Society of Toxicology.
[100] J. Wambaugh,et al. Modeling single and repeated dose pharmacokinetics of PFOA in mice. , 2009, Toxicological sciences : an official journal of the Society of Toxicology.
[101] J. Fisher,et al. Organ Growth Functions in Maturing Male Sprague-Dawley Rats , 2007, Journal of toxicology and environmental health. Part A.
[102] W. Liu,et al. Transcriptional effects of prenatal and neonatal exposure to PFOS in developing rat brain. , 2010, Environmental science & technology.
[103] E J O'Flaherty,et al. A physiologically based kinetic model of rat and mouse gestation: disposition of a weak acid. , 1992, Toxicology and applied pharmacology.