Modulation of synaptic plasticity by brain estrogen in the hippocampus.

[1]  Aoyagi-Usui Midori.  A Comparative Analysis of Citizen's Environmental Values and Pro-environmental Behavior , 1998 .

[2]  Michael Frotscher,et al.  Hippocampal Synapses Depend on Hippocampal Estrogen Synthesis , 2004, The Journal of Neuroscience.

[3]  P. Chambon,et al.  The AF-1 activation-function of ERα may be dispensable to mediate the effect of estradiol on endothelial NO production in mice , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[4]  E. Prossnitz,et al.  Expression of G protein-coupled receptor-30, a G protein-coupled membrane estrogen receptor, in oxytocin neurons of the rat paraventricular and supraoptic nuclei. , 2007, Endocrinology.

[5]  M. Ogiue-Ikeda,et al.  Estrogen synthesis in the brain—Role in synaptic plasticity and memory , 2008, Molecular and Cellular Endocrinology.

[6]  S. Belcher,et al.  Estrogenic actions in the brain: estrogen, phytoestrogens, and rapid intracellular signaling mechanisms. , 2001, The Journal of pharmacology and experimental therapeutics.

[7]  P. Chambon,et al.  Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes. , 2000, Development.

[8]  N. Maidment,et al.  Forebrain steroid levels fluctuate rapidly during social interactions , 2008, Nature Neuroscience.

[9]  J. Dong,et al.  Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. , 2005, Endocrinology.

[10]  M. Cyr,et al.  Ovarian steroids and selective estrogen receptor modulators activity on rat brain NMDA and AMPA receptors , 2001, Brain Research Reviews.

[11]  G. Ball,et al.  Fast regulation of steroid biosynthesis: a further piece in the neurosteroid puzzle , 2000, Trends in Neurosciences.

[12]  A. Wenzel,et al.  Synapse‐specific localization of NMDA and GABAA receptor subunits revealed by antigen‐retrieval immunohistochemistry , 1998, The Journal of comparative neurology.

[13]  J. Morrison,et al.  Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017alpha and P450 aromatase localized in neurons. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[14]  J. Ávila,et al.  Estradiol inhibits GSK3 and regulates interaction of estrogen receptors, GSK3, and beta-catenin in the hippocampus , 2004, Molecular and Cellular Neuroscience.

[15]  S. Kawato,et al.  Retinoic acid stimulates 17beta-estradiol and testosterone synthesis in rat hippocampal slice cultures. , 2009, Endocrinology.

[16]  Jacques Balthazart,et al.  Is brain estradiol a hormone or a neurotransmitter? , 2006, Trends in Neurosciences.

[17]  E. Levin,et al.  Nature of functional estrogen receptors at the plasma membrane. , 2006, Molecular endocrinology.

[18]  Meharvan Singh,et al.  Novel Mechanisms of Estrogen Action in the Brain: New Players in an Old Story , 1999, Frontiers in Neuroendocrinology.

[19]  B. Katzenellenbogen,et al.  Activities of estrogen receptor alpha- and beta-selective ligands at diverse estrogen responsive gene sites mediating transactivation or transrepression , 2003, Molecular and Cellular Endocrinology.

[20]  C. Deschepper,et al.  Neurosteroid biosynthesis: genes for adrenal steroidogenic enzymes are expressed in the brain , 1993, Brain Research.

[21]  A. Arnold,et al.  Circulating estrogens in a male songbird originate in the brain. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[22]  G. Rune,et al.  Steroidogenic factor‐1 expression in marmoset and rat hippocampus: co‐localization with StAR and aromatase , 2001, Journal of neurochemistry.

[23]  Michael Schoen,et al.  Gonadotropin-releasing hormone regulates spine density via its regulatory role in hippocampal estrogen synthesis , 2008, The Journal of cell biology.

[24]  T. Tsurugizawa,et al.  Neurosteroid synthesis by cytochrome p450-containing systems localized in the rat brain hippocampal neurons: N-methyl-D-aspartate and calcium-dependent synthesis. , 2001, Endocrinology.

[25]  Kehinde A. Ayoola,et al.  Ultrastructural localization of estrogen receptor β immunoreactivity in the rat hippocampal formation , 2005, The Journal of comparative neurology.

[26]  C. Woolley.  Estrogen-Mediated Structural and Functional Synaptic Plasticity in the Female Rat Hippocampus , 1998, Hormones and Behavior.

[27]  L. Amaducci,et al.  Estrogen-replacement therapy and Alzheimer's disease in the Italian Longitudinal Study on Aging , 1998, Neurology.

[28]  H. Mukai,et al.  Comparison between hippocampus-synthesized and circulation-derived sex steroids in the hippocampus. , 2009, Endocrinology.

[29]  C. Beyer,et al.  Ontogenetic expression and sex differences of aromatase and estrogen receptor-α/β mRNA in the mouse hippocampus , 2000, Cell and Tissue Research.

[30]  C. Beyer,et al.  Ontogenetic expression and sex differences of aromatase and estrogen receptor-alpha/beta mRNA in the mouse hippocampus. , 2000, Cell and tissue research.

[31]  C. Woolley,et al.  Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood , 1990, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[32]  K. Korach,et al.  Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene. , 1995, Molecular endocrinology.

[33]  Robert B. Wallace,et al.  Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial. , 2003 .

[34]  F. Gannon,et al.  Down but not out? A novel protein isoform of the estrogen receptor alpha is expressed in the estrogen receptor alpha knockout mouse. , 2002, Journal of molecular endocrinology.

[35]  C. Léránth,et al.  The 17alpha and 17beta isomers of estradiol both induce rapid spine synapse formation in the CA1 hippocampal subfield of ovariectomized female rats. , 2005, Endocrinology.

[36]  C. Léránth,et al.  The 17α and 17β Isomers of Estradiol Both Induce Rapid Spine Synapse Formation in the CA1 Hippocampal Subfield of Ovariectomized Female Rats , 2005 .

[37]  C. Léránth,et al.  Hormonal regulation of hippocampal spine synapse density involves subcortical mediation , 2000, Neuroscience.

[38]  V. Papadopoulos.  Peripheral-type benzodiazepine/diazepam binding inhibitor receptor: biological role in steroidogenic cell function. , 1993, Endocrine reviews.

[39]  R. Morris,et al.  Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein , 1998, Nature.

[40]  T. Horvath,et al.  Presynaptic N‐methyl‐D‐aspartate receptor expression is increased by estrogen in an aromatase‐rich area of the songbird hippocampus , 2004, The Journal of comparative neurology.

[41]  T. Teyler,et al.  Gonadal steroids: effects on excitability of hippocampal pyramidal cells. , 1980, Science.

[42]  T. Tsurugizawa,et al.  Rapid modulation of synaptic plasticity by estrogens as well as endocrine disrupters in hippocampal neurons , 2008, Brain Research Reviews.

[43]  R. Zucker,et al.  Selective induction of LTP and LTD by postsynaptic [Ca2+]i elevation. , 1999, Journal of neurophysiology.

[44]  Tudor I. Oprea,et al.  Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system. , 2007, The Journal of endocrinology.

[45]  L. Garcia-Segura,et al.  Steroidogenic acute regulatory protein in the brain , 2006, Neuroscience.

[46]  M. Numazawa,et al.  Highly sensitive determination of estrone and estradiol in human serum by liquid chromatography–electrospray ionization tandem mass spectrometry , 2007, Steroids.

[47]  J. Morrison,et al.  Differential Regulation of NMDAR1 mRNA and Protein by Estradiol in the Rat Hippocampus , 1996, The Journal of Neuroscience.

[48]  T. Tsurugizawa,et al.  Role of Cytochrome P450 in Synaptocrinology: Endogenous Estrogen Synthesis in the Brain Hippocampus , 2006, Drug metabolism reviews.

[49]  J. Morrison,et al.  Rapid modulation of long‐term depression and spinogenesis via synaptic estrogen receptors in hippocampal principal neurons , 2007, Journal of neurochemistry.

[50]  W. Griffiths,et al.  Neurosteroids in rat brain: extraction, isolation, and analysis by nanoscale liquid chromatography-electrospray mass spectrometry. , 2003, Analytical chemistry.

[51]  C. Elger,et al.  Expression of mRNAs encoding for 17β-hydroxisteroid dehydrogenase isozymes 1, 2, 3 and 4 in epileptic human hippocampus , 2000, Epilepsy Research.

[52]  M. Schumacher,et al.  Validation of an analytical procedure to measure trace amounts of neurosteroids in brain tissue by gas chromatography-mass spectrometry. , 2000, Journal of chromatography. B, Biomedical sciences and applications.

[53]  J. Morrison,et al.  Estrogen induces rapid decrease in dendritic thorns of CA3 pyramidal neurons in adult male rat hippocampus. , 2005, Biochemical and biophysical research communications.

[54]  C. Léránth,et al.  Effects of dehydroepiandrosterone and flutamide on hippocampal CA1 spine synapse density in male and female rats: implications for the role of androgens in maintenance of hippocampal structure. , 2004, Endocrinology.

[55]  C. Cotman,et al.  Anatomical distributions of four pharmacologically distinct 3H-L-glutamate binding sites , 1983, Nature.

[56]  T. Tsurugizawa,et al.  Local Neurosteroid Production in the Hippocampus: Influence on Synaptic Plasticity of Memory , 2007, Neuroendocrinology.

[57]  J. Honour,et al.  Identification of neuroactive steroids and their precursors and metabolites in adult male rat brain. , 2006, Endocrinology.

[58]  高浪 景子.  Expression of G protein-coupled receptor 30 in the spinal somatosensory system , 2010 .

[59]  D. Paolo,et al.  Regional and Selective Effects of Oestradiol and Progesterone on NMDA and AMPA Receptors in the Rat Brain , 2000, Journal of neuroendocrinology.

[60]  T. Berger,et al.  17beta-estradiol enhances NMDA receptor-mediated EPSPs and long-term potentiation. , 1999, Journal of neurophysiology.

[61]  S. Kawato,et al.  Brain neurosteroids are 4th generation neuromessengers in the brain: cell biophysical analysis of steroid signal transduction. , 2003, Advances in biophysics.

[62]  N. Weiland.  Estradiol selectively regulates agonist binding sites on the N-methyl-D-aspartate receptor complex in the CA1 region of the hippocampus. , 1992, Endocrinology.

[63]  Michael S. Brainard,et al.  What songbirds teach us about learning , 2002, Nature.

[64]  M. Schumacher,et al.  Developmental Expression of Genes Involved in Neurosteroidogenesis: 3β-Hydroxysteroid Dehydrogenase/Δ5-Δ4 Isomerase in the Rat Brain , 2003 .

[65]  T. Tsurugizawa,et al.  Local Production of Sex Hormones and Their Modulation of Hippocampal Synaptic Plasticity , 2007, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

[66]  J. Sanne,et al.  Expression of Cytochrome P450 Side‐Chain Cleavage Enzyme and 3β‐Hydroxysteroid Dehydrogenase in the Rat Central Nervous System: A Study by Polymerase Chain Reaction and In Situ Hybridization , 1995, Journal of neurochemistry.

[67]  T. Higashi,et al.  Studies on neurosteroids XVI. Levels of pregnenolone sulfate in rat brains determined by enzyme-linked immunosorbent assay not requiring solvolysis. , 2003, Biological & pharmaceutical bulletin.

[68]  T. Inoue,et al.  Estradiol increases spine density and NMDA-dependent Ca2+ transients in spines of CA1 pyramidal neurons from hippocampal slices. , 1999, Journal of neurophysiology.

[69]  S. Kawato.  Endocrine disrupters as disrupters of brain function: a neurosteroid viewpoint. , 2004, Environmental sciences : an international journal of environmental physiology and toxicology.

[70]  R. L. Moss,et al.  Printed in U.S.A. Copyright © 1999 by The Endocrine Society Rapid Action of 17�-Estradiol on Kainate-Induced Currents in Hippocampal Neurons Lacking Intracellular , 2022 .

[71]  R. L. Moss,et al.  17β-Estradiol Potentiates Kainate-Induced Currents via Activation of the cAMP Cascade , 1996, The Journal of Neuroscience.

[72]  A. Routtenberg,et al.  Gene expression of the transcription factor NF-kappa B in hippocampus: regulation by synaptic activity. , 1996, Brain research. Molecular brain research.

[73]  M. Segal,et al.  Regulation of Dendritic Spine Density in Cultured Rat Hippocampal Neurons by Steroid Hormones , 1996, The Journal of Neuroscience.

[74]  B. Mcewen,et al.  Estradiol regulates hippocampal dendritic spine density via an N-methyl- D-aspartate receptor-dependent mechanism , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[75]  G. Greene,et al.  Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: studies of ERalpha and ERbeta expressed in Chinese hamster ovary cells. , 1999, Molecular endocrinology.

[76]  T. Tsurugizawa,et al.  Comparison between basal and apical dendritic spines in estrogen-induced rapid spinogenesis of CA1 principal neurons in the adult hippocampus. , 2006, Biochemical and biophysical research communications.

[77]  T. Tsurugizawa,et al.  Rapid spinogenesis of pyramidal neurons induced by activation of glucocorticoid receptors in adult male rat hippocampus. , 2005, Biochemical and biophysical research communications.

[78]  S. Kawato,et al.  Comparison of sex steroid synthesis between neonatal and adult rat hippocampus , 2009, Neuroscience Research.

[79]  A. C. Collins,et al.  Conditional Expression in Corticothalamic Efferents Reveals a Developmental Role for Nicotinic Acetylcholine Receptors in Modulation of Passive Avoidance Behavior , 2003, The Journal of Neuroscience.

[80]  A. Fine,et al.  Postsynaptic Calcium Transients Evoked by Activation of Individual Hippocampal Mossy Fiber Synapses , 2001, The Journal of Neuroscience.

[81]  A. Paganini-Hill.  Oestrogen replacement therapy and Alzheimer's disease. , 1996, British journal of obstetrics and gynaecology.

[82]  J. Gustafsson,et al.  Nongenomic effects of estrogen: Why all the uncertainty? , 2006, Steroids.

[83]  N. Takata,et al.  Hippocampal synthesis of estrogens and androgens which are paracrine modulators of synaptic plasticity: Synaptocrinology , 2006, Neuroscience.

[84]  N. Clayton,et al.  Neural aromatization accelerates the acquisition of spatial memory via an influence on the songbird hippocampus , 2004, Hormones and Behavior.

[85]  B. Mcewen,et al.  Estradiol mediates fluctuation in hippocampal synapse density during the estrous cycle in the adult rat [published erratum appears in J Neurosci 1992 Oct;12(10):following table of contents] , 1992, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[86]  Bruce S. McEwen,et al.  Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons , 1990, Brain Research.

[87]  T. Hicks,et al.  Age‐dependent, steroid‐specific effects of oestrogen on long‐term potentiation in rat hippocampal slices , 1999, The Journal of physiology.

[88]  Robert B Wallace,et al.  Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial. , 2003, JAMA.

[89]  E G Tangalos,et al.  Postmenopausal estrogen replacement therapy and risk of AD , 1999, Neurology.

[90]  H. Mukai,et al.  Androgen rapidly increases dendritic thorns of CA3 neurons in male rat hippocampus. , 2009, Biochemical and biophysical research communications.

[91]  Eric R. Prossnitz,et al.  A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling , 2005, Science.

[92]  J. Lisman,et al.  A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[93]  M. Baudry,et al.  The tyrosine kinase and mitogen-activated protein kinase pathways mediate multiple effects of estrogen in hippocampus. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[94]  G. Ball,et al.  Seasonal and hormonal modulation of neurotransmitter systems in the song control circuit , 2010, Journal of Chemical Neuroanatomy.

[95]  S. Schultz.  Principles of Neural Science, 4th ed. , 2001 .

[96]  C. Webb,et al.  Estrogen hits the surface , 1999, Nature Medicine.

[97]  S. Kawato,et al.  Histological and metabolism analysis of P450 expression in the brain. , 2002, Methods in enzymology.

[98]  L. McMahon,et al.  Estrogen-Induced Increase in the Magnitude of Long-Term Potentiation Occurs Only When the Ratio of NMDA Transmission to AMPA Transmission Is Increased , 2005, The Journal of Neuroscience.

[99]  H. Carrer,et al.  Estrogen facilitates induction of long term potentiation in the hippocampus of awake rats 1 First published on the World Wide Web on 4 November 1997. 1 , 1997, Brain Research.

[100]  M. Gahr,et al.  Hormonal influence on song structure and organization: The role of estrogen , 2006, Neuroscience.

[101]  Akihiko Takashima,et al.  GSK-3 is essential in the pathogenesis of Alzheimer's disease. , 2006, Journal of Alzheimer's disease : JAD.

[102]  L. Garcia-Segura,et al.  Cross-talk between estrogen receptors and insulin-like growth factor-I receptor in the brain: Cellular and molecular mechanisms , 2006, Frontiers in Neuroendocrinology.

[103]  R. Brookmeyer,et al.  A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease , 1997, Neurology.

[104]  Mark F Bear,et al.  NMDA Induces Long-Term Synaptic Depression and Dephosphorylation of the GluR1 Subunit of AMPA Receptors in Hippocampus , 1998, Neuron.

[105]  Erminio Costa,et al.  Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis , 2006, Proceedings of the National Academy of Sciences.

[106]  C. Léránth,et al.  Gonadal Hormones Affect Spine Synaptic Density in the CA1 Hippocampal Subfield of Male Rats , 2003, The Journal of Neuroscience.

[107]  H. Lauke,et al.  Inhibition of hippocampal estrogen synthesis causes region‐specific downregulation of synaptic protein expression in hippocampal neurons , 2006, Hippocampus.

[108]  L. McMahon,et al.  Estradiol-Induced Increase in the Magnitude of Long-Term Potentiation Is Prevented by Blocking NR2B-Containing Receptors , 2006, The Journal of Neuroscience.

[109]  G. Rune,et al.  Proliferation and apoptosis of hippocampal granule cells require local oestrogen synthesis , 2006, Journal of neurochemistry.

[110]  E. Baulieu,et al.  Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) as neuroactive neurosteroids. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[111]  P. Somogyi,et al.  High-resolution immunogold localization of AMPA type glutamate receptor subunits at synaptic and non-synaptic sites in rat hippocampus , 1995, Neuroscience.

[112]  C. Reid.  The role of dendritic spines: comparing the complex with the simple. , 2002, European journal of pharmacology.

[113]  N. Takata,et al.  Hippocampal cytochrome P450s synthesize brain neurosteroids which are paracrine neuromodulators of synaptic signal transduction. , 2003, Biochimica et biophysica acta.

[114]  Richard F. Thompson,et al.  17β-Estradiol Enhances NMDA Receptor-Mediated EPSPs and Long-Term Potentiation , 1999 .