High expression of telomerase is an independent prognostic indicator of poor outcome in hepatoblastoma

[1]  Y. Hata The clinical features and prognosis of hepatoblastoma: Follow-up studies done on pediatric tumors enrolled in the Japanese pediatric tumor registry between 1971 and 1980. Part I , 1990, The Japanese journal of surgery.

[2]  W. Hahn,et al.  Telomerase Maintains Telomere Structure in Normal Human Cells , 2003, Cell.

[3]  G. Saretzki Telomerase inhibition as cancer therapy. , 2003, Cancer letters.

[4]  M. Finegold Chemotherapy for suspected hepatoblastoma without efforts at surgical resection is a bad practice. , 2002, Medical and pediatric oncology.

[5]  D. V. von Schweinitz,et al.  Pretreatment prognostic factors and treatment results in children with hepatoblastoma , 2002, Cancer.

[6]  N. Ohnuma,et al.  Outcome of hepatoblastoma treated with the JPLT-1 (Japanese Study Group for Pediatric Liver Tumor) Protocol-1: A report from the Japanese Study Group for Pediatric Liver Tumor. , 2002, Journal of pediatric surgery.

[7]  E. Hiyama,et al.  High‐dose chemotherapy in children with metastatic hepatoblastoma , 2002, Pediatrics international : official journal of the Japan Pediatric Society.

[8]  S. Albrecht,et al.  Prognostic impact of molecular genetic alterations in hepatoblastoma. , 2002, Medical and pediatric oncology.

[9]  C. Papadimitriou,et al.  Expression of human telomerase reverse transcriptase in regenerative and precancerous lesions of cirrhotic livers. , 2002, Liver.

[10]  E. Hiyama,et al.  Clinical utility of telomerase in cancer , 2002, Oncogene.

[11]  Y. Naito,et al.  Telomerase Activity and Expression of Telomerase RNA Component and Catalytic Subunits in Precancerous and Cancerous Colorectal Lesions , 2001, Tumor Biology.

[12]  H. Harn,et al.  In situ detection of hTERT mRNA relates to Ki-67 labeling index in papillary thyroid carcinoma. , 2001, The Journal of surgical research.

[13]  A. Nakagawara,et al.  Frequent deletions and mutations of the beta-catenin gene are associated with overexpression of cyclin D1 and fibronectin and poorly differentiated histology in childhood hepatoblastoma. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

[14]  V. Ferrans,et al.  Telomerase activity and expression of human telomerase RNA component and human telomerase reverse transcriptase in lung carcinomas. , 2001, Human pathology.

[15]  J. Shay,et al.  Immunohistochemical detection of telomerase (hTERT) protein in human cancer tissues and a subset of cells in normal tissues. , 2001, Neoplasia.

[16]  G. Perilongo,et al.  Pretreatment prognostic factors for children with hepatoblastoma-- results from the International Society of Paediatric Oncology (SIOP) study SIOPEL 1. , 2000, European journal of cancer.

[17]  J. Shay,et al.  High telomerase activity is an independent prognostic indicator of poor outcome in colorectal cancer. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

[18]  立本 直邦 High telomerase activity is an independent prognostic indicator of poor outcome in colorectal cancer , 2000 .

[19]  N. Breslow,et al.  High telomerase reverse transcriptase (hTERT) messenger RNA level correlates with tumor recurrence in patients with favorable histology Wilms' tumor. , 1999, Cancer research.

[20]  A. Marchetti,et al.  Telomerase activity as a prognostic indicator in stage I non-small cell lung cancer. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

[21]  J. Fujimoto,et al.  Immunohistochemical Detection of Human Telomerase Reverse Transcriptase in Normal Mucosa and Precancerous Lesions of the Stomach , 1999, Japanese journal of cancer research : Gann.

[22]  G. Hagen,et al.  Genomic organization and promoter characterization of the gene encoding the human telomerase reverse transcriptase (hTERT). , 1999, Gene.

[23]  S. Albrecht,et al.  Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene. , 1999, Cancer research.

[24]  M. DeBaun,et al.  Hemihypertrophy and a poorly differentiated embryonal rhabdomyosarcoma of the pelvis. , 1999, Medical and pediatric oncology.

[25]  D. V. von Schweinitz,et al.  Prognostic factors and staging systems in childhood hepatoblastoma , 1997, International journal of cancer.

[26]  J. Shay,et al.  Telomerase activity for the preoperative diagnosis of pancreatic cancer. , 1997, Journal of the National Cancer Institute.

[27]  J. Shay,et al.  Telomerase activity in neuroblastoma: is it a prognostic indicator of clinical behaviour? , 1997, European journal of cancer.

[28]  T. Ide,et al.  Significance of telomerase activity in the diagnosis of small differentiated hepatocellular carcinoma , 1997, International journal of cancer.

[29]  J. Shay,et al.  A survey of telomerase activity in human cancer. , 1997, European journal of cancer.

[30]  J. Shay,et al.  Telomerase activity is detected in pancreatic cancer but not in benign tumors. , 1997, Cancer research.

[31]  J. Shay,et al.  Telomerase assays in the diagnosis and prognosis of cancer. , 1997, Ciba Foundation symposium.

[32]  H. Stein,et al.  [Telomerase as a tumor marker?]. , 1997, Verhandlungen der Deutschen Gesellschaft fur Pathologie.

[33]  B. Gallie,et al.  Development of retinoblastoma in the absence of telomerase activity. , 1996, Journal of the National Cancer Institute.

[34]  K. Nouso,et al.  Telomerase as a tool for the differential diagnosis of human hepatocellular carcinoma , 1996, Cancer.

[35]  J. Shay,et al.  Telomerase activity in gastric cancer. , 1995, Cancer research.

[36]  S. Gallinger,et al.  Telomerase activity associated with acquisition of malignancy in human colorectal cancer. , 1995, Cancer research.

[37]  Keiko Hiyama,et al.  Correlating telomerase activity levels with human neuroblastoma outcomes , 1995, Nature Medicine.

[38]  J. Shay,et al.  Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol (TRAP) , 1995 .

[39]  J. Shay,et al.  Forward: Aging and cancer: Are telomeres and telomerase the connection? , 2001 .

[40]  C B Harley,et al.  Specific association of human telomerase activity with immortal cells and cancer. , 1994, Science.

[41]  A. von Deimling,et al.  Loss of maternal alleles on chromosome arm 11p in hepatoblastoma. , 1994, Cancer research.

[42]  C. Harley,et al.  Telomerase, cell immortality, and cancer. , 1994, Cold Spring Harbor symposia on quantitative biology.

[43]  Y. Hata The clinical features and prognosis of hepatoblastoma: follow-up studies done on pediatric tumors enrolled in the Japanese Pediatric Tumor Registry between 1971 and 1980. Part I. Committee of Malignant Tumors, Japanese Society of Pediatric Surgeons. , 1990, The Japanese journal of surgery.

[44]  K. Muczynski,et al.  Histopathology and prognosis in childhood hepatoblastoma and hepatocarcinoma , 1989, Cancer.

[45]  V A Zakian,et al.  Structure and function of telomeres. , 1989, Annual review of genetics.

[46]  P. Chomczyński,et al.  Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. , 1987, Analytical biochemistry.

[47]  K. Ishak Primary hepatic tumors in childhood. , 1976, Progress in liver diseases.

[48]  J. D. Watson Origin of Concatemeric T7DNA , 1972 .

[49]  J. Watson Origin of concatemeric T7 DNA. , 1972, Nature: New biology.