Sensitized Glaucoma Detection Using a Unique Template Based Correlation Filter and Undecimated Isotropic Wavelet Transform

Glaucoma is the most common cause of vision loss and its identification using image processing techniques is apparently becoming more important. This paper reports the development of an automated Glaucoma detection system based on image features of eye fundus photographs, which can be used to detect Glaucoma at an early stage. We have improved the sensitivity of Glaucoma detection by using Neuroretinal rim thickness, Neuroretinal rim area and vessel information of fundus image as additional features along with the cup-to-disc ratio feature that is normally used. A unique template based correlation technique using Pearson-r coefficients is employed to extract the features like cup-to-disc ratio, rim area and rim thickness. We have used vessel information as a new feature which is obtained by segmenting the vessels by employing an undecimated isotropic wavelet transform. Analysis of the extracted proposed features stored as a data base during each visit of the patient helps in monitoring the progression of the disease. An efficient methodology is developed showing promising results with better sensitivity and specificity in the classification of Glaucoma and healthy images, respectively.

[1]  Jayanthi Sivaswamy,et al.  Vessel Bend-Based Cup Segmentation in Retinal Images , 2010, 2010 20th International Conference on Pattern Recognition.

[2]  Dacheng Tao,et al.  Sparse Dissimilarity-Constrained Coding for Glaucoma Screening , 2015, IEEE Transactions on Biomedical Engineering.

[3]  Martin Kraus,et al.  Automatic no-reference quality assessment for retinal fundus images using vessel segmentation , 2013, Proceedings of the 26th IEEE International Symposium on Computer-Based Medical Systems.

[4]  K. Narasimhan,et al.  AN EFFICIENT AUTOMATED SYSTEM FOR GLAUCOMA DETECTION USING FUNDUS IMAGE , 2011 .

[5]  Jae S. Lim,et al.  Two-Dimensional Signal and Image Processing , 1989 .

[6]  F. Galton Regression Towards Mediocrity in Hereditary Stature. , 1886 .

[7]  Hiroshi Fujita,et al.  Determination of cup-to-disc ratio of optical nerve head for diagnosis of glaucoma on stereo retinal fundus image pairs , 2009, Medical Imaging.

[8]  Hiroshi Fujita,et al.  Automatic measurement of cup to disc ratio based on line profile analysis in retinal images , 2011, 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[9]  R. Hegadi,et al.  Computer Based Diagnosis of Glaucoma using Digital Fundus Images , 2013 .

[10]  U. Rajendra Acharya,et al.  Automated Diagnosis of Glaucoma Using Digital Fundus Images , 2009, Journal of Medical Systems.

[11]  J. Jonas,et al.  Parapapillary retinal vessel diameter in normal and glaucoma eyes. I. Morphometric data. , 1989, Investigative ophthalmology & visual science.

[12]  Andrew Hunter,et al.  Optic nerve head segmentation , 2004, IEEE Transactions on Medical Imaging.

[13]  P. Bankhead,et al.  Fast Retinal Vessel Detection and Measurement Using Wavelets and Edge Location Refinement , 2012, PloS one.

[14]  Nataraj A. Vijapur,et al.  Glaucoma detection by using Pearson-R correlation filter , 2015, 2015 International Conference on Communications and Signal Processing (ICCSP).