Safety and immunogenicity in animals of subunit influenza vaccine given intranasally with mutants of Escherichia coli heat-labile enterotoxin (LT)
暂无分享,去创建一个
R. Rappuoli | M. Pizza | B. Baudner | G. Giudice | A. Podda | S. Peppoloni | P. Ruggiero | M. Contorni | M. Morandi
[1] S. Mossad. Demystifying FluMist, a new intranasal, live influenza vaccine. , 2003, Cleveland Clinic journal of medicine.
[2] R. Walker,et al. Safety and immunogenicity of a live-attenuated influenza vaccine blended and filled at two manufacturing facilities. , 2003, Vaccine.
[3] M. Giuliani,et al. Enhancement of Protective Efficacy following Intranasal Immunization with Vaccine Plus a Nontoxic LTK63 Mutant Delivered with Nanoparticles , 2002, Infection and Immunity.
[4] J. Mcghee,et al. A dilemma for mucosal vaccination: efficacy versus toxicity using enterotoxin-based adjuvants. , 2002, Vaccine.
[5] M. Singh,et al. A novel bioadhesive intranasal delivery system for inactivated influenza vaccines. , 2001, Journal of controlled release : official journal of the Controlled Release Society.
[6] J. Donnelly,et al. Potency of a genetically detoxified mucosal adjuvant derived from the heat-labile enterotoxin of Escherichia coli (LTK63) is not adversely affected by the presence of preexisting immunity to the adjuvant. , 2001, The Journal of infectious diseases.
[7] G. Dougan,et al. Structure and mucosal adjuvanticity of cholera and Escherichia coli heat-labile enterotoxins. , 1999, Immunology today.
[8] G. Ott,et al. Intranasal Immunization of Mice with Influenza Vaccine in Combination with the Adjuvant LT-R72 Induces Potent Mucosal and Serum Immunity Which Is Stronger than That with Traditional Intramuscular Immunization , 1999, Infection and Immunity.
[9] G. Dougan,et al. Mucosal Adjuvanticity and Immunogenicity of LTR72, a Novel Mutant of Escherichia coli Heat-labile Enterotoxin with Partial Knockout of ADP-ribosyltransferase Activity , 1998, The Journal of experimental medicine.
[10] R. Rappuoli,et al. The adjuvant effect of a non‐toxic mutant of heat‐labile enterotoxin of Escherichia coli for the induction of measles virus‐specific CTL responses after intranasal co‐immunization with a synthetic peptide , 1996, Immunology.
[11] J. Kraehenbuhl,et al. Epithelial M Cells: Gateways for Mucosal Infection and Immunization , 1996, Cell.
[12] J. Kraehenbuhl,et al. Antigen sampling across epithelial barriers and induction of mucosal immune responses. , 1996, Annual review of immunology.
[13] M. Levine,et al. New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development. , 1983, Microbiological reviews.