Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway

[1]  J. Sambrook,et al.  Molecular Cloning: A Laboratory Manual , 2001 .

[2]  B. Dérijard,et al.  Cdc42 and PAK-mediated Signaling Leads to Jun Kinase and p38 Mitogen-activated Protein Kinase Activation (*) , 1995, The Journal of Biological Chemistry.

[3]  L. Zon,et al.  Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase , 1995, Nature.

[4]  C. Hall,et al.  Molecular Cloning of a New Member of the p21-Cdc42/Rac-activated Kinase (PAK) Family (*) , 1995, The Journal of Biological Chemistry.

[5]  Jiahuai Han,et al.  Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1 (*) , 1995, The Journal of Biological Chemistry.

[6]  L. Lim,et al.  Pheromone signalling in Saccharomyces cerevisiae requires the small GTP-binding protein Cdc42p and its activator CDC24 , 1995, Molecular and cellular biology.

[7]  J. Chernoff,et al.  Identification of a Mouse p21Cdc42/Rac Activated Kinase (*) , 1995, The Journal of Biological Chemistry.

[8]  A. Ashworth,et al.  An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1 , 1995, Science.

[9]  S. Reed,et al.  Role for the Rho-family GTPase Cdc42 in yeast mating-pheromone signal pathway , 1995, Nature.

[10]  K Nasmyth,et al.  growth and for cytokinesis in budding yeast. Ste20-like protein kinases are required for normal localization of cell , 2007 .

[11]  M. Karin,et al.  Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs , 1995, Cell.

[12]  P. Crespo,et al.  The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway , 1995, Cell.

[13]  J. Chant,et al.  Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[14]  F. McCormick,et al.  A novel serine kinase activated by rac1/CDC42Hs‐dependent autophosphorylation is related to PAK65 and STE20. , 1995, The EMBO journal.

[15]  C. Nobes,et al.  Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia , 1995, Cell.

[16]  L. Lim,et al.  The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts , 1995, Molecular and cellular biology.

[17]  A. Hall,et al.  A novel type of myosin implicated in signalling by rho family GTPases. , 1995, EMBO Journal.

[18]  I. Herskowitz.  MAP kinase pathways in yeast: For mating and more , 1995, Cell.

[19]  A. Hall,et al.  GAPs for rho-related GTPases. , 1994, Trends in genetics : TIG.

[20]  L. Chong,et al.  The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells , 1994, Cell.

[21]  G. Sprague,,et al.  Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade. , 1994, Genetics.

[22]  E. Elion,et al.  Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae , 1994, Cell.

[23]  S. Bagrodia,et al.  Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85. , 1994, The Journal of biological chemistry.

[24]  J. Kehrl,et al.  Differential expression of a novel protein kinase in human B lymphocytes. Preferential localization in the germinal center. , 1994, The Journal of biological chemistry.

[25]  Sally J. Leevers,et al.  Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane , 1994, Nature.

[26]  J. Woodgett,et al.  The stress-activated protein kinase subfamily of c-Jun kinases , 1994, Nature.

[27]  M. Karin,et al.  JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain , 1994, Cell.

[28]  L. Lim,et al.  A brain serine/threonine protein kinase activated by Cdc42 and Rac1 , 1994, Nature.

[29]  R. Weinberg,et al.  The pathway to signal achievement , 1993, Nature.

[30]  L. Lim,et al.  A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42 , 1993, Nature.

[31]  M. Whiteway,et al.  The protein kinase homologue Ste20p is required to link the yeast pheromone response G‐protein beta gamma subunits to downstream signalling components. , 1992, The EMBO journal.

[32]  Anne J. Ridley,et al.  The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors , 1992, Cell.

[33]  Anne J. Ridley,et al.  The small GTP-binding protein rac regulates growth factor-induced membrane ruffling , 1992, Cell.

[34]  U. Rapp,et al.  Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase. , 1992, Genes & development.

[35]  I. Herskowitz,et al.  A yeast gene (BEM1) necessary for cell polarization whose product contains two SH3 domains , 1992, Nature.

[36]  A. Hall,et al.  Microinjection of recombinant p21rho induces rapid changes in cell morphology , 1990, The Journal of cell biology.

[37]  J. Pringle,et al.  CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae , 1990, The Journal of cell biology.

[38]  W. Rutter,et al.  A murine fer testis-specific transcript (ferT) encodes a truncated Fer protein , 1990, Molecular and cellular biology.

[39]  R. Sikorski,et al.  A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. , 1989, Genetics.

[40]  G. Fink,et al.  Two genes required for cell fusion during yeast conjugation: evidence for a pheromone-induced surface protein , 1987, Molecular and cellular biology.

[41]  R. Sikorski,et al.  In vitro mutagenesis and plasmid shuffling: from cloned gene to mutant yeast. , 1991, Methods in enzymology.

[42]  F. Sherman.  Getting started with yeast. , 1991, Methods in enzymology.

[43]  Thomas A. Kunkel,et al.  Rapid and efficient site-specific mutagenesis without phenotypic selection. , 1985, Proceedings of the National Academy of Sciences of the United States of America.