Genetics of hair graying with age

[1]  Congfen He,et al.  Exploration of potential lipid biomarkers for age‐induced hair graying by lipidomic analyses of hair shaft roots with follicular tissue attached , 2022, Journal of cosmetic dermatology.

[2]  F. Papaccio,et al.  Focus on the Contribution of Oxidative Stress in Skin Aging , 2022, Antioxidants.

[3]  Shulian Wu,et al.  Modeling human gray hair by irradiation as a valuable tool to study aspects of tissue aging , 2022, GeroScience.

[4]  Sijie Wu,et al.  Single-cell transcriptomics reveals lineage trajectory of human scalp hair follicle and informs mechanisms of hair graying , 2022, Cell discovery.

[5]  J. Li,et al.  Exaggerated false positives by popular differential expression methods when analyzing human population samples , 2022, Genome Biology.

[6]  Jing Chen,et al.  Hair Graying Regulators Beyond Hair Follicle , 2022, Frontiers in Physiology.

[7]  A. Martins,et al.  Nanomaterials in hair care and treatment. , 2022, Acta biomaterialia.

[8]  M. Philpott Watching hair turn grey , 2021, eLife.

[9]  Yanzhuo Zhang,et al.  PIN1 Protects Hair Cells and Auditory HEI-OC1 Cells against Senescence by Inhibiting the PI3K/Akt/mTOR Pathway , 2021, Oxidative medicine and cellular longevity.

[10]  M. Tognon,et al.  microRNAs in the Regulation of Melanogenesis , 2021, International journal of molecular sciences.

[11]  Lily Lei,et al.  Epigenetic regulation of melanogenesis , 2021, Ageing Research Reviews.

[12]  J. H. Lee,et al.  Cellular Senescence and Inflammaging in the Skin Microenvironment , 2021, International journal of molecular sciences.

[13]  R. Paus,et al.  Dermal adipose tissue secretes HGF to promote human hair growth and pigmentation. , 2021, The Journal of investigative dermatology.

[14]  Masahide Takahashi,et al.  Hair graying with aging in mice carrying oncogenic RET , 2020, Aging cell.

[15]  D. Tobin,et al.  Stress-sensing in the human greying hair follicle: Ataxia Telangiectasia Mutated (ATM) depletion in hair bulb melanocytes in canities-prone scalp , 2020, Scientific Reports.

[16]  Y. Ramot,et al.  Translational Neuroendocrinology of Human Skin: Concepts and Perspectives. , 2020, Trends in molecular medicine.

[17]  D. Tobin,et al.  The biology of human hair greying , 2020, Biological reviews of the Cambridge Philosophical Society.

[18]  R. Płoski,et al.  Exploring the possibility of predicting human head hair greying from DNA using whole-exome and targeted NGS data , 2020, BMC Genomics.

[19]  A. Regev,et al.  775 Hyperactivation of sympathetic nerves drives melanocyte stem cell depletion , 2020 .

[20]  N. Gianneschi,et al.  Mimicking Natural Human Hair Pigmentation with Synthetic Melanin , 2020, ACS central science.

[21]  Kun Zhang,et al.  Tools for the analysis of high-dimensional single-cell RNA sequencing data , 2020, Nature Reviews Nephrology.

[22]  Joseph Bergenstråhle,et al.  Super-resolved spatial transcriptomics by deep data fusion , 2020, Nature Biotechnology.

[23]  O. Elemento,et al.  The aging skin microenvironment dictates stem cell behavior , 2020, Proceedings of the National Academy of Sciences.

[24]  R. Paus,et al.  Fluoxetine promotes human hair follicle pigmentation ex vivo: serotonin reuptake inhibition as a new antigreying strategy? , 2019, The British journal of dermatology.

[25]  W. Pavan,et al.  The Genetics of Human Skin and Hair Pigmentation. , 2019, Annual review of genomics and human genetics.

[26]  Laurent Gil,et al.  Ensembl variation resources , 2018, Database J. Biol. Databases Curation.

[27]  S. Rosset,et al.  Estimating SNP-Based Heritability and Genetic Correlation in Case-Control Studies Directly and with Summary Statistics. , 2018, American journal of human genetics.

[28]  W. Pavan,et al.  A direct link between MITF, innate immunity, and hair graying , 2018, PLoS biology.

[29]  Guy A Rouleau,et al.  Genetics of Intracranial Aneurysms. , 2018, Stroke.

[30]  David J. Wu,et al.  Secure genome-wide association analysis using multiparty computation , 2018, Nature Biotechnology.

[31]  S. Chang,et al.  Novel regulation of melanogenesis by adiponectin via the AMPK/CRTC pathway , 2017, Pigment cell & melanoma research.

[32]  S. Morrison,et al.  Identification of hair shaft progenitors that create a niche for hair pigmentation , 2017, Genes & development.

[33]  M. Šitum,et al.  Novel technique for repigmentation of senescence grey hair , 2017, Dermatologic therapy.

[34]  Minoru Kanehisa,et al.  KEGG: new perspectives on genomes, pathways, diseases and drugs , 2016, Nucleic Acids Res..

[35]  M. Askarian-Amiri,et al.  Signaling Pathways in Melanogenesis , 2016, International journal of molecular sciences.

[36]  D. Balding,et al.  A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features , 2016, Nature Communications.

[37]  J. Hoeijmakers,et al.  Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis , 2016, Science.

[38]  Anne Tybjærg-Hansen,et al.  Visible aging signs as risk markers for ischemic heart disease: Epidemiology, pathogenesis and clinical implications , 2016, Ageing Research Reviews.

[39]  Sanjeev Gupta,et al.  A minimally invasive, scarless technique of donor tissue harvesting for noncultured epidermal cell suspension transplantation in vitiligo. , 2015, Journal of the American Academy of Dermatology.

[40]  A. Gomes,et al.  Hair Coloration by Gene Regulation: Fact or Fiction? , 2015, Trends in biotechnology.

[41]  Minoru Kanehisa,et al.  KEGG as a reference resource for gene and protein annotation , 2015, Nucleic Acids Res..

[42]  Thanigaimalai Pillaiyar,et al.  Inhibitors of melanogenesis: a patent review (2009 – 2014) , 2015, Expert opinion on therapeutic patents.

[43]  Lei Wang,et al.  Organ-Level Quorum Sensing Directs Regeneration in Hair Stem Cell Populations , 2015, Cell.

[44]  Hyoseung Shin,et al.  Association of premature hair graying with family history, smoking, and obesity: a cross-sectional study. , 2015, Journal of the American Academy of Dermatology.

[45]  Juancarlos Chan,et al.  Gene Ontology Consortium: going forward , 2014, Nucleic Acids Res..

[46]  B. Andersen,et al.  Neuroendocrinology of the hair follicle: principles and clinical perspectives. , 2014, Trends in molecular medicine.

[47]  T. Kunisada,et al.  Prevention of hair graying by factors that promote the growth and differentiation of melanocytes , 2014, The Journal of dermatology.

[48]  H. Jakubowski,et al.  Methionine-induced hyperhomocysteinemia and bleomycin hydrolase deficiency alter the expression of mouse kidney proteins involved in renal disease. , 2014, Molecular genetics and metabolism.

[49]  J. Hoeijmakers,et al.  Understanding nucleotide excision repair and its roles in cancer and ageing , 2014, Nature Reviews Molecular Cell Biology.

[50]  O. Lee,et al.  Regenerative hair waves in aging mice and extra-follicular modulators Follistatin, Dkk1 and Sfrp4 , 2014, The Journal of investigative dermatology.

[51]  S. Leachman,et al.  Melanocytes as Instigators and Victims of Oxidative Stress , 2014, The Journal of investigative dermatology.

[52]  Theresa Guo,et al.  A Polymorphism in IRF4 Affects Human Pigmentation through a Tyrosinase-Dependent MITF/TFAP2A Pathway , 2013, Cell.

[53]  R. Wilson,et al.  The Next-Generation Sequencing Revolution and Its Impact on Genomics , 2013, Cell.

[54]  W. Pavan,et al.  A Dual Role for SOX10 in the Maintenance of the Postnatal Melanocyte Lineage and the Differentiation of Melanocyte Stem Cell Progenitors , 2013, PLoS genetics.

[55]  M. Kayser,et al.  Colorful DNA polymorphisms in humans. , 2013, Seminars in cell & developmental biology.

[56]  J. Ioannidis,et al.  Meta-analysis methods for genome-wide association studies and beyond , 2013, Nature Reviews Genetics.

[57]  B. Klapp,et al.  Profiling mRNA of the graying human hair follicle constitutes a promising state-of-the-art tool to assess its aging: an exemplary report. , 2013, The Journal of investigative dermatology.

[58]  G. Loussouarn,et al.  Greying of the human hair: a worldwide survey, revisiting the ‘50’ rule of thumb , 2012, The British journal of dermatology.

[59]  J. Shapiro,et al.  Deficiency in Nucleotide Excision Repair Family Gene Activity, Especially ERCC3, Is Associated with Non-Pigmented Hair Fiber Growth , 2012, PloS one.

[60]  Jolon M. Dyer,et al.  An Updated Nomenclature for Keratin-Associated Proteins (KAPs) , 2012, International journal of biological sciences.

[61]  Y. Lee,et al.  Hair greying is associated with active hair growth , 2011, The British journal of dermatology.

[62]  D. Petersohn,et al.  Ageing processes influence keratin and KAP expression in human hair follicles , 2011, Experimental dermatology.

[63]  A. Mes-Masson,et al.  KIF1A, an axonal transporter of synaptic vesicles, is mutated in hereditary sensory and autonomic neuropathy type 2. , 2011, American journal of human genetics.

[64]  Christopher G Chute,et al.  For Personal Use. Mass Reproduce Only with Permission from Mayo Clinic Proceedings a . Original Article Mayo Genome Consortia: a Genotype-phenotype Resource for Genome-wide Association Studies with an Application to the Analysis of Circulating Bilirubin Levels , 2022 .

[65]  D. Tobin,et al.  Human hair follicle and epidermal melanocytes exhibit striking differences in their aging profile which involves catalase. , 2011, The Journal of investigative dermatology.

[66]  T. Polefka,et al.  Grey hair: clinical investigation into changes in hair fibres with loss of pigmentation in a photoprotected population , 2011, International journal of cosmetic science.

[67]  Dong Woon Kim,et al.  Downregulation of NFAT2 promotes melanogenesis in B16 melanoma cells , 2010, Anatomy & cell biology.

[68]  A. Christiano,et al.  Biology and genetics of hair. , 2010, Annual review of genomics and human genetics.

[69]  J. Roes,et al.  Key roles for transforming growth factor beta in melanocyte stem cell maintenance. , 2010, Cell stem cell.

[70]  L. Larue,et al.  Transgenic expression of Notch in melanocytes demonstrates RBP‐Jκ‐dependent signaling , 2010, Pigment cell & melanoma research.

[71]  Michael Catt,et al.  Why Some Women Look Young for Their Age , 2009, PloS one.

[72]  S. Artandi,et al.  Stem cell aging and aberrant differentiation within the niche. , 2009, Cell stem cell.

[73]  H Decker,et al.  Senile hair graying: H2O2‐mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[74]  N. Binh,et al.  Genotoxic Stress Abrogates Renewal of Melanocyte Stem Cells by Triggering Their Differentiation , 2009, Cell.

[75]  R. Sturm,et al.  Molecular genetics of human pigmentation diversity. , 2009, Human molecular genetics.

[76]  R. Paus,et al.  Thyroid hormones directly alter human hair follicle functions: anagen prolongation and stimulation of both hair matrix keratinocyte proliferation and hair pigmentation. , 2008, The Journal of clinical endocrinology and metabolism.

[77]  Snæbjörn Pálsson,et al.  Two newly identified genetic determinants of pigmentation in Europeans , 2008, Nature Genetics.

[78]  S. Bayliss,et al.  The genetics of hair shaft disorders. , 2008, Journal of the American Academy of Dermatology.

[79]  T. Yoon,et al.  Changing expression of the genes related to human hair graying. , 2008, European journal of dermatology : EJD.

[80]  F. Hu,et al.  A Genome-Wide Association Study Identifies Novel Alleles Associated with Hair Color and Skin Pigmentation , 2008, PLoS genetics.

[81]  Zhaohui S. Qin,et al.  A second generation human haplotype map of over 3.1 million SNPs , 2007, Nature.

[82]  A. Bhandoola,et al.  Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss. , 2007, Cell stem cell.

[83]  D. Fisher,et al.  Melanocyte biology and skin pigmentation , 2007, Nature.

[84]  B. Klapp,et al.  Towards a “free radical theory of graying”: melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[85]  Björn Sjögreen,et al.  The real-time polymerase chain reaction. , 2006, Molecular aspects of medicine.

[86]  R. Paus,et al.  Human hair follicles display a functional equivalent of the hypothalamic‐pituitary‐adrenal (HPA) axis and synthesize cortisol , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[87]  D. Fisher,et al.  Mechanisms of Hair Graying: Incomplete Melanocyte Stem Cell Maintenance in the Niche , 2005, Science.

[88]  N. Copeland,et al.  Melanocytes and the microphthalmia transcription factor network. , 2004, Annual review of genetics.

[89]  J. Jachowicz,et al.  Optical properties of hair--detailed examination of specular reflection patterns in various hair types. , 2004, Journal of cosmetic science.

[90]  D. Tobin,et al.  Hair cycle and hair pigmentation: dynamic interactions and changes associated with aging. , 2004, Micron.

[91]  B. Bernard,et al.  Human hair greying is linked to a specific depletion of hair follicle melanocytes affecting both the bulb and the outer root sheath , 2004, The British journal of dermatology.

[92]  S. Blumen,et al.  A locus for complicated hereditary spastic paraplegia maps to chromosome 1q24‐q32 , 2003, Annals of neurology.

[93]  J. Rees Genetics of hair and skin color. , 2003, Annual review of genetics.

[94]  F. Leroy,et al.  Current research on ethnic hair. , 2003, Journal of the American Academy of Dermatology.

[95]  Mayumi Ito,et al.  Label-retaining cells in the bulge region are directed to cell death after plucking, followed by healing from the surviving hair germ. , 2002, The Journal of investigative dermatology.

[96]  Kenji Kohno,et al.  Identification of a Novel Non-structural Maintenance of Chromosomes (SMC) Component of the SMC5-SMC6 Complex Involved in DNA Repair* , 2002, The Journal of Biological Chemistry.

[97]  D. Tobin,et al.  Graying: gerontobiology of the hair follicle pigmentary unit , 2001, Experimental Gerontology.

[98]  B. Bernard,et al.  Melanocyte subpopulation turnover during the human hair cycle: an immunohistochemical study. , 2000, Pigment cell research.

[99]  D. Tobin,et al.  Do hair bulb melanocytes undergo apoptosis during hair follicle regression (catagen)? , 1998, The Journal of investigative dermatology.

[100]  P. Schnohr,et al.  Longevity and gray hair, baldness, facial wrinkles, and arcus senilis in 13,000 men and women: the Copenhagen City Heart Study. , 1998, The journals of gerontology. Series A, Biological sciences and medical sciences.

[101]  W. Nagl Different growth rates of pigmented and white hair in the beard: differentiation vs. proliferation? , 1995, The British journal of dermatology.

[102]  S. Korsmeyer,et al.  Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair , 1993, Cell.

[103]  E. Keogh,et al.  Rate of Greying of Human Hair , 1965, Nature.

[104]  R. Paus,et al.  Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: an update. , 2013, Journal of dermatological science.

[105]  T. Honda,et al.  Human Hair Follicle and Epidermal Melanocytes Exhibit Striking Differences in Their Aging Profile which Involves Catalase , 2011 .

[106]  L. Mullenders,et al.  Transcription-coupled nucleotide excision repair in mammalian cells: molecular mechanisms and biological effects , 2008, Cell Research.

[107]  R. Paus,et al.  The human hair bulb is a source and target of CRH. , 2004, The Journal of investigative dermatology.

[108]  D. Van Neste Thickness, medullation and growth rate of female scalp hair are subject to significant variation according to pigmentation and scalp location during ageing. , 2004, European journal of dermatology : EJD.