Atypical clinical presentation of an Arthroderma gypseum infection in a renal transplant recipient

ABSTRACT Dermatophytes are known as a common cause of superficial mycosis, but atypical presentations in immunosuppressed patients make the diagnosis more challenging. Here, we report a case of a 39-year-old patient, a renal transplant recipient from a living donor, who presented with atypical cutaneous lesions of lower extremities caused by Arthroderma gypseum (Nannizzia gypsea), four months after receiving a renal transplant. It is important to highlight the importance of the early detection of fungal infections in immunosuppressed patients. Clinicians should have a high degree of suspicion for the early detection and treatment of the cases.

[1]  C. Festa Neto,et al.  Skin lesions in organ transplant recipients: a study of 177 consecutive Brazilian patients , 2018, International journal of dermatology.

[2]  B. Rutkowski,et al.  Superficial fungal infections in renal transplant recipients. , 2014, Transplantation proceedings.

[3]  D. Hospenthal,et al.  Disseminated dermatophytosis in a patient with hereditary hemochromatosis and hepatic cirrhosis: case report and review of the literature. , 2010, Medical mycology.

[4]  R. Saha,et al.  Disseminated nodular granulomatous perifolliculitis. , 2007, Indian journal of medical microbiology.

[5]  R. Hay,et al.  Deep dermatophytosis: rare infections or common, but unrecognised, complications of lymphatic spread? , 2004, Current opinion in infectious diseases.

[6]  R. A. Araviysky,et al.  Deep generalized trichophytosis , 1975, Mycopathologia.

[7]  D. Silvers,et al.  Invasive Trichophyton rubrum infection in the immunocompromised host: report of three cases. , 1995, Journal of the American Academy of Dermatology.

[8]  B. Elewski,et al.  Dermatophytes as opportunistic pathogens. , 1994, Journal of the American Academy of Dermatology.

[9]  G. Lestringant,et al.  Deep Dermatophytosis to Trichophyton rubrum and T. verrucosum in an Immunosuppressed Patient , 1988, International journal of dermatology.

[10]  J. Salaman,et al.  Cutaneous fungal infection following renal transplantation: a case control study , 1987, The British journal of dermatology.

[11]  R. Hay,et al.  Deep (subcutaneous) dermatophyte infection presenting with unilateral lymphoedema , 1987, Clinical and experimental dermatology.

[12]  E. Bottone,et al.  Invasive trichophyton rubrum infection in an immunocompromised host. Case report and review of the literature. , 1987, The American journal of medicine.

[13]  R. Hay,et al.  Cell-mediated immunity in experimental murine dermatophytosis. II. Adoptive transfer of immunity to dermatophyte infection by lymphoid cells from donors with acute or chronic infections. , 1984, Immunology.

[14]  C. Ponticelli,et al.  Cutaneous manifestations in renal transplant recipients. , 1983, Nephron.

[15]  R. Snyderman,et al.  Generalized microsporum audoninii infection and depressed cellular immunity associated with a missing plasma factor required for lymphocyte blastogenesis. , 1977, The American journal of medicine.

[16]  M. PereiroMiguens.  Granulomatous mycosis caused by M. gypseum , 1976 .

[17]  H. Luscombe,et al.  NODULAR GRANULOMATOUS PERIFOLLICULITIS CAUSED BY MICROSPORUM GYPSEUM. , 1964, Archives of dermatology.

[18]  J. W. Wilson,et al.  Nodular granulomatous perifolliculitis of the legs caused by Trichophyton rubrum. , 1954, A.M.A. archives of dermatology and syphilology.